Dextrins from Maize Starch as Substances Activating the Growth of Bacteroidetes and Actinobacteria Simultaneously Inhibiting the Growth of Firmicutes, Responsible for the Occurrence of Obesity
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Unarguably, diet has a significant impact on human intestinal microbiota. The role of prebiotics as substances supporting the maintenance of appropriate body weight and reducing the demand for energy via stimulation of the growth of beneficial microbiota of the gut and formation products such as short-chain fatty acids, is more and more often highlighted. The objective of this study was to evaluate whether dextrins from maize starch resistant to enzymatic digestion stimulate the growth of Bacteroidetes and Actinobacteria strains representing a majority of the population of colon microbiota in lean individuals and limit the growth of Firmicutes bacterial strains representing a majority of the population of colon microbiota in obese individuals. The study was conducted with the use of in vitro method, using isolates from faeces of children characterized by normal weight, overweight and obesity. It was demonstrated that dextrins from maize starch equally efficient stimulate the growth of the isolates derived from normal-weight, overweight and obese children, and therefore may be added to foods as a beneficial component stimulating growth of strains belonging to Actinobacteria and Bacteroidetes for both overweight, obese and normal-weight children.
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Dextrin is a polysaccharide similar to fructan and can stimulate the growth of probiotic strains such as Actinobacteria and Bacteroidetes and reduce pathogenic bacteria.
“Dextrin was used as positive control because dextrin is a polysaccharide [25], similar to fructan, and can stimulate the growth of probiotic strains such as Actinobacteria and Bacteroidetes [26], and reduced numbers of pathogenic bacteria [27].”
From Preventive Effects and Mechanisms of Garlic on Dyslipidemia and Gut Microbiome Dysbiosis (2019) · cites this paper as [26]
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- Authors
- Barczynska, R., Kapusniak, J., Litwin, M., Slizewska, K., & Szalecki, M.
- Venue
- Plant Foods for Human Nutrition
- Published
- 2016-05-07
- Volume
- 71
- Issue
- 2
- Pages
- 190-196
- ISSN
- 0033-5134 (ISSN-L)
- 0921-9668
- 1573-9104
- PMC
- PMC4891389
- OpenAlex
- W2361174213
- Cited by
- 60
- References
- 29
- Citations by year
- 2025: 8 · 2024: 9 · 2023: 4 · 2022: 9 · 2021: 5 · 2020: 10 · 2019: 6 · 2018: 5 · 2017: 3 · 2016: 1
- FWCI
- 2.60
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Plant Foods for Human Nutrition (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
- Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
- Keywords
- dextrin, corn starch, prebiotics, Bacteroidetes, actinobacteria, Firmicutes, gut microbiota, obesity, overweight children, short-chain fatty acids, dietary fiber, resistant starch, in vitro bacterial growth
- MeSH terms
- Firmicutes, Bacillota, Child, Zea mays, Dextrins, Diet, Fatty Acids, Volatile, Feces, Female, Humans, Male, Actinobacteria, Bacteroidetes, Gastrointestinal Tract, Overweight, Prebiotics, Microbiota
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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