The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Tumour vascularization: sprouting angiogenesis and beyond
Open accessAbstract
Tumour angiogenesis is a fast growing domain in tumour biology. Many growth factors and mechanisms have been unravelled. For almost 30 years, the sprouting of new vessels out of existing ones was considered as an exclusive way of tumour vascularisation. However, over the last years several additional mechanisms have been identified. With the discovery of the contribution of intussusceptive angiogenesis, recruitment of endothelial progenitor cells, vessel co-option, vasculogenic mimicry and lymphangiogenesis to tumour growth, anti-tumour targeting strategies will be more complex than initially thought. This review highlights these processes and intervention as a potential application in cancer therapy. It is concluded that future anti-vascular therapies might be most beneficial when based on multimodal anti-angiogenic, anti-vasculogenic mimicry and anti-lymphangiogenic strategies.
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Cites
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BackgroundEndostatin: an endogenous inhibitor of angiogenesis and tumor growth
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Cited by
Angiogenic signaling pathways and anti-angiogenic therapy for cancer
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Tumor and its microenvironment: A synergistic interplay
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Resistance Mechanisms to Anti-angiogenic Therapies in Cancer
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Metadata
- Authors
- Hillen, F., & Griffioen, A. W.
- Venue
- Cancer and Metastasis Reviews
- Published
- 2007-08-24
- Volume
- 26
- Issue
- 3-4
- Pages
- 489-502
- ISSN
- 0167-7659 (ISSN-L)
- 1573-7233
- OpenAlex
- W1984383995
- Cited by
- 583
- References
- 11
- FWCI
- 1.27
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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