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Psychiatric Comorbidity and Medication Use in Adults with Autism Spectrum Disorder

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Buck, Tara R., Viskochil, Joseph, Farley, Megan, Coon, Hilary, McMahon, William M., Morgan, Jubel, Bilder, Deborah A.·2014·Journal of Autism and Developmental Disorders

DOI 10.1007/s10803-014-2170-2PMC PMC4355011

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Abstract

The purpose of this study was to investigate comorbid psychiatric disorders and psychotropic medication use among adults with autism spectrum disorder (ASD) ascertained as children during a 1980's statewide Utah autism prevalence study (n = 129). Seventy-three individuals (56.6 %) met criteria for a current psychiatric disorder; 89 participants (69.0 %) met lifetime criteria for a psychiatric disorder. Caregivers reported a psychiatric diagnosis in 44 participants (34.1 %). Anxiety disorder had the highest current and lifetime prevalence (39.5 and 52.7 %, respectively). Participants with intellectual disability (n = 94, 72.8 %) were significantly less likely to have community-based diagnoses of anxiety (χ(2) = 5.37, p = 0.02) or depression (χ(2) = 13.18, p < 0.001) reported by caregivers. Seventy-six participants (58.9 %) were taking ≥1 psychotropic medication. Comorbid psychiatric disorders occur frequently in adults with ASD, though identifying these disorders poses a challenge in community settings. A greater understanding of the presentation of these conditions within this population will increase assessment validity and the potential for efficacious intervention.

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Authors: Buck, T. R., Viskochil, J., Farley, M., Coon, H., McMahon, W. M., Morgan, J., & Bilder, D. A.
Affiliations: University of Utah (US)
University of Wisconsin–Madison (US)
Corresponding author: Bilder, Deborah A.
ORCID: Buck, Tara R.
Farley, Megan
Coon, Hilary
Bilder, Deborah A.
Venue: Journal of Autism and Developmental Disorders
Publisher: Springer Science and Business Media LLC
Published: 2014-06-24
Volume: 44
Issue: 12
Pages: 3063-3071
ISSN: 0162-3257 (ISSN-L)
1573-3432
DOI: 10.1007/s10803-014-2170-2
PMC: PMC4355011
OpenAlex: W1997388980
Cited by: 323
References: 65
Citations by year: 2026: 7 · 2025: 17 · 2024: 32 · 2023: 24 · 2022: 27 · 2021: 43 · 2020: 34 · 2019: 50 · 2018: 21 · 2017: 27 · 2016: 19 · 2015: 19 · 2014: 2
FWCI: 12.46
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.springer.com/tdm (tdm)
Locations: Journal of Autism and Developmental Disorders (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: Autism Speaks
University of Utah
National Institutes of Health
National Institute of Mental Health (R01MH094400)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Down syndrome and intellectual disability research
Keywords: autism spectrum disorder, psychiatric comorbidity, psychotropic drug use, anxiety disorders, depression, intellectual disability, autistic adults, community diagnosis
MeSH terms: Adolescent, Adult, Mental Disorders, Child, Child Development Disorders, Pervasive, Child, Preschool, Female, Follow-Up Studies, Humans, Longitudinal Studies, Male, Middle Aged, Population Surveillance, Psychotropic Drugs, Utah, Cohort Studies, Comorbidity, Young Adult

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Psychiatric Comorbidity and Medication Use in Adults with Autism Spectrum Disorder

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