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Reliability and validity of the Infant and Toddler Quality of Life Questionnaire (ITQOL) in a general population and respiratory disease sample
Open accessAbstract
OBJECTIVE: To evaluate feasibility, internal consistency, test-retest reliability, and concurrent and discriminative validity of the Infant and Toddler Quality of Life Questionnaire (ITQOL) for parents of pre-school children with 12 scales (103-items) covering physical and psychosocial domains and impact of child health on parents, in comparison with the TNO-AZL Pre-school Children Quality of Life Questionnaire (TAPQOL). METHODS: Parents of children from a random general population sample (2 months-4 years old; n = 500) and of an outpatient clinic sample of children with respiratory disease (5 months-[Formula: see text] years old; n = 217) were mailed ITQOL and TAPQOL questionnaires; a retest was sent after two weeks. RESULTS: Feasibility: The response was >or=80% with few missing and non-unique ITQOL-answers (<2%) in both study populations. Some ITQOL-scales (3-4 scales) showed a ceiling effect (>25% at maximum score). Internal consistency: All Cronbach's alpha >0.70. Test-retest Intraclass Correlation Coefficients (ICCs) were moderate or adequate (>or=0.50; p < 0.01) for 10 ITQOL-scales. VALIDITY: ITQOL-scales, with a few exceptions, correlated better with predefined parallel TAPQOL scales than with non-parallel scales. Five to eight ITQOL-scales discriminated clearly between children with few and with many parent-reported chronic conditions, between children with and without doctor-diagnosed respiratory disease and with a low and a high parent-reported medical consumption (p < 0.05). CONCLUSIONS: This study supported the evidence that the ITQOL is a feasible instrument with adequate psychometric properties. The study provided reference ITQOL scores for gender/age subgroups. We recommend repeated evaluations of the ITQOL in varied populations, especially among very young children, including repeated assessments of test-retest characteristics and evaluations of responsiveness to change. We recommend developing and evaluating a shortened ITQOL version.
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Metadata
- Authors
- Raat, H., Landgraf, J. M., Oostenbrink, R., Moll, H. A., & Essink-Bot, M.-L.
- Affiliations
- Erasmus MC (NL)
- Corresponding author
- Raat, Hein
- Venue
- Quality of Life Research
- Published
- 2006-11-17
- Volume
- 16
- Issue
- 3
- Pages
- 445-460
- ISSN
- 0962-9343 (ISSN-L)
- 1573-2649
- PMC
- PMC2792359
- OpenAlex
- W2053572857
- Cited by
- 187
- References
- 36
- Citations by year
- 2026: 6 · 2025: 8 · 2024: 5 · 2023: 15 · 2022: 10 · 2021: 11 · 2020: 7 · 2019: 12 · 2018: 13 · 2017: 7 · 2016: 11 · 2015: 7 · 2014: 7 · 2013: 11 · 2012: 8
- FWCI
- 15.94
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Quality of Life Research (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (publishedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
- RePub (Erasmus University Rotterdam) (submittedVersion, other-oa)
- Funders
- ZonMw (22000128)
- Erasmus Universitair Medisch Centrum Rotterdam
- Topics
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Childhood Cancer Survivors' Quality of Life
- Health Sciences › Nursing › Research and Theory › Health Education and Validation
- Keywords
- quality of life, preschool children, respiratory diseases, psychometric properties, test-retest reliability, concurrent validity, discriminant validity, parent-reported quality of life, ceiling effect, health care utilization, psychosocial health
- MeSH terms
- Asthma, Child Welfare, Child, Preschool, Feasibility Studies, Female, Humans, Infant, Infant Welfare, Male, Netherlands, Psychometrics, Quality of Life, Surveys and Questionnaires, Respiratory Tract Diseases, Sickness Impact Profile, Proxy
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