Cited by 60Gut microbiota and healthMicrobial Metabolites in Food BiotechnologyInfant Nutrition and Health

Dextrins from Maize Starch as Substances Activating the Growth of Bacteroidetes and Actinobacteria Simultaneously Inhibiting the Growth of Firmicutes, Responsible for the Occurrence of Obesity

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Barczynska, Renata, Kapusniak, Janusz, Litwin, Mieczyslaw, Slizewska, Katarzyna, Szalecki, Mieczyslaw·2016·Plant Foods for Human Nutrition

Abstract

Unarguably, diet has a significant impact on human intestinal microbiota. The role of prebiotics as substances supporting the maintenance of appropriate body weight and reducing the demand for energy via stimulation of the growth of beneficial microbiota of the gut and formation products such as short-chain fatty acids, is more and more often highlighted. The objective of this study was to evaluate whether dextrins from maize starch resistant to enzymatic digestion stimulate the growth of Bacteroidetes and Actinobacteria strains representing a majority of the population of colon microbiota in lean individuals and limit the growth of Firmicutes bacterial strains representing a majority of the population of colon microbiota in obese individuals. The study was conducted with the use of in vitro method, using isolates from faeces of children characterized by normal weight, overweight and obesity. It was demonstrated that dextrins from maize starch equally efficient stimulate the growth of the isolates derived from normal-weight, overweight and obese children, and therefore may be added to foods as a beneficial component stimulating growth of strains belonging to Actinobacteria and Bacteroidetes for both overweight, obese and normal-weight children.

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  • Dextrin is a polysaccharide similar to fructan and can stimulate the growth of probiotic strains such as Actinobacteria and Bacteroidetes and reduce pathogenic bacteria.

    “Dextrin was used as positive control because dextrin is a polysaccharide [25], similar to fructan, and can stimulate the growth of probiotic strains such as Actinobacteria and Bacteroidetes [26], and reduced numbers of pathogenic bacteria [27].”

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  1. [10]Backhed F Manchester JK Semenkovich CF Mechanism underlying the resistance to diet-included in germ-free mice Proc Natl Acad Sci 2007 101 15718 15723 10.1073/pnas.0407076101 17210919 PMC1764762 · DOI · Paper page

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Authors
Barczynska, R., Kapusniak, J., Litwin, M., Slizewska, K., & Szalecki, M.
Venue
Plant Foods for Human Nutrition
Published
2016-05-07
Volume
71
Issue
2
Pages
190-196
ISSN
  • 0033-5134 (ISSN-L)
  • 0921-9668
  • 1573-9104
OpenAlex
W2361174213
Cited by
60
References
29
Citations by year
2025: 8 · 2024: 9 · 2023: 4 · 2022: 9 · 2021: 5 · 2020: 10 · 2019: 6 · 2018: 5 · 2017: 3 · 2016: 1
FWCI
2.60
Type
journal article
Language
en
Open access
Locations
  • Plant Foods for Human Nutrition (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
  • Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
  • Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
Keywords
dextrin, corn starch, prebiotics, Bacteroidetes, actinobacteria, Firmicutes, gut microbiota, obesity, overweight children, short-chain fatty acids, dietary fiber, resistant starch, in vitro bacterial growth
MeSH terms
Firmicutes, Bacillota, Child, Zea mays, Dextrins, Diet, Fatty Acids, Volatile, Feces, Female, Humans, Male, Actinobacteria, Bacteroidetes, Gastrointestinal Tract, Overweight, Prebiotics, Microbiota

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