The DOI matches its Crossref record; 65 of the 65 references it cites were found in a registry or an index.
Psychiatric Comorbidity and Medication Use in Adults with Autism Spectrum Disorder
Open accessAbstract
The purpose of this study was to investigate comorbid psychiatric disorders and psychotropic medication use among adults with autism spectrum disorder (ASD) ascertained as children during a 1980's statewide Utah autism prevalence study (n = 129). Seventy-three individuals (56.6 %) met criteria for a current psychiatric disorder; 89 participants (69.0 %) met lifetime criteria for a psychiatric disorder. Caregivers reported a psychiatric diagnosis in 44 participants (34.1 %). Anxiety disorder had the highest current and lifetime prevalence (39.5 and 52.7 %, respectively). Participants with intellectual disability (n = 94, 72.8 %) were significantly less likely to have community-based diagnoses of anxiety (χ(2) = 5.37, p = 0.02) or depression (χ(2) = 13.18, p < 0.001) reported by caregivers. Seventy-six participants (58.9 %) were taking ≥1 psychotropic medication. Comorbid psychiatric disorders occur frequently in adults with ASD, though identifying these disorders poses a challenge in community settings. A greater understanding of the presentation of these conditions within this population will increase assessment validity and the potential for efficacious intervention.
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“The majority of autistic children, adolescents and adults have one or more associated mental health conditions (Buck et al., 2014; Simonoff et al., 2008), with co-occurring anxiety disorders among the most common concerns.”
From Self-guided mindfulness and cognitive behavioural practices reduce anxiety in autistic adults: A pilot 8-month waitlist-controlled trial of widely available online tools. (2020) · cites this paper as Buck et al., 2014
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“Although prevalence estimates vary across studies, the current consensus is that 40%–50% of autistic individuals meet formal criteria for a co-occurring anxiety disorder (Buck et al., 2014; Van Steensel et al., 2011)”
From Self-guided mindfulness and cognitive behavioural practices reduce anxiety in autistic adults: A pilot 8-month waitlist-controlled trial of widely available online tools. (2020) · cites this paper as Buck et al., 2014
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“Our results are, to a great extent, in line with the earlier studies on adults with ASD, which have shown that concomitant psychiatric symptoms and diagnoses are common”
From Older Adults with Autism Spectrum Disorders in Sweden: A Register Study of Diagnoses, Psychiatric Care Utilization and Psychotropic Medication of 601 Individuals (2018) · cites this paper as Buck et al. 2014
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“with co-occurring anxiety disorders among the most common concerns.”
From Self-guided mindfulness and cognitive behavioural practices reduce anxiety in autistic adults: A pilot 8-month waitlist-controlled trial of widely available online tools. (2020) · cites this paper as Buck et al., 2014
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Citations
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Adapting Measures of Anxiety and Mood Disorders for Use with Autistic Adults: A Systematic Review
Wilkinson, E. H., Brewe, A. M., Hastings, R. P., Jahoda, A. J., White, S. W., & Bal, V. H. (2026) · Current Developmental Disorders Reports · doi:10.1007/s40474-026-00348-3
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Altered cerebrospinal fluid-based clearance mechanisms in aging autistic adultsPreprint
Christensen, D., Barisano, G., Wilkes, B. J., Shin, Y. S., Wang, J., Parks, E., Orlando, A., Karmakar, B., Coombes, S. A., Sotgiu, S., et al. (2026) · Research Square · doi:10.21203/rs.3.rs-9450979/v1
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Graziosi, S. G. S., Oliver, E., Arline, V., Mahler, K., Ratcliff, K., Pryor, L., & Hilton, C. L. (2026) · Occupational Therapy International · doi:10.1155/oti/4437761
Metadata
- Authors
- Buck, T. R., Viskochil, J., Farley, M., Coon, H., McMahon, W. M., Morgan, J., & Bilder, D. A.
- Affiliations
- University of Utah (US)
- University of Wisconsin–Madison (US)
- Corresponding author
- Bilder, Deborah A.
- Venue
- Journal of Autism and Developmental Disorders
- Published
- 2014-06-24
- Volume
- 44
- Issue
- 12
- Pages
- 3063-3071
- ISSN
- 0162-3257 (ISSN-L)
- 1573-3432
- PMC
- PMC4355011
- OpenAlex
- W1997388980
- Cited by
- 323
- References
- 65
- Citations by year
- 2026: 7 · 2025: 17 · 2024: 32 · 2023: 24 · 2022: 27 · 2021: 43 · 2020: 34 · 2019: 50 · 2018: 21 · 2017: 27 · 2016: 19 · 2015: 19 · 2014: 2
- FWCI
- 12.46
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Autism and Developmental Disorders (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Autism Speaks
- University of Utah
- National Institutes of Health
- National Institute of Mental Health (R01MH094400)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Down syndrome and intellectual disability research
- Keywords
- autism spectrum disorder, psychiatric comorbidity, psychotropic drug use, anxiety disorders, depression, intellectual disability, autistic adults, community diagnosis
- MeSH terms
- Adolescent, Adult, Mental Disorders, Child, Child Development Disorders, Pervasive, Child, Preschool, Female, Follow-Up Studies, Humans, Longitudinal Studies, Male, Middle Aged, Population Surveillance, Psychotropic Drugs, Utah, Cohort Studies, Comorbidity, Young Adult
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