Cited by 152Diabetes, Cardiovascular Risks, and LipoproteinsSex and Gender in HealthcareCardiovascular Disease and Adiposity

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Metabolic Syndrome: Does it Differ Between Women and Men?

Rochlani, Yogita, Pothineni, Naga Venkata, Mehta, Jawahar L.·2015·Cardiovascular Drugs and Therapy

DOI 10.1007/s10557-015-6593-6

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Abstract

Cardiovascular disease represents a massive healthcare burden worldwide. Gender differences in the pathophysiology, presentation and prognosis of cardiovascular disease have been described in the literature. Metabolic syndrome, characterized by a cluster of metabolic abnormalities is associated with increased risk for type 2 diabetes mellitus and atherosclerotic cardiovascular disease. With the global obesity epidemic, the prevalence of metabolic syndrome is rising rapidly in the developed as well as developing world. However, there is considerable variation in the prevalence based on geography, age, sex and, definition used for diagnosis. Data on gender related differences in metabolic syndrome is relatively scarce. Here, we aim to review the gender differences in epidemiology and pathophysiology of metabolic syndrome as well as its individual components. Knowledge of gender differences in metabolic syndrome can help design gender specific preventative and therapeutic strategies that will have a positive impact on overall population health.

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Authors: Rochlani, Y., Pothineni, N. V., & Mehta, J. L.
Affiliations: University of Arkansas for Medical Sciences (US)
Corresponding author: Rochlani, Yogita
ORCID: Rochlani, Yogita
Pothineni, Naga Venkata
Mehta, Jawahar L.
Venue: Cardiovascular Drugs and Therapy
Publisher: Springer Science and Business Media LLC
Published: 2015-05-21
Volume: 29
Issue: 4
Pages: 329-338
ISSN: 0920-3206 (ISSN-L)
1573-7241
DOI: 10.1007/s10557-015-6593-6
OpenAlex: W329676011
Cited by: 152
References: 94
Citations by year: 2026: 4 · 2025: 12 · 2024: 13 · 2023: 14 · 2022: 19 · 2021: 19 · 2020: 18 · 2019: 10 · 2018: 12 · 2017: 16 · 2016: 13 · 2015: 2
FWCI: 12.40
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Cardiovascular Drugs and Therapy (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Sex and Gender in Healthcare
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
Keywords: metabolic syndrome, sex differences, gender differences, cardiovascular disease, type 2 diabetes, atherosclerotic cardiovascular disease, obesity, pathophysiology
MeSH terms: Animals, Female, Hormones, Humans, Male, Polycystic Ovary Syndrome, Sex Characteristics, Metabolic Syndrome

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Metabolic Syndrome: Does it Differ Between Women and Men?

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