A Head-to-Head Comparison of Aripiprazole and Risperidone for Safety and Treating Autistic Disorders, a Randomized Double Blind Clinical Trial
Open accessAbstract
Aripiprazole and risperidone are the only FDA approved medications for treating irritability in autistic disorder, however there are no head-to-head data comparing these agents. This is the first prospective randomized clinical trial comparing the safety and efficacy of these two medications in patients with autism spectrum disorders. Fifty nine children and adolescents with autism spectrum disorders were randomized to receive either aripiprazole or risperidone for 2 months. The primary outcome measure was change in Aberrant Behavior Checklist (ABC) scores. Adverse events were assessed. Aripiprazole as well as risperidone lowered ABC scores during 2 months. The rates of adverse effects were not significantly different between the two groups. The safety and efficacy of aripiprazole (mean dose 5.5 mg/day) and risperidone (mean dose 1.12 mg/day) were comparable. The choice between these two medications should be on the basis of clinical equipoise considering the patient's preference and clinical profile.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Risperidone and aripiprazole have shown similar efficacy and safety profiles in comparison clinical trials.
“Risperidone and aripiprazole have shown similar efficacy and safety profiles in comparison clinical trials [136, 137]”
From Pharmacological treatment in autism: a proposal for guidelines on common co-occurring psychiatric symptoms (2025) · cites this paper as [136]
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,841 · see citing works
Diagnostic and Statistical Manual of Mental Disorders.
Widiger, T. A. (2000) · Oxford University Press eBooks · doi:10.1037/10518-009 · Cited by 19,767 · see citing works
Lord, C., Rutter, M., & Le Couteur, A. (1994) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02172145 · Cited by 9,065 · see citing works
Global Prevalence of Autism and Other Pervasive Developmental Disorders
Elsabbagh, M., Divan, G., Koh, Y., Kim, Y. S., Kauchali, S., Marcín, C., Montiel‐Nava, C., Patel, V., Paula, C. S., Wang, C., et al. (2012) · Autism Research · doi:10.1002/aur.239 · Cited by 2,636 · see citing works
(1985) · PubMed · Cited by 1,427 · see citing works
The American Psychiatric Association at Washington
(1930) · Psychiatric Quarterly · doi:10.1007/bf01579058 · Cited by 771 · see citing works
A Systematic Review of Medical Treatments for Children With Autism Spectrum Disorders
McPheeters, M. L., Warren, Z., Sathe, N., Bruzek, J. L., Krishnaswami, S., Jerome, R. N., & Veenstra-VanderWeele, J. (2011) · Pediatrics · doi:10.1542/peds.2011-0427 · Cited by 356 · see citing works
Maayan, L. A., & Correll, C. U. (2011) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2011.0015 · Cited by 253 · see citing works
Risperidone for autism spectrum disorder
Jesner, O., Aref‐Adib, M., & Coren, E. (2007) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005040.pub2 · Cited by 193 · see citing works
Acute and Long-Term Safety and Tolerability of Risperidone in Children with Autism
Aman, M. G., Arnold, L. E., McDougle, C. J., Vitiello, B., Scahill, L. D., Davies, M., McCracken, J. T., Tierney, E., Nash, P. L., Posey, D. J., et al. (2005) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2005.15.869 · Cited by 170 · see citing works
Asadabadi, M., Mohammadi, M.-R., Ghanizadeh, A. J., Modabbernia, A., Ashrafi, M., Hassanzadeh, E., Forghani, S., & Akhondzadeh, S. (2012) · Psychopharmacology · doi:10.1007/s00213-012-2796-8 · Cited by 143 · see citing works
Self-citationGlutathione-Related Factors and Oxidative Stress in Autism, A Review
Ghanizadeh, A. J., Akhondzadeh, S., Hormozi, M., Makarem, A., Zarchi, M. A., & Firoozabadi, A. (2012) · Current Medicinal Chemistry · doi:10.2174/092986712802002572 · Cited by 134 · see citing works
Self-citationRezaei, V., Mohammadi, M.-R., Ghanizadeh, A. J., Sahraian, A., Tabrizi, M. H., Rezazadeh, S., & Akhondzadeh, S. (2010) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.07.005 · Cited by 124 · see citing works
Self-citationAkhondzadeh, S., Fallah, J., Mohammadi, M.-R., Imani, R., Mohammadi, M., Salehi, B., Ghanizadeh, A. J., Raznahan, M., Mohebbi-Rasa, S., Rezazadeh, S., et al. (2009) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2009.09.012 · Cited by 112 · see citing works
Self-citationMarcus, R. N., Owen, R., Manos, G., Mankoski, R., Kamen, L., McQuade, R. D., Carson, W. H., Corey-Lisle, P. K., & Aman, M. G. (2011) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2009.0121 · Cited by 82 · see citing works
Hasanzadeh, E., Mohammadi, M.-R., Ghanizadeh, A. J., Rezazadeh, S., Tabrizi, M. H., Rezaei, F., & Akhondzadeh, S. (2012) · Child Psychiatry & Human Development · doi:10.1007/s10578-012-0292-3 · Cited by 66 · see citing works
Self-citationVarni, J. W., Handen, B. L., Corey‐Lisle, P. K., Guo, Z., Manos, G., Ammerman, D. K., Marcus, R. N., Owen, R., McQuade, R. D., Carson, W. H., et al. (2012) · Clinical Therapeutics · doi:10.1016/j.clinthera.2012.02.023 · Cited by 60 · see citing works
Scott, L. J., & Dhillon, S. (2007) · Pediatric Drugs · doi:10.2165/00148581-200709050-00006 · Cited by 59 · see citing works
Aripiprazole for the treatment of irritability associated with autism
Farmer, C., & Aman, M. G. (2011) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2011.557661 · Cited by 46 · see citing works
McKinney, C., & Renk, K. (2010) · Clinical Psychology Review · doi:10.1016/j.cpr.2010.11.005 · Cited by 44 · see citing works
Atomoxetine for Treating ADHD Symptoms in Autism: A Systematic Review
Ghanizadeh, A. (2013) · Journal of Attention Disorders · doi:10.1177/1087054712443154 · Cited by 43 · see citing works
Self-citationGhanizadeh, A. J., Berk, M., Farrashbandi, H., Shoushtari, A. A., & Villagonzalo, K.-A. (2012) · Mitochondrion · doi:10.1016/j.mito.2012.10.001 · Cited by 37 · see citing works
Self-citationRobb, A. S., Andersson, C., Bellocchio, E. E., Manos, G., Rojas‐Fernandez, C. H., Mathew, S., Marcus, R. N., Owen, R., & Mankoski, R. E. (2011) · The Primary Care Companion For CNS Disorders · doi:10.4088/pcc.10m01008gry · Cited by 35 · see citing works
Ghanizadeh, A. J. (2012) · Medical Gas Research · doi:10.1186/2045-9912-2-13 · Cited by 26 · see citing works
Self-citationEstimated prevalence of autism spectrum conditions in Cambridgeshire is over 1%
Fombonne, E. J. (2010) · Evidence-Based Mental Health · doi:10.1136/ebmh.13.1.32 · Cited by 20 · see citing works
Curran, M. P. (2011) · Pediatric Drugs · doi:10.2165/11207230-000000000-00000 · Cited by 17 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
An update on pharmacotherapy for autism spectrum disorder in children and adolescents
Ji, N. Y., & Findling, R. L. (2015) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000132 · Cited by 217 · see citing works
Aripiprazole for autism spectrum disorders (ASD)
Hirsch, L., & Pringsheim, T. M. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009043.pub3 · Cited by 203 · see citing works
An update on pharmacotherapy of autism spectrum disorder in children and adolescents
Goel, R., Hong, J. S., Findling, R. L., & Ji, N. Y. (2018) · International Review of Psychiatry · doi:10.1080/09540261.2018.1458706 · Cited by 191 · see citing works
Treatment of Autism Spectrum Disorder in Children and Adolescents
DeFilippis, M., & Wagner, K. D. (2025) · Psychopharmacology Bulletin · doi:10.64719/pb.4346 · Cited by 178 · see citing works
Lee, R. W. Y., Corley, M. J., Pang, A. P. S., Arakaki, G., Abbott, L., Nishimoto, M., Miyamoto, R. H., Lee, E., Yamamoto, S., Maunakea, A. K., et al. (2018) · Physiology & Behavior · doi:10.1016/j.physbeh.2018.02.006 · Cited by 165 · see citing works
Ghanizadeh, A. J., & Sarani, E. M. (2013) · BMC Psychiatry · doi:10.1186/1471-244x-13-196 · Cited by 158 · see citing works
Self-citationPersico, A. M., Ricciardello, A., Lamberti, M., Turriziani, L., Cucinotta, F., Brogna, C., Vitiello, B., & Arango, C. (2021) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2021.110326 · Cited by 138 · see citing works
Psychopharmacological interventions in autism spectrum disorder
Accordino, R. E., Kidd, C. L., Politte, L. C., Henry, C. A., & McDougle, C. J. (2016) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2016.1154536 · Cited by 128 · see citing works
Fallah, M. S., Shaikh, M. R., Neupane, B., Rusiecki, D. R., Bennett, T. A., & Beyene, J. (2019) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2018.0115 · Cited by 116 · see citing works
Ichikawa, H., Mikami, K., Okada, T., Yamashita, Y., Ishizaki, Y., Tomoda, A., Ono, H., Usuki, C., & Tadori, Y. (2016) · Child Psychiatry & Human Development · doi:10.1007/s10578-016-0704-x · Cited by 108 · see citing works
Rodrigues, R., Lai, M., Beswick, A., Gorman, D. A., Anagnostou, E., Szatmari, P., Anderson, K. K., & Ameis, S. H. (2021) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.13305 · Cited by 98 · see citing works
Obesity Prevention for Children with Developmental Disabilities
Must, A., Curtin, C., Hubbard, K. L., Sikich, L., Bedford, J., & Bandini, L. G. (2014) · Current Obesity Reports · doi:10.1007/s13679-014-0098-7 · Cited by 96 · see citing works
McQuire, C., Hassiotis, A., Harrison, B. A., & Pilling, S. (2015) · BMC Psychiatry · doi:10.1186/s12888-015-0688-2 · Cited by 91 · see citing works
de Pablo, G. S., Jordá, C. P., Vaquerizo‐Serrano, J., Moreno, C., Cabras, A., Arango, C., Hernandez, P. A., Veenstra-VanderWeele, J. M., Simonoff, E. A., Fusar‐Poli, P., et al. (2022) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2022.03.033 · Cited by 92 · see citing works
Im, D. S. (2016) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000087 · Cited by 81 · see citing works
Rossignol, D. A., & Frye, R. E. (2014) · Frontiers in Pediatrics · doi:10.3389/fped.2014.00087 · Cited by 79 · see citing works
Approaches to Understanding Multisensory Dysfunction in Autism Spectrum Disorder
Siemann, J. K., Veenstra‐VanderWeele, J., & Wallace, M. T. (2020) · Autism Research · doi:10.1002/aur.2375 · Cited by 74 · see citing works
Risperidone for children and adolescents with autism spectrum disorder: a systematic review
Maneeton, N., Maneeton, B., Putthisri, S., Woottiluk, P., Narkpongphun, A., & Srisurapanont, M. (2018) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s151802 · Cited by 73 · see citing works
Cheng, Y., Tseng, P., Chen, Y., Stubbs, B., Yang, W.-C., Chen, T., Wu, C.-K., & Lin, P. (2017) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s147305 · Cited by 68 · see citing works
Stepanova, E. A., Dowling, S., Phelps, M., & Findling, R. L. (2017) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2017.19.4/rfindling · Cited by 61 · see citing works
DeVane, C. L., Charles, J. M., Abramson, R. K., Williams, J. E., Carpenter, L. A., Raven, S., Gwynette, F., Stuck, C. A., Geesey, M. E., Bradley, C., et al. (2019) · Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy · doi:10.1002/phar.2271 · Cited by 60 · see citing works
Effects of Risperidone in Autistic Children and Young Adults: A Systematic Review and Meta-Analysis
Mano‐Sousa, B. J., Pedrosa, A. M., Alves, B. C., Galduróz, J. C. F., Belo, V. S., Chaves, V. E., & Duarte‐Almeida, J. M. (2020) · Current Neuropharmacology · doi:10.2174/1570159x18666200529151741 · Cited by 62 · see citing works
Ghanizadeh, A. J., & Haghighi, A. (2013) · Child Psychiatry & Human Development · doi:10.1007/s10578-013-0427-1 · Cited by 59 · see citing works
Self-citationAlfageh, B. H., Wang, Z., Mongkhon, P., Besag, F., Alhawassi, T. M., Brauer, R., & Wong, I. C. K. (2019) · Pediatric Drugs · doi:10.1007/s40272-019-00333-x · Cited by 58 · see citing works
Ghanizadeh, A. J., & Ayoobzadehshirazi, A. (2014) · Pediatric Neurology · doi:10.1016/j.pediatrneurol.2014.09.017 · Cited by 56 · see citing works
Self-citationOn Behalf of the ISACA Guideline Working Group, D’Alò, G. L., De Crescenzo, F., Amato, L., Cruciani, F., Davoli, M., Fulceri, F., Minozzi, S., Mitrova, Z., Morgano, G. P., et al. (2021) · Health and Quality of Life Outcomes · doi:10.1186/s12955-021-01669-0 · Cited by 54 · see citing works
The psychopharmacology of autism spectrum disorder and Rett syndrome
Persico, A. M., Ricciardello, A., & Cucinotta, F. (2019) · Handbook of clinical neurology · doi:10.1016/b978-0-444-64012-3.00024-1 · Cited by 53 · see citing works
An Update on Medication Management of Behavioral Disorders in Autism
Baribeau, D. A., & Anagnostou, E. A. (2014) · Current Psychiatry Reports · doi:10.1007/s11920-014-0437-0 · Cited by 51 · see citing works
Okubo, R., Hasegawa, T., Fukuyama, K., Shiroyama, T., & Okada, M. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.623684 · Cited by 51 · see citing works
Wetie, A. G. N., Wormwood, K. L., Charette, L., Ryan, J. P., Woods, A. G., & Darie, C. C. (2015) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.12658 · Cited by 49 · see citing works
Iffland, M., Livingstone, N., Jorgensen, M. L., Hazell, P., & Gillies, D. M. (2023) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011769.pub2 · Cited by 55 · see citing works
Aripiprazole in Children and Adolescents
Coustals, N., Ménard, M.-L., & Cohen, D. (2020) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2020.0014 · Cited by 45 · see citing works
Manter, M. A., Birtwell, K. B., Bath, J., Friedman, N. D. B., Keary, C. J., Neumeyer, A. M., Palumbo, M. L., Thom, R. P., Stonestreet, E., Brooks, H., et al. (2025) · BMC Medicine · doi:10.1186/s12916-024-03814-0 · Cited by 51 · see citing works
“Risperidone and aripiprazole have shown similar efficacy and safety profiles in comparison clinical trials [136, 137], though one meta-analysis on pharmacological treat-ment of irritability and problem behaviors in ASD did report that the number of subjects needed to treat was lower for risperidone…”
Harms of Antipsychotics in Children and Young Adults: A Systematic Review Update
Pillay, J., Boylan, K., Newton, A. S., Hartling, L., Vandermeer, B., Nuspl, M., MacGregor, T., Featherstone, R. M., & CARREY, N. J. (2018) · The Canadian Journal of Psychiatry · doi:10.1177/0706743718779950 · Cited by 43 · see citing works
Hesapçıoğlu, S. T., Ceylan, M. F., Kaşak, M., & Şen, C. P. (2020) · Research in Autism · doi:10.1016/j.rasd.2020.101520 · Cited by 41 · see citing works
Effects of 5-HT-7 receptor ligands on memory and cognition
Zareifopoulos, N., & Papatheodoropoulos, C. (2016) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2016.10.011 · Cited by 40 · see citing works
Maneeton, N., Maneeton, B., Putthisri, S., Suttajit, S., Likhitsathian, S., & Srisurapanont, M. (2018) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s174622 · Cited by 38 · see citing works
Aripiprazole for treating irritability associated with autism spectrum disorders
Bartram, L. R., Lozano, J., & Coury, D. L. (2019) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2019.1626825 · Cited by 40 · see citing works
Panda, P. K., Sharawat, I. K., Saha, S., Gupta, D., Palayullakandi, A., & Meena, K. (2024) · European Journal of Pediatrics · doi:10.1007/s00431-024-05762-6 · Cited by 37 · see citing works
RetractedThe promising trajectory of autism therapeutics discovery
Silverman, J. L., & Crawley, J. N. (2013) · Drug Discovery Today · doi:10.1016/j.drudis.2013.12.007 · Cited by 34 · see citing works
Rahi, S., & Mehan, S. (2020) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-020-01010-1 · Cited by 36 · see citing works
Therapeutic Potential and Limitation of Serotonin Type 7 Receptor Modulation
Fukuyama, K., Motomura, E., & Okada, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032070 · Cited by 33 · see citing works
Is Oxytocin Application for Autism Spectrum Disorder Evidence-Based?
Lee, S. Y., Lee, A. R., Hwangbo, R., Han, J., Hong, M., & Bahn, G. H. (2015) · Experimental Neurobiology · doi:10.5607/en.2015.24.4.312 · Cited by 32 · see citing works
Singla, R., Mishra, A., & Cao, R. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-02120-8 · Cited by 33 · see citing works
Safety and tolerability of antipsychotic agents in neurodevelopmental disorders: a systematic review
Iasevoli, F., Barone, A., Buonaguro, E. F., Vellucci, L., & de Bartolomeis, A. (2020) · Expert Opinion on Drug Safety · doi:10.1080/14740338.2020.1820985 · Cited by 30 · see citing works
Serotonergic neuromodulation of synaptic plasticity
Higa, G. S. V., Viana, F. J. C., Francis-Oliveira, J., Cruvinel, E., Franchin, T. S., Marcourakis, T., Ulrich, H., & De Pasquale, R. (2024) · Neuropharmacology · doi:10.1016/j.neuropharm.2024.110036 · Cited by 29 · see citing works
Masi, A., Lampit, A., DeMayo, M. M., Glozier, N., Hickie, I. B., & Guastella, A. J. (2017) · Psychological Medicine · doi:10.1017/s0033291716003457 · Cited by 29 · see citing works
Popow, C., Ohmann, S., & Plener, P. L. (2021) · Neuropsychiatrie · doi:10.1007/s40211-021-00395-9 · Cited by 36 · see citing works
Koevoet, D., Deschamps, P. K. H., & Kenemans, J. L. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.1078586 · Cited by 28 · see citing works
Iwashita, M., & Yoshizawa, M. (2021) · eLife · doi:10.7554/elife.72463 · Cited by 18 · see citing works
Pavăl, D., Rad, F., Rusu, R., Niculae, A.-Ş., Colosi, H. A., Dobrescu, I., & Dronca, E. (2017) · Clinical Psychopharmacology and Neuroscience · doi:10.9758/cpn.2017.15.3.229 · Cited by 22 · see citing works
Drug treatment of autism spectrum disorder and its comorbidities in children and adolescents
Santosh, P., & Singh, J. (2016) · BJPsych Advances · doi:10.1192/apt.bp.115.014597 · Cited by 21 · see citing works
Dinnissen, M., Dietrich, A., van den Hoofdakker, B. J., & Hoekstra, P. J. (2014) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1517/17425255.2015.981151 · Cited by 21 · see citing works
Atypical antipsychotics for autism spectrum disorder: a network meta-analysis
Meza, N., Franco, J. V. A., Sguassero, Y., Núñez, V., Liquitay, C. M. E., Rees, R., Williams, K. J., Rojas, V., Rojas, F., Pringsheim, T. M., et al. (2025) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd014965.pub2 · Cited by 23 · see citing works
Montagner, P. S. S., Medeiros, W., da Silva, L. C. R., Borges, C. N., Brasil-Neto, J. P., Barbosa, V. D. D. S., Caixeta, F. V., & Malcher‐Lopes, R. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1210155 · Cited by 20 · see citing works
Alrehaili, R. A., Elkady, R. M., Alrehaili, J. A., & Alreefi, R. (2023) · Cureus · doi:10.7759/cureus.50111 · Cited by 22 · see citing works
Rizzo, R., & Pavone, P. (2016) · Expert Review of Neurotherapeutics · doi:10.1080/14737175.2016.1211007 · Cited by 19 · see citing works
Akhtar, A., & Rahaman, S. B. (2025) · Brain Sciences · doi:10.3390/brainsci15080853 · Cited by 21 · see citing works
Krill, R. A., & Kumra, S. (2014) · Adolescent Health, Medicine and Therapeutics · doi:10.2147/ahmt.s49807 · Cited by 20 · see citing works
Brexpiprazole Reduces 5-HT7 Receptor Function on Astroglial Transmission Systems
Fukuyama, K., Motomura, E., & Okada, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23126571 · Cited by 16 · see citing works
Aripiprazole for treating irritability in children & adolescents with autism: A systematic review
Ghanizadeh, A. J., Tordjman, S., & Jaafari, N. (2015) · The Indian Journal of Medical Research · doi:10.4103/0971-5916.166584 · Cited by 16 · see citing works
Self-citationAvailable Treatments for Autism Spectrum Disorder: From Old Strategies to New Options
Dell’Osso, L., Bonelli, C., Giovannoni, F., Poli, F., Anastasio, L., Cerofolini, G., Nardi, B., Cremone, I. M., Pini, S., & Carpita, B. (2025) · Pharmaceuticals · doi:10.3390/ph18030324 · Cited by 15 · see citing works
Faja, S., Sabatos‐DeVito, M., Sridhar, A., Kuhn, J., Nikolaeva, J. I., Sugar, C. A., Webb, S. J., Bernier, R., Sikich, L., Hellemann, G., et al. (2023) · Autism Research · doi:10.1002/aur.2905 · Cited by 14 · see citing works
KANPHOS: A Database of Kinase-Associated Neural Protein Phosphorylation in the Brain
Ahammad, R. U., Nishioka, T., Yoshimoto, J., Kannon, T., Amano, M., Funahashi, Y., Tsuboi, D., Faruk, M. O., Yamahashi, Y., Yamada, K., et al. (2021) · Cells · doi:10.3390/cells11010047 · Cited by 13 · see citing works
The effect of stimulants on irritability in autism comorbid with ADHD: a systematic review
Ghanizadeh, A. J., Molla, M., & Olango, G. (2019) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s194022 · Cited by 12 · see citing works
Self-citationMyers, S. M., & Challman, T. D. (2018) · American Academy of PediatricsItasca, IL eBooks · doi:10.1542/9781610021357-19 · Cited by 12 · see citing works
Assessing and treating aggression in children and adolescents
Adesanya, D. O., Johnson, J. L., & Galanter, C. A. (2021) · Pediatric Medicine · doi:10.21037/pm-20-109 · Cited by 13 · see citing works
Kim, H., Park, E. J., Kim, J.-H., Boon‐yasidhi, V., Tarugsa, J., Reyes, A., Manalo, S. G., & Joung, Y. (2018) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2017.0152 · Cited by 11 · see citing works
Carthy, E. R., Ross, C. C., & Murphy, D. (2021) · BJPsych Advances · doi:10.1192/bja.2021.32 · Cited by 10 · see citing works
Ghanizadeh, A. J. (2013) · Neurosciences · doi:10.17712/1658-3183.2036 · Cited by 10 · see citing works
Self-citationAtypical antipsychotics for autism spectrum disorder: a network meta-analysis
Meza, N., Rees, R., Liquitay, C. M. E., Franco, J. V. A., Sguassero, Y., Williams, K. J., Pringsheim, T. M., Rojas, V., & Eva Madrid, A. (2022) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd014965 · Cited by 10 · see citing works
Panda, P. K., Sharawat, I. K., Gupta, D., Palayullakandi, A., Sopanam, S., & Saha, S. (2025) · Brain and Development · doi:10.1016/j.braindev.2025.104454 · Cited by 10 · see citing works
Yerokhin, V., Carr, B., Sneed, G., & Vassar, M. B. (2016) · BMC Research Notes · doi:10.1186/s13104-016-2280-3 · Cited by 9 · see citing works
Fukuyama, K., Motomura, E., & Okada, M. (2023) · Biomolecules · doi:10.3390/biom13091288 · Cited by 8 · see citing works
Psychopharmacology of Neurodevelopmental Disorders in Children
Singh, J., & Santosh, P. (2016) · Springer eBooks · doi:10.1007/978-81-322-3619-1_18 · Cited by 8 · see citing works
Psychiatric Diseases in Children and Adolescents
Cardwell, G. S., Findling, R. L., & Robb, A. S. (2019) · Handbook of experimental pharmacology · doi:10.1007/164_2019_262 · Cited by 7 · see citing works
Baumer, N., & Capone, G. T. (2023) · American Journal of Medical Genetics Part C Seminars in Medical Genetics · doi:10.1002/ajmg.c.32069 · Cited by 6 · see citing works
Shilbayeh, S. A. R., Adeen, I. S., Alhazmi, A. S., Aljurayb, H., Altokhais, R. S., Alhowaish, N., Aldilaijan, K. E., Kamal, M., & Alnakhli, A. M. (2024) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-024-03658-w · Cited by 5 · see citing works
Bahji, A., Forth, E., Nasar, A., Waqas, A., Hawken, E. R., & Ayub, M. (2024) · Journal of Psychopharmacology · doi:10.1177/02698811241303654 · Cited by 5 · see citing works
Alfageh, B. H., Besag, F., Gao, L., Ma, T., Man, K. K. C., Wong, I. C. K., & Brauer, R. (2021) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-021-05208-0 · Cited by 5 · see citing works
Psychopharmacology of Autism Spectrum Disorder
Calles, J. L. (2019) · Psychiatric Annals · doi:10.3928/00485713-20190206-01 · Cited by 5 · see citing works
Pediatric Pharmacologic Management of Autism-Associated Behavioral Dysregulation
Xiong, W. (2017) · American Journal of Psychiatry Residents Journal · doi:10.1176/appi.ajp-rj.2017.120902 · Cited by 4 · see citing works
Using Aripiprazole to Benefit People with Autism Spectrum Disorder: a Critical Appraisal
VanDerwall, R., Rotta, K., Ehrhardt, K. E., & Poling, A. D. (2021) · Advances in Neurodevelopmental Disorders · doi:10.1007/s41252-020-00190-7 · Cited by 4 · see citing works
Neurodevelopmental and Neuropsychiatric Disorders
Monji, A., Maezawa, I., Mizoguchi, Y., Kato, T. A., & Jin, L. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1429-6_14 · Cited by 4 · see citing works
Cazares, C., Hutton, A., Paez, G., Trauner, D. A., & Voytek, B. (2026) · Translational Psychiatry · doi:10.1038/s41398-026-03815-y · Cited by 4 · see citing works
SEGURANÇA DA RISPERIDONA EM CRIANÇAS E ADOLESCENTES COM TRANSTORNO DO ESPECTRO AUTISTA
Neves, K. R. T., Albuquerque, I. M., Xavier, E. L. P., Martins, S. D. O., & Aragão, G. F. (2021) · Infarma - Ciências Farmacêuticas · doi:10.14450/2318-9312.v33.e2.a2021.pp138-148 · Cited by 2 · see citing works
Shaw, S. R., & Wang, J. (2022) · Autism and child psychopathology series · doi:10.1007/978-3-030-88538-0_52 · Cited by 3 · see citing works
da Silva, J. F., Honorato, M. M., Cremaschi, R. C., & Coelho, F. M. S. (2023) · Journal of Neurosciences in Rural Practice · doi:10.25259/jnrp_53_2022 · Cited by 3 · see citing works
(2021) · Wiley eBooks · doi:10.1002/9781119870203.mpg005 · Cited by 3 · see citing works
Integrating Treatment for Autism: Psychiatric Comorbidities and Comprehensive Treatment
Parenteau, C. I., Tsipan, R. M., & Hendren, R. L. (2021) · Autism and Developmental Disorders · doi:10.17759/autdd.2021190105 · Cited by 2 · see citing works
Pharmacological approaches in the treatment of autism: a narrative review
Medeiros, G. M., Sepulveda, M. M., Gentile, J. K. D. A., & Braga, A. L. F. (2022) · Brazilian Journal of Case Reports · doi:10.52600/2763-583x.bjcr.2022.2.4.3-32 · Cited by 2 · see citing works
The use of aripiprazole in the treatment of mental disorders in children and adolescents
Cichoń, L., Gabryel, B., Jelonek, I., Krysta, K., & Janas-Kozik, M. H. (2018) · Psychiatria i Psychologia Kliniczna · doi:10.15557/pipk.2018.0045 · Cited by 2 · see citing works
Psychopharmacology of Autism Spectrum Disorders
Mooney, L. N., Fosdick, C., & Erickson, C. A. (2019) · Cambridge University Press eBooks · doi:10.1017/9781108297769.008 · Cited by 2 · see citing works
Sappok, T., Sinzig, J., Lehmkuhl, G., & Diefenbacher, A. (2019) · Elsevier eBooks · doi:10.1016/b978-3-437-22485-0.00024-5 · Cited by 2 · see citing works
Мартыненко, А. И., Емельянцева, Т. А., & Захаревич, О. Ю. (2021) · Психиатрия психотерапия и клиническая психология · doi:10.34883/pi.2020.11.4.010 · Cited by 2 · see citing works
Chapter 60. Treatment of Child and Adolescent Disorders
Wagner, K., & Pliszka, S. R. (2024) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615375523.as60 · Cited by 1 · see citing works
Tai, L., & Cui, Y. (2026) · International Journal of Developmental Disabilities · doi:10.1080/20473869.2026.2628973 · Cited by 1 · see citing works
Orlik, H., & Halawa, N. (2016) · Child and Adolescent Psychopharmacology News · doi:10.1521/capn.2016.21.3.1 · Cited by 1 · see citing works
Pharmacotherapies for Children with Autism Spectrum Disorder
Cardwell, G. S. (2017) · Child and Adolescent Psychopharmacology News · doi:10.1521/capn.2017.22.6.1 · Cited by 1 · see citing works
- Authors
- Ghanizadeh, A., Sahraeizadeh, A., & Berk, M.
- Affiliations
- Shiraz University (IR)
- Deakin University (AU)
- Corresponding author
- Ghanizadeh, Ahmad
- Venue
- Child Psychiatry & Human Development
- Published
- 2013-06-26
- Volume
- 45
- Issue
- 2
- Pages
- 185-192
- ISSN
- 0009-398X (ISSN-L)
- 1573-3327
- OpenAlex
- W1969516074
- Cited by
- 134
- References
- 26
- Citations by year
- 2026: 9 · 2025: 7 · 2024: 5 · 2023: 9 · 2022: 7 · 2021: 25 · 2020: 12 · 2019: 12 · 2018: 11 · 2017: 7 · 2016: 11 · 2015: 7 · 2014: 8 · 2013: 4
- FWCI
- 5.47
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Child Psychiatry & Human Development (publishedVersion)
- PubMed (publishedVersion)
- Minerva Access (University of Melbourne) (submittedVersion)
- Deakin Research Online (Deakin University) (submittedVersion)
- Funders
- Bristol-Myers Squibb
- Eli Lilly and Company
- Pfizer
- Sanofi
- Geelong Region Medical Research Foundation
- Beyond Blue
- Shiraz University of Medical Sciences
- Shiraz University
- Servier
- H. Lundbeck A/S
- National Institutes of Health
- National Health and Medical Research Council
- Cilag
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Keywords
- aripiprazole, risperidone, autism spectrum disorder, irritability, antipsychotic drugs, Aberrant Behavior Checklist, adverse events, drug safety, children and adolescents, clinical equipoise
- MeSH terms
- Aripiprazole, Adolescent, Autistic Disorder, Body Weight, Child, Child, Preschool, Dose-Response Relationship, Drug, Double-Blind Method, Female, Humans, Irritable Mood, Male, Piperazines, Antipsychotic Agents, Quinolones, Treatment Outcome, Risperidone
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
