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From methotrexate to pemetrexed and beyond. A review of the pharmacodynamic and clinical properties of antifolates

Walling, Jackie·2006·Investigational New Drugs

DOI 10.1007/s10637-005-4541-1

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Authors: Walling, J.
Affiliations: University of Bristol (GB)
Corresponding author: Walling, Jackie
ORCID: Walling, Jackie
Venue: Investigational New Drugs
Publisher: Springer Science and Business Media LLC
Published: 2006-01
Volume: 24
Issue: 1
Pages: 37-77
ISSN: 0167-6997 (ISSN-L)
1573-0646
DOI: 10.1007/s10637-005-4541-1
OpenAlex: W1993777583
Cited by: 182
References: 353
Citations by year: 2026: 4 · 2025: 7 · 2024: 9 · 2023: 4 · 2022: 11 · 2021: 15 · 2020: 12 · 2019: 10 · 2018: 7 · 2017: 7 · 2016: 8 · 2015: 17 · 2014: 9 · 2013: 7 · 2012: 8
FWCI: 1.55
Type: journal article
Language: en
Open access: closed
Licence: www.springernature.com/gp/researchers/text-and-data-mining (tdm)
www.springernature.com/gp/researchers/text-and-data-mining (vor)
Locations: Investigational New Drugs (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Nursing › Nutrition and Dietetics › Folate and B Vitamins Research
Health Sciences › Medicine › Oncology › Colorectal Cancer Treatments and Studies
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Cancer therapeutics and mechanisms
Keywords: antifolate, methotrexate, pemetrexed, pharmacodynamics, clinical properties
MeSH terms: Pemetrexed, Antineoplastic Agents, Antineoplastic Combined Chemotherapy Protocols, Biological Transport, Folic Acid Antagonists, Glutamates, Guanine, Humans, Methotrexate, Neoplasms, Randomized Controlled Trials as Topic, Clinical Trials, Phase II as Topic, Clinical Trials, Phase III as Topic, Drug Resistance, Neoplasm

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From methotrexate to pemetrexed and beyond. A review of the pharmacodynamic and clinical properties of antifolates

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