The Relationship Between Emotion Dysregulation and Error Monitoring in Adolescents with ADHD
Open accessAbstract
Attention-deficit/hyperactivity disorder (ADHD) is emblematic of the limitations of existing diagnostic categories. One potential solution, consistent with the Research Domain Criteria (RDoC) initiative, is to interrogate psychological mechanisms at the behavioral and physiological level together to try and identify meaningful subgroups within existing categories. Such approaches provide a way to revise diagnostic boundaries and clarify individual variation in mechanisms. Here, we illustrate this approach to help resolve heterogeneity in ADHD using a combination of behaviorally-rated temperament measures from the Early Adolescent Temperament Questionnaire; cognitive performance on three difference conditions of an emotional go/no-go task; and electroencephalogram (EEG)-measured variation in multiple stages of error processing, including the error-related negativity (ERN) and positivity (Pe). In a large (N = 342), well-characterized sample of adolescents with ADHD, latent profile analysis identified two ADHD temperament subgroups: 1) emotionally regulated and 2) emotionally dysregulated (with high negative affect). Cognitive and EEG assessment in a subset of 272 adolescents (nADHD = 151) found that the emotionally dysregulated group showed distinct patterns of change in early neural response to errors (ERN) across emotional task conditions as compared to emotionally-regulated ADHD adolescents and typically-developing controls. Both ADHD groups showed blunted later response to errors (Pe) that was stable across emotional task conditions. Overall, neural response patterns identified important differences in how trait and state emotion interact to affect cognitive processing. Results highlight important temperament variation within ADHD that helps clarify its relationship to the ERN, one of the most prominent putative neural biomarkers for psychopathology.
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Reduced ERN and Pe amplitudes have been found in studies of children and adults with ADHD using choice reaction time tasks.
“Reduced ERN and Pe amplitudes have been found in studies of children and adults with ADHD using choice reaction time tasks, suggesting the ERN and Pe may serve as biomarkers for the disorder (Bellato et al. 2021; Figuracion et al. 2024; Geburek et al. 2013; Kaiser et al. 2020; Liu et al. 2020; Lutz et al. 2021).”
From Reaction Time Variability and Electrophysiological Indices of Performance Monitoring in Youths With Attention-Deficit/Hyperactivity Disorder and Obsessive-Compulsive Disorder (2026) · cites this paper as Figuracion et al. 2024
The Results (ADHD Diagnostic Group Comparisons; page unavailable) report reduced Pe in adolescents with ADHD, but no overall ERN difference; the Discussion reports reduced ERN only in particular temperament groups and task conditions. The Methods (Measures; page unavailable) describe a go/no-go task, not a choice reaction time task, and this study did not include adults. (LLM, conf=0.90)
Experimental — accuracy not yet measuredADHD and OCD may be differentiated by neurocognitive measures and neural indices of error monitoring.
“ADHD and OCD are common psychiatric disorders that may be differentiated by neurocognitive measures and neural indices of error monitoring (Figuracion et al. 2024; Hanna et al. 2026; Kaiser et al. 2020; Kofler et al. 2013; Lamothe et al. 2025; Liu et al. 2020; Lutz et al. 2021; Tamm et al. 2012).”
From Reaction Time Variability and Electrophysiological Indices of Performance Monitoring in Youths With Attention-Deficit/Hyperactivity Disorder and Obsessive-Compulsive Disorder (2026) · cites this paper as Figuracion et al. 2024
The Abstract (page unavailable) reports that cognitive-task performance and EEG indices of error monitoring distinguished subgroups of adolescents with ADHD and compared them with typically developing controls. The Discussion (page unavailable) likewise addresses differences within ADHD. The paper does not show that these measures differentiate ADHD from OCD. (LLM, conf=0.86)
Experimental — accuracy not yet measuredThe Pe results are consistent with a meta-analysis that concluded a reduced Pe is associated more reliably with ADHD than a reduced ERN.
“Our Pe results are consistent with a meta‐analysis that concluded a reduced Pe is associated more reliably with ADHD than a reduced ERN (Kaiser et al. 2020) and with the recent finding of a blunted Pe in a large study of adolescents with ADHD (Figuracion et al. 2024).”
From Reaction Time Variability and Electrophysiological Indices of Performance Monitoring in Youths With Attention-Deficit/Hyperactivity Disorder and Obsessive-Compulsive Disorder (2026) · cites this paper as Figuracion et al. 2024
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Sorted by citations
Hanna, G. L., Liu, Y., Hanna, B. S., Arnold, P. D., & Gehring, W. J. (2026) · Psychophysiology · doi:10.1111/psyp.70403
- Authors
- Figuracion, M. T., Kozlowski, M. B., Macknyk, K. S., Heise, M. B., Pieper, S. M., Alperin, B. R., Morton, H. E., Nigg, J. T., & Karalunas, S. L.
- Affiliations
- Purdue University West Lafayette (US)
- Oregon Health & Science University (US)
- Corresponding author
- Figuracion, McKenzie T.
- ORCID
- Venue
- Research on Child and Adolescent Psychopathology
- Published
- 2023-10-16
- Volume
- 52
- Issue
- 4
- Pages
- 605-620
- ISSN
- 0091-0627 (ISSN-L)
- 2730-7166
- 2730-7174
- PMC
- PMC11660821
- OpenAlex
- W4387660773
- Cited by
- 11
- References
- 17
- Citations by year
- 2026: 5 · 2025: 3 · 2024: 3
- FWCI
- 2.24
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- Locations
- Research on Child and Adolescent Psychopathology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Health (R01 MH120109, K23 MH108656, R37 MH059105)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Neuropsychology and Physiological Psychology › Developmental and Educational Neuropsychology
- Keywords
- attention deficit hyperactivity disorder, emotional dysregulation, error monitoring, adolescents, error-related negativity, error positivity, negative affect, emotional go/no-go task, EEG, latent profile analysis, Research Domain Criteria, diagnostic heterogeneity, neural markers
- MeSH terms
- Adolescent, Attention Deficit Disorder with Hyperactivity, Electroencephalography, Emotions, Humans, Mental Processes, Temperament
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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