The DOI matches its Crossref record; 81 of the 81 references it cites were found in a registry or an index.
Sex hormones and skeletal muscle weakness
Open accessAbstract
Human ageing is accompanied with deterioration in endocrine functions the most notable and well characterized of which being the decrease in the production of sex hormones. Current research literature suggests that low sex hormone concentration may be among the key mechanism for sarcopenia and muscle weakness. Within the European large scale MYOAGE project, the role of sex hormones, estrogens and testosterone, in causing the aging-related loss of muscle mass and function was further investigated. Hormone replacement therapy (HRT) in women is shown to diminish age-associated muscle loss, loss in fast muscle function (power), and accumulation of fat in skeletal muscle. Further HRT raises the protein synthesis rate in skeletal muscle after resistance training, and has an anabolic effect upon connective tissue in both skeletal muscle and tendon, which influences matrix structure and mechanical properties. HRT influences gene expression in e.g. cytoskeletal and cell-matrix proteins, has a stimulating effect upon IGF-I, and a role in IL-6 and adipokine regulation. Despite low circulating steroid-hormone level, postmenopausal women have a high local concentration of steroidogenic enzymes in skeletal muscle.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Hence, the muscle mass and strength weaken with the reduced testosterone and estrogen concentrations (50).”
From Diabetes and Sarcopenic Obesity: Pathogenesis, Diagnosis, and Treatments (2020) · cites this paper as [50]
Citations
Cites
Frailty in Older Adults: Evidence for a Phenotype
Fried, L. P., Tangen, C. M., Walston, J., Newman, A. B., Hirsch, C., Gottdiener, J., Seeman, T., Tracy, R., Kop, W. J., Burke, G., et al. (2001) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/56.3.m146 · Cited by 24,907
Inflamm‐aging: An Evolutionary Perspective on Immunosenescence
FRANCESCHI, C., BONAFÈ, M., VALENSIN, S., OLIVIERI, F., DE LUCA, M., OTTAVIANI, E., & DE BENEDICTIS, G. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06651.x · Cited by 5,358
Longitudinal Effects of Aging on Serum Total and Free Testosterone Levels in Healthy Men
Harman, S. M., Metter, E. J., Tobin, J. D., Pearson, J., & Blackman, M. R. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.2.7219 · Cited by 2,760
Feldman, H. A., Longcope, C., Derby, C. A., Johannes, C. B., Araujo, A. B., Coviello, A. D., Bremner, W. J., & McKinlay, J. B. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.2.8201 · Cited by 1,861
The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men
Bhasin, S., Storer, T. W., Berman, N., Callegari, C., Clevenger, B., Phillips, J., Bunnell, T. J., Tricker, R., Shirazi, A., & Casaburi, R. (1996) · New England Journal of Medicine · doi:10.1056/nejm199607043350101 · Cited by 1,659
Rommel, C., Bodine, S. C., Clarke, B. A., Rossman, R., Nunez, L., Stitt, T. N., Yancopoulos, G. D., & Glass, D. J. (2001) · Nature Cell Biology · doi:10.1038/ncb1101-1009 · Cited by 1,583
Adverse Events Associated with Testosterone Administration
Basaria, S., Coviello, A. D., Travison, T. G., Storer, T. W., Farwell, W. R., Jette, A. M., Eder, R., Tennstedt, S., Ulloor, J., Zhang, A., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1000485 · Cited by 1,494
Gray, A., Feldman, H. A., McKinlay, J. B., & Longcope, C. (1991) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-73-5-1016 · Cited by 1,104
Razandi, M., Pedram, A., Greene, G. L., & Levin, E. R. (1999) · Molecular Endocrinology · doi:10.1210/mend.13.2.0239 · Cited by 1,075
Changes in Proinflammatory Cytokine Activity after Menopause
Pfeilschifter, J., Köditz, R., Pfohl, M., & Schatz, H. (2002) · Endocrine Reviews · doi:10.1210/edrv.23.1.0456 · Cited by 929
Cited by
Sorted by citations
Sarcopenia: Aging-Related Loss of Muscle Mass and Function
Larsson, L., Degens, H., Li, M., Salviati, L., Lee, Y. I., Thompson, W., Kirkland, J. L., & Sandri, M. (2019) · Physiological Reviews · doi:10.1152/physrev.00061.2017 · Cited by 1,797
The Sick and the Weak: Neuropathies/Myopathies in the Critically Ill
Friedrich, O., Reid, M. B., den Berghe, G. V., Vanhorebeek, I., Hermans, G., Rich, M. M., & Larsson, L. (2015) · Physiological Reviews · doi:10.1152/physrev.00028.2014 · Cited by 409
Osteoporosis and Sarcopenia Increase Frailty Syndrome in the Elderly
Greco, E. A., Pietschmann, P., & Migliaccio, S. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00255 · Cited by 348
Pathophysiology and mechanisms of primary sarcopenia (Review)
Nishikawa, H., Fukunishi, S., Asai, A., Yokohama, K., Nishiguchi, S., & Higuchi, K. (2021) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2021.4989 · Cited by 256
Diabetes and Sarcopenic Obesity: Pathogenesis, Diagnosis, and Treatments
Wang, M., Tan, Y., Shi, Y., Wang, X., Liao, Z., & Wei, P. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00568 · Cited by 231
Sex Differences in Muscle Wasting
Anderson, L. J., Liu, H. M., & Garcia, J. M. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-70178-3_9 · Cited by 226
A positive association of vitamin D deficiency and sarcopenia in 50 year old women, but not men
Park, S., Ham, J.-O., & Lee, B.-K. (2013) · Clinical Nutrition · doi:10.1016/j.clnu.2013.09.016 · Cited by 103
Aging of the endocrine system and its potential impact on sarcopenia
Vitale, G., Cesari, M., & Mari, D. (2016) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2016.07.017 · Cited by 109
AlMohaisen, N., Gittins, M., Todd, C. J., Sremanakova, J., Sowerbutts, A. M., Aldossari, A., Almutairi, A. S., Jones, D. J., & Burden, S. T. (2022) · Nutrients · doi:10.3390/nu14081537 · Cited by 105
Managing Sarcopenia and Its Related-Fractures to Improve Quality of Life in Geriatric Populations
Hida, T. (2014) · Aging and Disease · doi:10.14336/ad.2014.0500226 · Cited by 77
Martı́n, A. I., Priego, T., & López‐Calderón, A. (2018) · Advances in experimental medicine and biology · doi:10.1007/978-981-13-1435-3_9 · Cited by 84
Sarcopenia in post-menopausal women: Is there any role for vitamin D?
Anagnostis, P. G., Dimopoulou, C., Karras, S. Ν., Lambrinoudaki, I. V., & Goulis, D. G. (2015) · Maturitas · doi:10.1016/j.maturitas.2015.03.014 · Cited by 77
Kovanen, V., Aukee, P., Kokko, K., Finni, T. J., Tarkka, I. M., Tammelin, T., Kujala, U. M., Sipilä, S., & Laakkonen, E. K. (2018) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0000000000001117 · Cited by 86
Self-citationPöllänen, E., Kangas, R., Horttanainen, M., Niskala, P., Kaprio, J. A., Butler-Browne, G. S., Mouly, V., Sipilä, S., & Kovanen, V. (2015) · Aging Cell · doi:10.1111/acel.12309 · Cited by 62
Self-citationAssessing the influence of age and gender on the phenotype of myotonic dystrophy type 2
Montagnese, F., Mondello, S., Wenninger, S., Kreß, W., & Schoser, B. G. H. (2017) · Journal of Neurology · doi:10.1007/s00415-017-8653-2 · Cited by 57
The Therapeutic Intervention of Sex Steroid Hormones for Sarcopenia
Huang, L., & Wang, J. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.739251 · Cited by 64
Biomarkers Profile of People With Sarcopenia: A Cross-sectional Analysis From UK Biobank
Petermann-Rocha, F. E., Gray, S. R., Pell, J. P., Celis-Morales, C. A., & Ho, F. K. W. (2020) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2020.05.005 · Cited by 56
Liu, Z., Guo, Y., & Zheng, C. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1375610 · Cited by 64
Piasecki, J., Inns, T. B., Bass, J. J., Scott, R., Stashuk, D. W., Phillips, B. E., Atherton, P. J., & Piasecki, M. (2020) · The Journal of Physiology · doi:10.1113/jp280679 · Cited by 50
Menopause and frailty: a scoping review
Ruan, H., Hu, J., Zhao, J., Tao, H., Chi, J., Niu, X., Zhang, J., & Wang, Y. (2020) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0000000000001612 · Cited by 51
Physical activity and fat-free mass during growth and in later life
Westerterp, K. R., Yamada, Y., Sagayama, H., Ainslie, P. N., Andersen, L. F., Anderson, L. J., Arab, L., Baddou, I., Bedu-Addo, K., Blaak, E. E., et al. (2021) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqab260 · Cited by 50
Regenerative Medicine Approaches for Age-Related Muscle Loss and Sarcopenia: A Mini-Review
Naranjo, J. D., Dziki, J. L., & Badylak, S. F. (2017) · Gerontology · doi:10.1159/000479278 · Cited by 49
Sellami, M., Bragazzi, N. L., Slimani, M., Hayes, L. D., Jabbour, G., Giorgio, A. D., & Dugué, B. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16101709 · Cited by 50
Impact of oestrogen deficiency and aging on tendon: concise review
Frizziero, A., Vittadini, F., Gasparre, G., & Masiero, S. (2019) · Muscles Ligaments and Tendons Journal · doi:10.32098/mltj.03.2014.11 · Cited by 44
Gender associated muscle-tendon adaptations to resistance training
McMahon, G. E., Morse, C. I., Winwood, K. L., Burden, A., & Onambélé-Pearson, G. L. (2018) · PLoS ONE · doi:10.1371/journal.pone.0197852 · Cited by 39
Every, D. W. V., D’Souza, A. C., & Phillips, S. M. (2024) · Exercise and Sport Sciences Reviews · doi:10.1249/jes.0000000000000346 · Cited by 40
Impact of oestrogen deficiency and aging on tendon: concise review
Frizziero, A. (2014) · Muscles Ligaments and Tendons Journal · doi:10.11138/mltj/2014.4.3.324 · Cited by 38
Divaris, E., Anagnostis, P. G., Gkekas, N. K., Kouidi, E. J., & Goulis, D. G. (2023) · Maturitas · doi:10.1016/j.maturitas.2023.05.006 · Cited by 39
Hormonal Influences on Skeletal Muscle Function in Women across Life Stages: A Systematic Review
Kodete, C. S., Thuraka, B., Pasupuleti, V., & Malisetty, S. (2024) · Muscles · doi:10.3390/muscles3030024 · Cited by 29
Su, X., Jin, K., Zhou, X. J., Zhang, Z., Zhang, C., Li, Y., Yang, M., Huang, X., Xu, S., Wei, Q., et al. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1125819 · Cited by 27
Park, K.-S., Kim, H., Kim, H., Lee, K.-I., Lee, S.-Y., & Kim, J. (2022) · Pharmaceuticals · doi:10.3390/ph15040390 · Cited by 23
Lumican, an Exerkine, Protects against Skeletal Muscle Loss
Cho, H. J., Lee, Y., Kim, D. A., Moon, S. A., Lee, S. E., Lee, S. H., & Koh, J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231710031 · Cited by 24
Naeyer, H. D., Lamon, S., Russell, A. P., Everaert, I., Spaey, A. D., Vanheel, B., Taes, Y., & Derave, W. (2014) · European Journal of Applied Physiology · doi:10.1007/s00421-013-2800-y · Cited by 24
Nunes, P. R. P., Barcelos, L. C., de Oliveira, A. A., Júnior, R. F., Martins, F. M., Resende, E. A. M. R., & Orsatti, F. L. (2017) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000001788 · Cited by 24
Combined sprint and resistance training abrogates age differences in somatotropic hormones
Sellami, M., Dhahbi, W., Hayes, L. D., Padulo, J., Rhibi, F., Djemail, H., & Chaouachi, A. (2017) · PLoS ONE · doi:10.1371/journal.pone.0183184 · Cited by 26
Novel individualized power training protocol preserves physical function in adult and older mice
Graber, T. G., Fandrey, K. R., & Thompson, L. V. (2019) · GeroScience · doi:10.1007/s11357-019-00069-z · Cited by 21
Maintenance of type 2 glycolytic myofibers with age by Mib1-Actn3 axis
Seo, J., Kang, J., Kim, Y. L., Jo, Y., Kim, J.-H., Hann, S., Park, J., Park, I., Park, H., Yoo, K., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-21621-6 · Cited by 21
Lee, M.-T., Wu, C., Chen, C.-W., Cheng, H.-L., Chen, C.-C., & Hsieh, Y. (2022) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2022.111002 · Cited by 20
Targeting muscle signaling pathways to minimize adverse effects of androgen deprivation
de Rooy, C., Grossmann, M., Zajac, J. D., & Cheung, A. S. (2015) · Endocrine Related Cancer · doi:10.1530/erc-15-0232 · Cited by 16
Menopause Transition: A Cross-Sectional Evaluation on Muscle Size and Quality
Smith‐Ryan, A. E., Hirsch, K. R., Cabre, H. E., Gould, L. M., Gordon, A. N., & Ferrando, A. A. (2023) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000003150 · Cited by 21
Ross, M., Lithgow, H., Hayes, L. D., & Florida-James, G. D. (2019) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-981-13-3681-2_12 · Cited by 16
Testosterone improves muscle function of the extensor digitorum longus in rats with sepsis
Wang, J., & Wu, T. (2020) · Bioscience Reports · doi:10.1042/bsr20193342 · Cited by 16
Perimenopausal women show modulation of excitatory and inhibitory neuromuscular mechanisms
Pesonen, H., Laakkonen, E. K., Hautasaari, P., Aukee, P., Kovanen, V., Sipilä, S., Finni, T. J., & Tarkka, I. M. (2021) · BMC Women s Health · doi:10.1186/s12905-021-01275-8 · Cited by 15
Self-citationAssociation between serum copper levels and muscle mass: results from NHANES 2011–2016
Chen, Z., Hu, D., Wu, D., Song, C., Sun, J., & Liu, W. (2023) · Environmental Science and Pollution Research · doi:10.1007/s11356-023-31599-x · Cited by 15
Impact of estrogen deficiency on diaphragm and leg muscle contractile function in female mdx mice
Vang, P., Baumann, C. W., Barok, R., Larson, A. A., Dougherty, B. J., & Lowe, D. A. (2021) · PLoS ONE · doi:10.1371/journal.pone.0249472 · Cited by 15
Load-induced human skeletal muscle hypertrophy: Mechanisms, myths, and misconceptions
Every, D. W. V., Lees, M. J., Wilson, B., Nippard, J., & Phillips, S. M. (2025) · Journal of sport and health science/Journal of Sport and Health Science · doi:10.1016/j.jshs.2025.101104 · Cited by 23
Huang, Y., Han, J., Gu, Q., Cai, Y., Li, J., Wang, S., Wang, S., Wang, R., & Liu, X. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.990100 · Cited by 15
Liu, S., Han, X., Li, J., Xie, X., Yang, Y., Jiang, W., Liu, L., & Liu, Z. (2023) · PeerJ · doi:10.7717/peerj.16652 · Cited by 12
Nan, W., Peng, Z., Yi, T., Ouyang, M., & Hu, J. (2024) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.117041 · Cited by 13
Predictors of presarcopenia in community-dwelling older adults: A 5-year longitudinal study
Kobayashi, K., Ando, K., Tsushima, M., Machino, M., Ota, K., Morozumi, M., Tanaka, S. A., Kanbara, S., Ishiguro, N., Hasegawa, Y., et al. (2018) · Modern Rheumatology · doi:10.1080/14397595.2018.1551171 · Cited by 13
Cushing, acromegaly, GH deficiency and tendons
Galdiero, M. (2014) · Muscles Ligaments and Tendons Journal · doi:10.11138/mltj/2014.4.3.329 · Cited by 11
Maternal protein malnutrition: effects on prostate development and adult disease
Rinaldi, J. D. C., dos Santos, S. A. A., Colombelli, K. T., Birch, L. A., Prins, G. S., Justulin, L. A., & Felisbino, S. L. (2018) · Journal of Developmental Origins of Health and Disease · doi:10.1017/s2040174418000168 · Cited by 11
Kim, M., Lee, J., Ha, J., Jo, K., Lim, D.-J., Lee, J.-M., Chang, S., Kang, M.-I., & Cha, B. Y. (2018) · Scientific Reports · doi:10.1038/s41598-017-17397-9 · Cited by 10
Liu, Z., Lei, T., Guo, Y., & Zheng, C. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1377666 · Cited by 8
Estrogen in skeletal muscle: metabolism, mechanisms, and exercise-induced changes
Feng, Y., & Shi, R. (2025) · Journal of Endocrinological Investigation · doi:10.1007/s40618-025-02726-x · Cited by 8
Zhang, J., Cheng, Y., Chen, C., Wang, Q., Yang, C., Qiu, J., Li, J., Liu, X., Zhang, Y., Liu, L., et al. (2023) · BMC Women s Health · doi:10.1186/s12905-023-02646-z · Cited by 8
Dynapenia and Sarcopenia During Female Midlife
Pérez-López, F. R. (2017) · Springer eBooks · doi:10.1007/978-3-319-59318-0_20 · Cited by 8
Ke, Y., Xu, J., Zhang, X., Guo, Q., & Zhu, Y. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2021.724649 · Cited by 7
Jin, M., Bok, M., Rho, H., Chon, J., & Lim, H. (2022) · Nutrition Research · doi:10.1016/j.nutres.2022.09.008 · Cited by 7
Estrogen regulates muscle bioenergetic signaling
Laakkonen, E. K., Soliymani, R., & Lalowski, M. M. (2018) · Aging · doi:10.18632/aging.101380 · Cited by 7
Ortiz-Navarro, B., Losa‐Reyna, J., Mihaiescu-Ion, V., García-Romero, J., de Albornoz-Gil, M. C., & Galán-Mercant, A. (2025) · JMIR Aging · doi:10.2196/67982 · Cited by 6
Physical Activity and Nutrition INfluences in Ageing: Current Findings from the PANINI Project
Whittaker, A. C., Asamane, E. A., Aunger, J. A., Bondarev, D., Cabbia, A., Doody, P., Gensous, N., Iadarola, B., Ramsey, K. A., Rodrigues, B., et al. (2019) · Advances in Geriatric Medicine and Research · doi:10.20900/agmr20190005 · Cited by 7
Le, G., Baumann, C. W., Warren, G. L., & Lowe, D. A. (2023) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00731.2022 · Cited by 6
Kim, M., & Sohn, C. (2016) · 대한지역사회영양학회지 · doi:10.5720/kjcn.2016.21.4.378 · Cited by 6
Xue, Z., Cao, J., Mou, J., Wang, R., & Liu, P. (2025) · Lipids in Health and Disease · doi:10.1186/s12944-025-02464-2 · Cited by 5
Matsumoto, S., Ochi, M., Akechi, Y., Takei, S., Senzaki, K., Okada, Y., Miura, S., Ochi, H., Igase, M., & Ohyagi, Y. (2022) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2022.104704 · Cited by 5
Gao, H., Hu, S., Hou, S., Song, Q., Shen, P., Liu, Y., & Ding, L. (2025) · Motor Control · doi:10.1123/mc.2024-0133 · Cited by 4
Wang, Y., Islam, R. M., Hussain, S. M., McNeil, J. J., & Davis, S. R. (2023) · The Journals of Gerontology Series A · doi:10.1093/gerona/glad287 · Cited by 5
Role of Sarcopenia in Diabetes Mellitus
Rhee, S. Y. (2013) · Journal of Korean Diabetes · doi:10.4093/jkd.2013.14.4.178 · Cited by 4
A review of the status of sarcopenia in elderly hospitalized patients
Xian, X., Zhang, J., & Yang, H. (2025) · Medicine · doi:10.1097/md.0000000000043365 · Cited by 3
Tan, L. F., Jin, A., Ying, A. F., Pan, A., Teng, G. G., & Koh, W. (2025) · BMC Geriatrics · doi:10.1186/s12877-025-06595-0 · Cited by 3
Sex hormones regulate neuromuscular junction structure, plasticity, and disease vulnerability
Qaisar, R., Ahmad, F., & Karim, A. (2026) · Discover Neuroscience · doi:10.1186/s13064-026-00241-0 · Cited by 3
Sex Differences in the Long-Term Consequences of Stroke
Stewart, C. E., Branyan, T. E., Sampath, D., & Sohrabji, F. (2022) · Current topics in behavioral neurosciences · doi:10.1007/7854_2022_311 · Cited by 4
Associated factors of low muscle mass in community-dwelling patients with type 2 diabetes
Lin, C., Yu, N., Wu, H., Liu, Y.-C., Chiu, I.-Y., Lin, W.-C., & Chien, W. (2024) · Medicine · doi:10.1097/md.0000000000038629 · Cited by 3
Ellis, L. (2025) · Cambridge University Press eBooks · doi:10.1017/9781009581028 · Cited by 2
Kochi, M. N., Marques, N. R., da, G. D. C., & Julia, C. (2015) · Journal of Osteoporosis and Physical Activity · doi:10.4172/2329-9509.1000151 · Cited by 3
Encabo, P. G., Valadés, D., de Cos, A. I., García‐Honduvilla, N., & Pérez‐López, A. (2019) · Science & Sports · doi:10.1016/j.scispo.2018.09.012 · Cited by 3
Mariano, J. M., Joca, H. C., Kallenbach, J. G., Ranu, N., Ochala, J., Ward, C. W., & Kontrogianni‐Konstantopoulos, A. (2025) · JCI Insight · doi:10.1172/jci.insight.182471 · Cited by 3
Preventive Strategies to Reduce Sarcopenia Risk During GLP-1-Based Anti-Obesity Therapy
Belančić, A., Skroče, K., Gkrinia, E. M. M., Glavić, M. M., & Kwok, M. K. (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15155870 · Cited by 3
Relevant Factors for Sarcopenia in Hyperthyroidism Patients
Liu, Z., Xia, F.-F., Zhao, X., & Zhou, D. (2018) · OALib · doi:10.4236/oalib.1104620 · Cited by 1
Granic, A., Cooper, R., Hurst, C., Hillman, S. J., Dodds, R. M., Witham, M. D., & Sayer, A. A. (2024) · European Geriatric Medicine · doi:10.1007/s41999-024-01119-2 · Cited by 2
Masik, N. P., & Kalandey, K. Y. (2019) · PAIN JOINTS SPINE · doi:10.22141/2224-1507.9.2.2019.172123 · Cited by 2
The Role of Ultrasound Imaging of Musculotendinous Structures in the Elderly Population
Carrão, L., Santos, R. M., Espanha, M., Armada-da-Silva, P. A. S., Amaral, A. P., Amado, S., Almeida, H. A., Pascoal‐Faria, P., & Veloso, A. (2018) · Lecture notes in computational vision and biomechanics · doi:10.1007/978-3-319-71574-2_3 · Cited by 2
Hormone therapy and sarcopenia: implications for the prevention of frailty as women age
Kaunitz, A. M., Pinkerton, J. V., & Manson, J. E. (2020) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0000000000001541 · Cited by 2
Zoledronic acid improves bone quality and muscle function in a high bone turnover statePreprint
Trivedi, T., Manaa, M., John, S. K., Reiken, S. R., Murthy, S., Pagnotti, G. M., Dole, N. S., She, Y., Suresh, S., Hain, B. A., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.06.01.543305 · Cited by 2
Zhang, H.-M., & Yu, L. (2023) · journal of nutritional oncology · doi:10.1097/jn9.0000000000000016 · Cited by 1
Resistance training-induced dihydrotestosterone is blunted in aging rat skeletal muscle
Hung, Y., Ishigami, A., & Machida, S. (2025) · The Journal of Physiological Sciences · doi:10.1016/j.jphyss.2025.100019 · Cited by 1
Zhang, Y., Gao, X., Yu, R., Zhang, D., Wang, Y., Wang, J., & Chen, X. (2025) · Biological Trace Element Research · doi:10.1007/s12011-025-04729-4 · Cited by 1
Xiong, J., Yin, L., Li, X., Wang, H., & Yu, B. (2025) · Aging Clinical and Experimental Research · doi:10.1007/s40520-025-03116-2 · Cited by 1
He, B., & Yu, X. (2025) · Frontiers in Physiology · doi:10.3389/fphys.2025.1579649 · Cited by 1
Jeong, Y., Kim, M.-S., Shin, S., Han, A., Seo, G., & Sohn, C. (2016) · 대한지역사회영양학회지 · doi:10.5720/kjcn.2016.21.3.284 · Cited by 1
Age and Running: Children and Adolescents, Elder People
Piedade, S. R., Viana, L. O., & Arruda, B. P. L. (2022) · Springer eBooks · doi:10.1007/978-3-662-65064-6_5 · Cited by 1
Nelson, C. R. (2014) · e-Publications@Marquette (Marquette University)
Effects of hormonal contraceptives on physical performance and body composition
Myllyaho, M. M. (2016) · Jyväskylä University Digital Archive (University of Jyväskylä)
Sex Hormone Influenced Differences in Skeletal Muscle Responses to Aging and Exercise
Brown, M., & Tiidus, P. M. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802388-4.00010-0
Effects of Treadmill Exercise on Muscle Transcription Factors and TGF-β1 Expression in Aged Rats
Kim, Y., Yoon, J.-H., & Kim, Y.-M. (2017) · 한국체육학회지 · doi:10.23949/kjpe.2017.01.56.1.49
Graber, T. G. (2015) · University of Minnesota Digital Conservancy (University of Minnesota)
Ormoni e plasticità delle fibre del muscolo scheletrico. Ruolo nella patogenesi della sarcopenia
Galfano, V., & Donini, L. M. (2018) · L Endocrinologo · doi:10.1007/s40619-018-00470-4
Exercise and Nutrition to Counter Age-Related Decrements in Muscle Health and Function
Trautman, K. A. (2020) · NDSU Repository (North Dakota State University)
Wullems, J. A., Degens, H., Morse, C. I., & Onambélé-Pearson, G. L. (2024) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0000000000002356
Metadata
- Authors
- Sipilä, S., Narici, M., Kjaer, M., Pöllänen, E., Atkinson, R. A., Hansen, M., & Kovanen, V.
- Affiliations
- University of Jyväskylä (FI)
- University of Nottingham (GB)
- Manchester Academic Health Science Centre (GB)
- Aarhus University (DK)
- Corresponding author
- Sipilä, Sarianna
- Venue
- Biogerontology
- Published
- 2013-05-01
- Volume
- 14
- Issue
- 3
- Pages
- 231-245
- ISSN
- 1389-5729 (ISSN-L)
- 1573-6768
- OpenAlex
- W2168506543
- Cited by
- 106
- References
- 81
- Citations by year
- 2026: 7 · 2025: 13 · 2024: 8 · 2023: 11 · 2022: 10 · 2021: 6 · 2020: 7 · 2019: 8 · 2018: 11 · 2017: 7 · 2016: 5 · 2015: 6 · 2014: 5 · 2013: 2
- FWCI
- 0.88
- Type
- journal article
- Language
- en
- Open access
- green
- zenodo.org
- Licence
- other-oa
- www.springer.com/tdm (tdm)
- Locations
- Biogerontology (publishedVersion)
- PubMed (publishedVersion)
- Research Explorer (The University of Manchester) (publishedVersion)
- Padua Research Archive (University of Padova) (submittedVersion)
- Zenodo (CERN European Organization for Nuclear Research) (submittedVersion, other-oa)
- Funders
- Academy of Finland
- Medical Research Council (MR/K00414X/1)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
- Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
- Keywords
- sex hormones, skeletal muscle weakness, sarcopenia, aging, hormone replacement therapy, estrogen, testosterone, postmenopausal women, muscle mass loss, resistance training, insulin-like growth factor I, adipokines, interleukin-6, tendons, connective tissue, steroidogenic enzymes
- MeSH terms
- Aging, Estrogens, Female, Humans, Male, Gonadal Steroid Hormones, Testosterone, Muscle, Skeletal, Muscle Weakness, Hormone Replacement Therapy
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
