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Cited by 464Autism Spectrum Disorder ResearchChild Nutrition and Feeding IssuesChild and Adolescent Psychosocial and Emotional Development

The DOI matches its Crossref record; 65 of the 67 references it cites were found in a registry or an index.

The Heavy Burden of Psychiatric Comorbidity in Youth with Autism Spectrum Disorders: A Large Comparative Study of a Psychiatrically Referred Population

Joshi, Gagan, Petty, Carter, Wozniak, Janet, Henin, Aude, Fried, Ronna, Galdo, Maribel, Kotarski, Meghan, Walls, Sarah, Biederman, Joseph·2010·Journal of Autism and Developmental Disorders
DOI 10.1007/s10803-010-0996-9
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Abstract

The objective of the study was to systematically examine patterns of psychiatric comorbidity in referred youth with autism spectrum disorders (ASD) including autistic disorder and pervasive developmental disorder not otherwise specified. Consecutively referred children and adolescents to a pediatric psychopharmacology program were assessed with structured diagnostic interview and measures of psychosocial functioning. Comparisons were made between those youth satisfying diagnostic criteria for ASD and age and sex matched youth without ASD referred to the same clinical program. 9.3% (217/2323) of the referred youth (age range: 3-17 years) met DSM-III-R criteria for ASD. ASD youth suffered from significantly higher number of comorbid disorders than comparisons (6.4 ± 2.7 vs. 5.2 ± 2.9; p < 0.001). Ninety-five percent of the youth with ASD had three or more comorbid psychiatric disorders and 74% had five or more comorbid disorders. ASD youth were also more functionally impaired and required extra-assistance in school and therapeutic interventions at higher rates than age and sex matched non-ASD referred youth. Youth with ASD have high levels of psychiatric comorbidity and dysfunction comparable to the referred population of youth without ASD. These findings emphasize the heavy burden of psychiatric comorbidity afflicting youth with ASD and may be important targets for intervention.

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Research works printed but not linked: 7

  1. American Psychiatric Association. (1987). Diagnostic and statistical manual of mental disorders: Third edition text revision (DSM-III-R). Washington, DC: American Psychiatric Association.
  2. American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders: Fourth edition (DSM-IV). Washington, DC: American Psychiatric Association.
  3. CDC. (2006). Parental report of diagnosed autism in children aged 4–17 years. MMWR, 55, 481–486.
  4. Orvaschel, H. (1994). Schedule for affective disorder and schizophrenia for school-age children epidemiologic version. Ft. Lauderdale: Nova Southeastern University, Center for Psychological Studies.
  5. Orvaschel, H., & Puig-Antich, J. (1987). Schedule for Affective Disorders and Schizophrenia for School-Age Children: Epidemiologic Version. Fort Lauderdale, FL: Nova University.
  6. StataCorp. (2007). Stata statistical software: Release 10. College Station, TX: StataCorp LP.
  7. Wozniak, J., Biederman, J., Faraone, S., & Al, E. (1997a). Mania in children with pervasive developmental disorder revisited. Journal of the American Academy of Child and Adolescent Psychiatry, 36, 1552–1559.

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Metadata

Authors
Joshi, G., Petty, C., Wozniak, J., Henin, A., Fried, R., Galdo, M., Kotarski, M., Walls, S., & Biederman, J.
Affiliations
  • Harvard University (US)
  • Massachusetts General Hospital (US)
Corresponding author
Joshi, Gagan
ORCID
Venue
Journal of Autism and Developmental Disorders
Publisher
Springer Science and Business Media LLC
Published
2010-03-23
Volume
40
Issue
11
Pages
1361-1370
ISSN
  • 0162-3257 (ISSN-L)
  • 1573-3432
DOI
10.1007/s10803-010-0996-9
OpenAlex
W2058684270
Cited by
464
References
67
Citations by year
2026: 15 · 2025: 17 · 2024: 30 · 2023: 28 · 2022: 37 · 2021: 48 · 2020: 47 · 2019: 40 · 2018: 32 · 2017: 37 · 2016: 20 · 2015: 37 · 2014: 25 · 2013: 21 · 2012: 19
FWCI
9.67
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (tdm)
Locations
  • Journal of Autism and Developmental Disorders (publishedVersion)
  • PubMed (publishedVersion)
Funders
Centers for Disease Control and Prevention
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
  • Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
  • Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
Keywords
autism spectrum disorder, psychiatric comorbidity, pervasive developmental disorder not otherwise specified, autistic disorder, children and adolescents, psychosocial functioning, functional disability, therapeutic interventions, psychiatric referral, pediatric psychopharmacology
MeSH terms
Adolescent, Autistic Disorder, Mental Disorders, Child, Child Development Disorders, Pervasive, Child, Preschool, Female, Humans, Male, Psychiatric Status Rating Scales, Referral and Consultation, Comorbidity, Case-Control Studies, Cost of Illness, Diagnostic and Statistical Manual of Mental Disorders

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