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Cited by 126Smoking Behavior and CessationSubstance Abuse Treatment and OutcomesBehavioral Health and Interventions

Motivation and patch treatment for HIV+ smokers: a randomized controlled trial

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Lloyd‐Richardson, Elizabeth E., Stanton, Cassandra A., Papandonatos, George D., Shadel, William G., Stein, Michael, Tashima, Karen, Flanigan, Timothy, Morrow, Kathleen +2 more·2009·Addiction
DOI 10.1111/j.1360-0443.2009.02623.xPMC PMC2763031
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Abstract

Aims To test the efficacy of two smoking cessation interventions in a HIV positive (HIV+) sample: standard care (SC) treatment plus nicotine replacement therapy (NRT) versus more intensive motivationally enhanced (ME) treatment plus NRT. Design Randomized controlled trial. Setting HIV+ smoker referrals from eight immunology clinics in the northeastern United States. Participants A total of 444 participants enrolled in the study (mean age = 42.07 years; 63.28% male; 51.80% European American; mean cigarettes/day = 18.27). Interventions SC participants received two brief sessions with a health educator. Those setting a quit date received self‐help quitting materials and NRT. ME participants received four sessions of motivational counseling and a quit‐day counseling call. All ME intervention materials were tailored to the needs of HIV+ individuals. Measurements Biochemically verified 7‐day abstinence rates at 2‐month, 4‐month and 6‐month follow‐ups. Findings Intent‐to‐treat (ITT) abstinence rates at 2‐month, 4‐month and 6‐month follow‐ups were 12%, 9% and 9%, respectively, in the ME condition, and 13%, 10% and 10%, respectively, in the SC condition, indicating no between‐group differences. Among 412 participants with treatment utilization data, 6‐month ITT abstinence rates were associated positively with low nicotine dependence (P = 0.02), high motivation to quit (P = 0.04) and Hispanic American race/ethnicity (P = 0.02). Adjusting for these variables, each additional NRT contact improved the odds of smoking abstinence by a third (odds ratio = 1.32, 95% confidence interval = 0.99–1.75). Conclusions Motivationally enhanced treatment plus NRT did not improve cessation rates over and above standard care treatment plus NRT in this HIV+ sample of smokers. Providers offering brief support and encouraging use of nicotine replacement may be able to help HIV+ patients to quit smoking.

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Research works printed but not linked: 4

  1. [1]CDC HIV/AIDS Surveillance Report, Revised Edition 2007
  2. [35]Kohout FJ Berkman LF Evans DA Cornoni-Huntley J Two shorter forms of the CES-D (Center for Epidemiological Studies Depression) depression symptoms index J Aging Health 1993 5 179 193 10125443
  3. [36]Radloff LS The CES-D Scale: A self-report depressive scale for research in the general population Journal of Applied Psychological Measurement 1977 1 385 401
  4. [39]Shepard DS Neighbors CJ Lloyd-Richardson EE Beaston-Blaakman A Farrell N Niaura R Assessing costs and time of counseling services for HIV+ patients. XIV International AIDS Conference 2002 Barcelona, Spain Monduzzi Editore, International Proceedings Division (paper C708s9823)

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Authors
Lloyd‐Richardson, E. E., Stanton, C. A., Papandonatos, G. D., Shadel, W. G., Stein, M., Tashima, K., Flanigan, T., Morrow, K., Neighbors, C., & Niaura, R.
Affiliations
  • University of Massachusetts Dartmouth (US)
  • Brown University (US)
  • RAND Corporation (US)
  • National Center on Addiction and Substance Abuse at Columbia University (US)
Corresponding author
Lloyd‐Richardson, Elizabeth E.
ORCID
Venue
Addiction
Publisher
Wiley
Published
2009-10-09
Volume
104
Issue
11
Pages
1891-1900
ISSN
  • 0965-2140 (ISSN-L)
  • 1360-0443
DOI
10.1111/j.1360-0443.2009.02623.x
PMC
PMC2763031
OpenAlex
W2066729021
Semantic Scholar
9872242e227c6abd7ae920d09bf862bf6bcec1b6
Cited by
125
References
36
Citations by year
2026: 3 · 2025: 1 · 2024: 7 · 2023: 2 · 2022: 3 · 2021: 10 · 2020: 2 · 2019: 8 · 2018: 4 · 2017: 4 · 2016: 17 · 2015: 14 · 2014: 10 · 2013: 13 · 2012: 12
FWCI
5.68
Type
journal article
Language
en
Open access
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Addiction (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Heart, Lung, and Blood Institute (K23HL069987)
  • National Institute on Drug Abuse (R01-DA12344-06, R01DA012344)
  • National Cancer Institute (K07CA095623, P50CA084719)
  • National Institute of Allergy and Infectious Diseases (P30AI042853)
Topics
  • Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Social Sciences › Psychology › Applied Psychology › Behavioral Health and Interventions
Keywords
smoking cessation, nicotine replacement therapy, motivation enhancement, motivational counseling, nicotine dependence, abstinence rates, brief intervention, Hispanic Americans, race and ethnicity
MeSH terms
Administration, Cutaneous, Adult, Black or African American, Counseling, Female, Hispanic or Latino, HIV Seropositivity, Humans, Male, Motivation, New England, Nicotine, Smoking, Program Evaluation, Smoking Cessation, Treatment Outcome, White People

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