The Unique Challenges Facing HIV-Positive Patients Who Smoke Cigarettes: HIV Viremia, Art Adherence, Engagement in HIV care, and Concurrent Substance Use
Open accessAbstract
Evidence suggests that smoking may have negative associations with HIV health outcomes. The smoking rate in our sample of people living with HIV (N = 333) was triple that of the general population (57 v. 19 %). Regression analyses revealed that (smokers v. non-smokers) reported lower medication adherence (unstandardized beta = 9.01) and were more likely to have a detectable viral load (OR = 2.85, 95 % CI [1.53-5.30]). Smokers attended fewer routine medical visits (β = -0.16) and were more likely to report recent hospitalization (OR = 1.89, 95 % CI [0.99, 3.57]). Smokers ranked "health" as less important to their quality of life (β = -0.13) and were more likely to report problematic alcohol (OR = 2.40, 95 % CI [1.35, 4.30]), cocaine (OR = 2.87, 95 % CI [1.48-5.58]), heroin (OR = 4.75, 95 % CI [1.01, 22.30]), or marijuana use (OR = 3.08, 95 % CI [1.76-5.38]). Findings underscore the need for integrated behavioral smoking cessation interventions and routine tobacco screenings in HIV primary care.
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Rates of cigarette smoking among PLWHA are up to at least three times that of the general population.
“rates of cigarette smoking among PLWHA up to at least three times that of the general population (Niaura et al., 2000; O’Cleirigh et al., 2014).”
From A qualitative study of the feasibility and acceptability of a smoking cessation program for people living with HIV and emotional dysregulation. (2019) · cites this paper as O’Cleirigh et al., 2014
People living with HIV/AIDS (PLWHA) are at an especially increased risk for developing medical complications as a result of cigarette smoking.
“People living with HIV/AIDS (PLWHA) are at an especially increased risk for developing medical complications as a result of cigarette smoking”
From A qualitative study of the feasibility and acceptability of a smoking cessation program for people living with HIV and emotional dysregulation. (2019) · cites this paper as O’Cleirigh et al., 2014
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O'Cleirigh, C., Zvolensky, M. J., Smits, J. A. J., Labbe, A. K., Coleman, J. N., Wilner, J. G., Stanton, A. M., Gonzalez, A., Garey, L., Regenauer, K. S., et al. (2018) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000001787 · Cited by 41 · see citing works
Self-citationLabbe, A. K., Wilner, J. G., Kosiba, J. D., Gonzalez, A., Smits, J. A., Zvolensky, M. J., Norton, P. J., & O’Cleirigh, C. (2017) · Cognitive and Behavioral Practice · doi:10.1016/j.cbpra.2016.03.009 · Cited by 8 · see citing works
Self-citationGarey, L., Wirtz, M. R., Labbe, A. K., Zvolensky, M. J., Smits, J. A. J., Giordano, T. P., Rosenfield, D., Robbins, G. K., Levy, D. E., McKetchnie, S. M., et al. (2021) · Contemporary Clinical Trials · doi:10.1016/j.cct.2021.106420 · Cited by 3 · see citing works
Self-citationLabbe, A. K., Wilner, J. G., Coleman, J. N., Marquez, S. M., Kosiba, J. D., Zvolensky, M. J., Smits, J. A. J., Norton, P. J., Rosenfield, D., & O'Cleirigh, C. (2019) · AIDS Care · doi:10.1080/09540121.2018.1533225 · Cited by 3 · see citing works
“People living with HIV/ AIDS (PLWHA) are at an especially increased risk for developing medical complications as a result of cigarette smoking with rates of cigarette smoking among PLWHA up to at least three times that of the general population (Niaura et al., 2000; O’Cleirigh et al., 2014).”
BackgroundSelf-citation
- Authors
- O’Cleirigh, C., Valentine, S. E., Pinkston, M., Herman, D., Bedoya, C. A., Gordon, J. R., & Safren, S. A.
- Affiliations
- Harvard University (US)
- Miriam Hospital (US)
- Butler Hospital (US)
- Corresponding author
- O’Cleirigh, Conall
- ORCID
- Venue
- AIDS and Behavior
- Published
- 2014-04-27
- Volume
- 19
- Issue
- 1
- Pages
- 178-185
- ISSN
- 1090-7165 (ISSN-L)
- 1573-3254
- PMC
- PMC4415512
- OpenAlex
- W2111389116
- Cited by
- 87
- References
- 4
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 6 · 2023: 5 · 2022: 9 · 2021: 9 · 2020: 7 · 2019: 11 · 2018: 12 · 2017: 3 · 2016: 10 · 2015: 6 · 2014: 3
- FWCI
- 4.57
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- AIDS and Behavior (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (R01MH084757, K24MH094214)
- Topics
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
- Keywords
- HIV, smoking, tobacco use, HIV viremia, antiretroviral therapy adherence, HIV care engagement, concurrent substance use, alcohol consumption, cocaine use, heroin use, cannabis use, quality of life, smoking cessation interventions, tobacco use screening, HIV primary care
- MeSH terms
- Cross-Sectional Studies, Depression, Female, Humans, Male, Middle Aged, Referral and Consultation, Risk Factors, Smoking, United States, Viremia, Health Behavior, HIV Infections, Prevalence, Smoking Cessation, Drug Monitoring, Viral Load, Substance-Related Disorders, Medication Adherence
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