Psychiatric Comorbidity and Functioning in a Clinically Referred Population of Adults with Autism Spectrum Disorders: A Comparative Study
Abstract
To systematically examine the patterns of psychiatric comorbidity and functioning in clinically referred adults with autism spectrum disorders (ASD). Psychiatrically referred adults with and without ASD were compared on measures assessing for psychiatric comorbidity and psychosocial functioning. Sixty-three adults with ASD participated in the study (mean age: 29 ± 11 years). Adults with ASD in their lifetime suffered from a higher burden of psychiatric disorders (6 ± 3.4 vs. 3.5 ± 2.7; p < 0.001) including major depressive disorder and multiple anxiety disorders, and were functionally more impaired with a significant proportion having received both counseling and pharmacotherapy. Adults with ASD have high levels of psychiatric comorbidity and dysfunction comparable to a clinically referred population of adults without ASD.
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Autistic people are more likely to experience multiple anxiety disorders concurrently.
“autistic people are more likely to experience multiple anxiety disorders concurrently (Joshi et al., 2013).”
This sample presented with complex and pervasive anxiety difficulties, consistent with other studies, as well as other co-occurring physical and mental health conditions.
“This sample presented with complex and pervasive anxiety difficulties, consistent with other studies (Joshi et al., 2013) as well as other co-occurring physical and mental health conditions.”
A flexible and individualised manualised approach to treating anxiety experienced by autistic people shows promise, especially given the experience of multiple concurrent anxiety disorders in this sample and other research.
“A flexible and individualised manualised approach to treating anxiety experienced by autistic people shows promise, especially given the experience of multiple concurrent anxiety disorders in this sample and other research (e.g., Joshi et al., 2013).”
Autistic individuals experience greater rates of anxiety than same-aged peers without autism.
“Research suggests that autistic individuals1 experience greater rates of anxiety than same-aged peers without autism (e.g. Croen et al., 2015; Joshi et al., 2013; Roux et al., 2017; Russell et al., 2016).”
From Listening to the autistic voice: Mental health priorities to guide research and practice in autism from a stakeholder-driven project (2020) · cites this paper as Joshi et al., 2013
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“This sample presented with complex and pervasive anxiety difficulties, consistent with other studies (Joshi et al., 2013) as well as other co-occurring physical and mental health conditions.”
BackgroundResultInfluential
- Authors
- Joshi, G., Wozniak, J., Petty, C., Martelon, M. K., Fried, R., Bolfek, A., Kotte, A., Stevens, J., Furtak, S. L., Bourgeois, M., Caruso, J., Caron, A., & Biederman, J.
- Affiliations
- Harvard University (US)
- Boston Children's Hospital (US)
- Massachusetts General Hospital (US)
- Corresponding author
- Joshi, Gagan
- Venue
- Journal of Autism and Developmental Disorders
- Published
- 2012-10-18
- Volume
- 43
- Issue
- 6
- Pages
- 1314-1325
- ISSN
- 0162-3257 (ISSN-L)
- 1573-3432
- OpenAlex
- W1993632475
- Cited by
- 419
- References
- 63
- Citations by year
- 2026: 17 · 2025: 21 · 2024: 33 · 2023: 33 · 2022: 39 · 2021: 49 · 2020: 46 · 2019: 47 · 2018: 28 · 2017: 30 · 2016: 26 · 2015: 29 · 2014: 10 · 2013: 11
- FWCI
- 8.18
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Autism and Developmental Disorders (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Social Sciences › Psychology › Clinical Psychology › Family and Disability Support Research
- Keywords
- autism spectrum disorder, psychiatric comorbidity, psychosocial functioning, major depressive disorder, anxiety disorders, autistic adults, clinical referral, functional disability, counseling, pharmacotherapy
- MeSH terms
- Adolescent, Adult, Mental Disorders, Child, Child Development Disorders, Pervasive, Major Depressive Disorder, Female, Humans, Male, Middle Aged, Comorbidity, Young Adult
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