Endothelial/Pericyte Interactions

Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis

Maisonpierre, P. C., Suri, C., Jones, P. F., Bartunkova, S., Wiegand, S. J., Radziejewski, C., Compton, D., McClain, J., Aldrich, T. H., Papadopoulos, N., et al. (1997) · Science · doi:10.1126/science.277.5322.55 · Cited by 3,570 · see citing works

Requisite Role of Angiopoietin-1, a Ligand for the TIE2 Receptor, during Embryonic Angiogenesis

Suri, C., Jones, P. F., Patan, S., Bartunkova, S., Maisonpierre, P. C., Davis, S. H., Sato, T. N., & Yancopoulos, G. D. (1996) · Cell · doi:10.1016/s0092-8674(00)81813-9 · Cited by 2,831 · see citing works

Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice

Lindahl, P., Johansson, B. R., Levéen, P., & Betsholtz, C. (1997) · Science · doi:10.1126/science.277.5323.242 · Cited by 2,226 · see citing works

Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

Joutel, A., Corpechot, C., Ducros, A., Vahedi, K., Chabriat, H., Mouton, P., Alamowitch, S., Domenga, V., Cécillion, M., Maréchal, E., et al. (1996) · Nature · doi:10.1038/383707a0 · Cited by 2,068 · see citing works

Isolation of Angiopoietin-1, a Ligand for the TIE2 Receptor, by Secretion-Trap Expression Cloning

Davis, S., Aldrich, T. H., Jones, P. F., Acheson, A., Compton, D. L., Jain, V., Ryan, T. E., Bruno, J., Radziejewski, C., Maisonpierre, P. C., et al. (1996) · Cell · doi:10.1016/s0092-8674(00)81812-7 · Cited by 1,989 · see citing works

Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

Sato, T. N., Tozawa, Y., Deutsch, U., Wolburg‐Buchholz, K., Fujiwara, Y., Gendron‐Maguire, M., Gridley, T., Wolburg, H., Risau, W., & Qin, Y. (1995) · Nature · doi:10.1038/376070a0 · Cited by 1,821 · see citing works

Role of PDGF-B and PDGFR-β in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse

Hellström, M., Kalén, M., Lindahl, P., Abramsson, A., & Betsholtz, C. (1999) · Development · doi:10.1242/dev.126.14.3047 · Cited by 1,702 · see citing works

Endoglin, a TGF-β binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1

McAllister, K. A., Grogg, K. M., Johnson, D. W., Gallione, C. J., Baldwin, M. A., Jackson, C. E., Helmbold, E. A., Markel, D. S., McKinnon, W. C., Murrel, J., et al. (1994) · Nature Genetics · doi:10.1038/ng1294-345 · Cited by 1,475 · see citing works

Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

Bergers, G., Song, S., Meyer-Morse, N., Bergsland, E. K., & Hanahan, D. (2003) · Journal of Clinical Investigation · doi:10.1172/jci17929 · Cited by 1,361 · see citing works

Leakage-Resistant Blood Vessels in Mice Transgenically Overexpressing Angiopoietin-1

Thurston, G., Suri, C., Smith, K., McClain, J., Sato, T. T., Yancopoulos, G. D., & McDonald, D. M. (1999) · Science · doi:10.1126/science.286.5449.2511 · Cited by 1,350 · see citing works

Edg-1, the G protein–coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation

Liu, Y., Wada, R., Yamashita, T., Mi, Y., Deng, C., Hobson, J. P., Rosenfeldt, H. M., Nava, V. E., Chae, S.-S., Lee, M.-J., et al. (2000) · Journal of Clinical Investigation · doi:10.1172/jci10905 · Cited by 1,144 · see citing works

Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities.Preprint

Levéen, P., Pekny, M., Gebré‐Medhin, S., Swolin, B., Larsson, E., & Betsholtz, C. (1994) · Genes & Development · doi:10.1101/gad.8.16.1875 · Cited by 1,130 · see citing works

Balancing the activation state of the endothelium via two distinct TGF‐β type I receptors

Goumans, M., Valdimarsdóttir, G., Itoh, S., Rosendahl, A., Sideras, P., & ten Dijke, P. (2002) · The EMBO Journal · doi:10.1093/emboj/21.7.1743 · Cited by 1,127 · see citing works

Mutations in the activin receptor–like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2

Johnson, D. W., Berg, J. N., Baldwin, M. A., Gallione, C. J., Marondel, I., Yoon, S.-H., Stenzel, T. T., Speer, M. C., Pericak‐Vance, M. A., Diamond, A. G., et al. (1996) · Nature Genetics · doi:10.1038/ng0696-189 · Cited by 1,113 · see citing works

Lack of Pericytes Leads to Endothelial Hyperplasia and Abnormal Vascular Morphogenesis

Hellström, M., Gerhardt, H., Kalén, M., Li, X., Eriksson, U., Wolburg, H., & Betsholtz, C. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.153.3.543 · Cited by 1,103 · see citing works

Endothelial-pericyte interactions in angiogenesis

Gerhardt, H., & Betsholtz, C. (2003) · Cell and Tissue Research · doi:10.1007/s00441-003-0745-x · Cited by 1,060 · see citing works

Bone Formation and Inflammation in Cardiac Valves

Mohler, E. R., Gannon, F. H., Reynolds, C. A., Zimmerman, R. A., Keane, M. G., & Kaplan, F. S. (2001) · Circulation · doi:10.1161/01.cir.103.11.1522 · Cited by 1,053 · see citing works

Defective haematopoiesis and vasculogenesis in transforming growth factor-β1 knock out mice

Dickson, M. C., Martin, J. S., Cousins, F. M., Kulkarni, A. B., Karlsson, S., & Akhurst, R. J. (1995) · Development · doi:10.1242/dev.121.6.1845 · Cited by 1,029 · see citing works

Angiopoietin-2 Is Required for Postnatal Angiogenesis and Lymphatic Patterning, and Only the Latter Role Is Rescued by Angiopoietin-1

Gale, N. W., Thurston, G., Hackett, S. F., Renard, R. A., Wang, Q., McClain, J., Martin, C., Witte, C. L., Witte, M. H., Jackson, D. G., et al. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00217-4 · Cited by 1,017 · see citing works

Vascular Endothelial Cell Adherens Junction Assembly and Morphogenesis Induced by Sphingosine-1-Phosphate

Lee, M.-J., Thangada, S., Claffey, K. P., Ancellin, N., Liu, C. H., Kluk, M., Volpi, M., Sha'afi, R. I., & Hla, T. (1999) · Cell · doi:10.1016/s0092-8674(00)81661-x · Cited by 1,003 · see citing works

Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.Preprint

Soriano, P. M. (1994) · Genes & Development · doi:10.1101/gad.8.16.1888 · Cited by 988 · see citing works

Abnormalities in Pericytes on Blood Vessels and Endothelial Sprouts in Tumors

Morikawa, S., Bałuk, P., Kaidoh, T., Haskell, A., Jain, R. K., & McDonald, D. M. (2002) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)64920-6 · Cited by 987 · see citing works

Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo.

Dumont, D. J., Gradwohl, G., Fong, G. H., Puri, M. C., Gertsenstein, M., Auerbach, A., & Breitman, M. L. (1994) · Genes & Development · doi:10.1101/gad.8.16.1897 · Cited by 985 · see citing works

Notch signaling is required for arterial-venous differentiation during embryonic vascular development

Lawson, N. D., Scheer, N., Pham, V. N., Kim, C., Chitnis, A. B., Campos‐Ortega, J. A., & Weinstein, B. M. (2001) · Development · doi:10.1242/dev.128.19.3675 · Cited by 915 · see citing works

Defective Angiogenesis in Mice Lacking Endoglin

Li, D. Y., Sorensen, L. K., Brooke, B. S., Urness, L. D., Davis, E. C., Taylor, D. G., Boak, B. B., & Wendel, D. P. (1999) · Science · doi:10.1126/science.284.5419.1534 · Cited by 853 · see citing works

Activin receptor-like kinase 1 modulates transforming growth factor-β1 signaling in the regulation of angiogenesis

Oh, S. P., Seki, T., Goss, K. A., Imamura, T., Yi, Y., Donahoe, P. K., Li, L., Miyazono, K., ten Dijke, P., Kim, S., et al. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.6.2626 · Cited by 852 · see citing works

Increased Vascularization in Mice Overexpressing Angiopoietin-1

Suri, C., McClain, J., Thurston, G., McDonald, D. M., Zhou, H., Oldmixon, E. H., Sato, T. N., & Yancopoulos, G. D. (1998) · Science · doi:10.1126/science.282.5388.468 · Cited by 818 · see citing works

Vascular Dysmorphogenesis Caused by an Activating Mutation in the Receptor Tyrosine Kinase TIE2

Vikkula, M., Boon, L. M., Carraway, K. L., Calvert, J. T., Diamonti, A. J., Goumnerov, B. C., Pasyk, K. A., Marchuk, D. A., Warman, M. L., Cantley, L. C., et al. (1996) · Cell · doi:10.1016/s0092-8674(00)81814-0 · Cited by 797 · see citing works

PDGF, TGF-β, and Heterotypic Cell–Cell Interactions Mediate Endothelial Cell–induced Recruitment of 10T1/2 Cells and Their Differentiation to a Smooth Muscle Fate

Hirschi, K. K., Rohovsky, S. A., & D'Amore, P. A. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.141.3.805 · Cited by 796 · see citing works

Cellular abnormalities of blood vessels as targets in cancer

Bałuk, P., Hashizume, H., & McDonald, D. M. (2004) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2004.12.005 · Cited by 784 · see citing works

An activated form of transforming growth factor beta is produced by cocultures of endothelial cells and pericytes.

Orlidge, A., Saunders, K. B., Smith, S. R., & D'Amore, P. A. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.12.4544 · Cited by 752 · see citing works

The Tie-2 ligand Angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies

Fiedler, U., Scharpfenecker, M., Koidl, S., Hegen, A., Grunow, V., Schmidt, J. M., Kriz, W., Thurston, G., & Augustin, H. G. (2004) · Blood · doi:10.1182/blood-2003-10-3685 · Cited by 742 · see citing works

Role of tissue factor in embryonic blood vessel development

Carmeliet, P., Mackman, N., Moons, L., Luther, T., Gressèns, P., Vlaenderen, L. V., Demunck, H., Kasper, M. E., Breier, G., Evrard, P., et al. (1996) · Nature · doi:10.1038/383073a0 · Cited by 669 · see citing works

Pericytes and the Pathogenesis of Diabetic Retinopathy

Hammes, H., Lin, J., Renner, O., Shani, M., Lundqvist, A., Betsholtz, C., Brownlee, M., & Deutsch, U. (2002) · Diabetes · doi:10.2337/diabetes.51.10.3107 · Cited by 669 · see citing works

Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity

You, L., Lin, F., Lee, C. T., DeMayo, F. J., Tsai, M., & Tsai, S. Y. (2005) · Nature · doi:10.1038/nature03511 · Cited by 664 · see citing works

Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wallPreprint

Lindblom, P., Gerhardt, H., Liebner, S., Abramsson, A., Enge, M., Hellström, M., Bäckström, G., Fredriksson, S., Landegren, U. D., Nyström, H. C., et al. (2003) · Genes & Development · doi:10.1101/gad.266803 · Cited by 659 · see citing works

The cephalic neural crest provides pericytes and smooth muscle cells to all blood vessels of the face and forebrain

Etchevers, H. C., Vincent, C., Douarin, N. M. L., & F. Couly, G. (2001) · Development · doi:10.1242/dev.128.7.1059 · Cited by 657 · see citing works

Endoglin promotes endothelial cell proliferation and TGF‐β/ALK1 signal transduction

Lebrin, F., Goumans, M., Jonker, L., Carvalho, R. L. C., Valdimarsdóttir, G., Thorikay, M., Mummery, C. L., Arthur, H. M., & ten Dijke, P. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600386 · Cited by 653 · see citing works

Pericyte physiology

Sheṕro, D., & Morel-Laurens, N. (1993) · The FASEB Journal · doi:10.1096/fasebj.7.11.8370472 · Cited by 652 · see citing works

TGF-β Receptor Type II Deficiency Results in Defects of Yolk Sac Hematopoiesis and Vasculogenesis

Oshima, M., Oshima, H., & Taketo, M. M. (1996) · Developmental Biology · doi:10.1006/dbio.1996.0259 · Cited by 651 · see citing works

The Notch target genes Hey1 and Hey2 are required for embryonic vascular developmentPreprint

Fischer, A., Schumacher, N., Maier, M., Sendtner, M., & Gessler, M. (2004) · Genes & Development · doi:10.1101/gad.291004 · Cited by 651 · see citing works

Extensive Vasculogenesis, Angiogenesis, and Organogenesis Precede Lethality in Mice Lacking All αv Integrins

Bader, B., Rayburn, H., Crowley, D. G., & Hynes, R. O. (1998) · Cell · doi:10.1016/s0092-8674(00)81618-9 · Cited by 649 · see citing works

Roles of PDGF in animal development

Hoch, R. V., & Soriano, P. M. (2003) · Development · doi:10.1242/dev.00721 · Cited by 588 · see citing works

Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis

Petrova, T. V., Kärpänen, T., Norrmén, C., Mellor, R. H., Tamakoshi, T., Finegold, D. N., Ferrell, R. E., Kerjaschki, D., Mortimer, P. S., Ylä‐Herttuala, S., et al. (2004) · Nature Medicine · doi:10.1038/nm1094 · Cited by 587 · see citing works

The pericyte—A review

Sims, D. (1986) · Tissue and Cell · doi:10.1016/0040-8166(86)90026-1 · Cited by 582 · see citing works

Vascular Pericytes Express Osteogenic Potential In Vitro and In Vivo

Doherty, M. J., Ashton, B. A., Walsh, S., Beresford, J. N., Grant, M. E., & Canfield, A. E. (1998) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1998.13.5.828 · Cited by 566 · see citing works

Abnormal angiogenesis but intact hematopoietic potential in TGF‐β type I receptor‐deficient mice

Larsson, J., Goumans, M., Sjöstrand, L. J., van Rooijen, M. A., Ward, D., Levéen, P., Xu, X., ten Dijke, P., Mummery, C. L., & Karlsson, S. (2001) · The EMBO Journal · doi:10.1093/emboj/20.7.1663 · Cited by 563 · see citing works

Notch3 is required for arterial identity and maturation of vascular smooth muscle cellsPreprint

Domenga, V., Fardoux, P., Lacombe, P. M., Monet, M., Maciazek, J., Krebs, L. T., Klonjkowski, B., Berrou, E., Mericskay, M., Li, Z., et al. (2004) · Genes & Development · doi:10.1101/gad.308904 · Cited by 537 · see citing works

Cell Type-Specific Expression of Angiopoietin-1 and Angiopoietin-2 Suggests a Role in Glioblastoma Angiogenesis

Stratmann, A., Risau, W., & Plate, K. H. (1998) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)65733-1 · Cited by 486 · see citing works

Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors

Abramsson, A., Lindblom, P., & Betsholtz, C. (2003) · Journal of Clinical Investigation · doi:10.1172/jci18549 · Cited by 478 · see citing works

A murine model of hereditary hemorrhagic telangiectasia

Bourdeau, A., Dumont, D., & Letarte, M. (1999) · Journal of Clinical Investigation · doi:10.1172/jci8088 · Cited by 471 · see citing works

Chondrogenic and Adipogenic Potential of Microvascular Pericytes

Farrington, C., Crofts, N. J., Doherty, M. J., Ashton, B. A., Griffin-Jones, C., & Canfield, A. E. (2004) · Circulation · doi:10.1161/01.cir.0000144457.55518.e5 · Cited by 470 · see citing works

Pericytes: Cell Biology and Pathology

Allt, G., & Lawrenson, J. G. (2001) · Cells Tissues Organs · doi:10.1159/000047855 · Cited by 451 · see citing works

Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors.

Pietras, K., Östman, A., SJÖQUIST, M., Buchdunger, E., Reed, R. K., Heldin, C., & Rubin, K. (2001) · PubMed · Cited by 449 · see citing works

Characterization of the activation of latent TGF-beta by co-cultures of endothelial cells and pericytes or smooth muscle cells: a self-regulating system.

Sato, Y., Tsuboi, R., Lyons, R., Moses, H., & Rifkin, D. B. (1990) · The Journal of cell biology · doi:10.1083/jcb.111.2.757 · Cited by 444 · see citing works

Arteriovenous malformations in mice lacking activin receptor-like kinase-1

Urness, L. D., Sorensen, L. K., & Li, D. Y. (2000) · Nature Genetics · doi:10.1038/81634 · Cited by 443 · see citing works

Insight into the physiological functions of PDGF through genetic studies in mice

Betsholtz, C. (2004) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2004.03.005 · Cited by 437 · see citing works

Endoglin, an Ancillary TGFβ Receptor, Is Required for Extraembryonic Angiogenesis and Plays a Key Role in Heart Development

Arthur, H. M., Ure, J. M., Smith, A. J. H., Renforth, G. L., Wilson, D. I., Torsney, E., Charlton, R., Parums, D. V., Jowett, T., Marchuk, D. A., et al. (2000) · Developmental Biology · doi:10.1006/dbio.1999.9534 · Cited by 436 · see citing works

Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects

Chang, H., Huylebroeck, D., Verschueren, K., Guo, Q., Matzuk, M. M., & Zwijsen, A. (1999) · Development · doi:10.1242/dev.126.8.1631 · Cited by 435 · see citing works

Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy.

Pietras, K., Rubin, K., Sjöblom, T., Buchdunger, E., Sjöquist, M., Heldin, C., & Östman, A. (2002) · PubMed · Cited by 432 · see citing works

Chemotactic Properties of Angiopoietin-1 and -2, Ligands for the Endothelial-specific Receptor Tyrosine Kinase Tie2

Witzenbichler, B., Maisonpierre, P. C., Jones, P. F., Yancopoulos, G. D., & Isner, J. M. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.29.18514 · Cited by 429 · see citing works

The Sphingosine-1-phosphate Receptors S1P1, S1P2, and S1P3 Function Coordinately during Embryonic Angiogenesis

Kono, M., Mi, Y., Liu, Y., Sasaki, T., Allende, M. L., Wu, Y., Yamashita, T., & Proia, R. L. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m403937200 · Cited by 415 · see citing works

Endothelium‐specific platelet‐derived growth factor‐B ablation mimics diabetic retinopathy

Enge, M., Bjarnegård, M., Gerhardt, H., Gustafsson, E., Kalén, M., Asker, N., Hammes, H., Shani, M., Fässler, R., & Betsholtz, C. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf418 · Cited by 402 · see citing works

G-protein-coupled receptor S1P1 acts within endothelial cells to regulate vascular maturation

Allende, M. L., Yamashita, T., & Proia, R. L. (2003) · Blood · doi:10.1182/blood-2003-02-0460 · Cited by 390 · see citing works

Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells

Rajantie, I., Ilmonen, M., Alminaite, A., Özerdem, U., Alitalo, K. K., & Salvén, P. (2004) · Blood · doi:10.1182/blood-2004-01-0336 · Cited by 390 · see citing works

Angiogenesis defects and mesenchymal apoptosis in mice lacking SMAD5

Yang, X. Y., Castilla, L. H., Xu, X., Li, C., Gotay, J., Weinstein, M. B., Liu, P. P., & Deng, C. (1999) · Development · doi:10.1242/dev.126.8.1571 · Cited by 388 · see citing works

The LKLF transcription factor is required for normal tunica media formation and blood vessel stabilization during murine embryogenesisPreprint

Kuo, C. T., Veselits, M., Barton, K., Lu, M. M., Clendenin, C. J., & Leiden, J. M. (1997) · Genes & Development · doi:10.1101/gad.11.22.2996 · Cited by 369 · see citing works

Fli-1 Is Required for Murine Vascular and Megakaryocytic Development and Is Hemizygously Deleted in Patients with Thrombocytopenia

Hart, A., Melet, F., Grossfeld, P., Chien, K., Jones, C., Tunnacliffe, A., Favier, R., & Bernstein, A. (2000) · Immunity · doi:10.1016/s1074-7613(00)00017-0 · Cited by 369 · see citing works

Endothelium-specific ablation of PDGFB leads to pericyte loss and glomerular, cardiac and placental abnormalities

Bjarnegård, M., Enge, M., Norlin, J., Gustafsdottir, S., Fredriksson, S., Abramsson, A., Takemoto, M., Gustafsson, E., Fässler, R., & Betsholtz, C. (2004) · Development · doi:10.1242/dev.01080 · Cited by 368 · see citing works

Brain pericytes contribute to the induction and up-regulation of blood–brain barrier functions through transforming growth factor-β production

Dohgu, S., Takata, F., Yamauchi, A., Nakagawa, S., Egawa, T., Naito, M., Tsuruo, T., Sawada, Y., Niwa, M., & Kataoka, Y. (2005) · Brain Research · doi:10.1016/j.brainres.2005.01.027 · Cited by 350 · see citing works

Heparin-binding EGF-like growth factor and ErbB signaling is essential for heart function

Iwamoto, R., Yamazaki, S., Asakura, M., Takashima, S., Hasuwa, H., Miyado, K., Adachi, S., Kitakaze, M., Hashimoto, K., Raab, G., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0537588100 · Cited by 341 · see citing works

A pericyte‐derived angiopoietin‐1 multimeric complex induces occludin gene expression in brain capillary endothelial cells through Tie‐2 activation in vitro

Hori, S., Ohtsuki, S., Hosoya, K., Nakashima, E., & Terasaki, T. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02343.x · Cited by 341 · see citing works

Angiopoietin-2 Causes Pericyte Dropout in the Normal Retina

Hammes, H., Lin, J., Wagner, P., Feng, Y., Hagen, F. V., Krzizok, T. H., Renner, O., Breier, G., Brownlee, M., & Deutsch, U. (2004) · Diabetes · doi:10.2337/diabetes.53.4.1104 · Cited by 341 · see citing works

Embryonic Endothelial Cells Transdifferentiate Into Mesenchymal Cells Expressing Smooth Muscle Actins In Vivo and In Vitro

DeRuiter, M. C., Poelmann, R. E., van Munsteren, J. C., Mironov, V., Markwald, R. R., & Groot, A. C. G. (1997) · Circulation Research · doi:10.1161/01.res.80.4.444 · Cited by 332 · see citing works

Requirement of the MADS-box transcription factor MEF2C for vascular development

Lin, Q., Lu, J., Yanagisawa, H., Webb, R. C., Lyons, G. E., Richardson, J. A., & Olson, E. N. (1998) · Development · doi:10.1242/dev.125.22.4565 · Cited by 309 · see citing works

Role of the CNS microvascular pericyte in the blood-brain barrier

Balabanov, R. D., & Dore‐Duffy, P. (1998) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19980915)53:6 · Cited by 304 · see citing works

Developmental Biology of the Vascular Smooth Muscle Cell: Building a Multilayered Vessel Wall

Hungerford, J. E., & Little, C. (1999) · Journal of Vascular Research · doi:10.1159/000025622 · Cited by 293 · see citing works

Akt-Mediated Phosphorylation of the G Protein-Coupled Receptor EDG-1 Is Required for Endothelial Cell Chemotaxis

Lee, M.-J., Thangada, S., Paik, J.-H., Sapkota, G. P., Ancellin, N., Chae, S.-S., Wu, M.-T., Morales‐Ruiz, M., Sessa, W. C., Alessi, D. R., et al. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00324-0 · Cited by 288 · see citing works

Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells

Uemura, A., Ogawa, M., Hirashima, M., Fujiwara, T., Koyama, S., Takagi, H., Honda, Y., Wiegand, S. J., Yancopoulos, G. D., & Nishikawa, S.-I. (2002) · Journal of Clinical Investigation · doi:10.1172/jci15621 · Cited by 282 · see citing works

Ultrastructure and Three-Dimensional Organization of the Telangiectases of Hereditary Hemorrhagic Telangiectasia

Braverman, I. M., Keh, A., & Jacobson, B. S. (1990) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12555569 · Cited by 279 · see citing works

Growth inhibition of dermatofibrosarcoma protuberans tumors by the platelet-derived growth factor receptor antagonist STI571 through induction of apoptosis.

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Sphingosine 1-phosphate receptor regulation of N-cadherin mediates vascular stabilizationPreprint

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