Measuring fatigue in persons with multiple sclerosis: creating a crosswalk between the Modified Fatigue Impact Scale and the PROMIS Fatigue Short Form
Abstract
Purpose To create cross-walk tables to associate scores for the Modified Fatigue Impact Scale (MFIS) with scores for the Patient Reported Outcome Measurement Information System (PROMIS) Fatigue Short Form (SF) in persons with Multiple Sclerosis (MS). Methods Cross-walk tables were created using equipercentile linking and based on data collected at one time point in a longitudinal study of persons with MS (N = 458). Validation of the tables was conducted using data collected at a subsequent time point (N = 444). Deviations between estimates and actual scores were compared across levels of fatigue. The impact of sample size on the precision of sample mean estimates was evaluated using bootstrapping. Results Correlations between deviations and fatigue level for the PROMIS Fatigue SF and MFIS were (-0.31) and (-0.30), respectively, indicating moderately greater deviations with lower fatigue scores. Estimated sample means were impacted by sample size. Conclusions Cross-walk tables allow data from studies using different measures of fatigue to be combined to achieve larger sample sizes and to compare results. These tables are valid for group-level analyses with sample sizes of 150 or greater.
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Daily Fatigue was assessed with the PROMIS fatigue 6-item short-form, which has demonstrated validity across conditions and ecological validity when administered in diary format, and has been linked to legacy fatigue measures in MS.
“Daily Fatigue was assessed with the PROMIS fatigue 6-item short-form, which has demonstrated validity across conditions63,65,66 and ecological validity when administered in diary format67, and has been linked to legacy fatigue measures in MS66.”
From Ecological momentary assessment of pain, fatigue, depressive, and cognitive symptoms reveals significant daily variability in multiple sclerosis (2017) · cites this paper as [65]
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Cella, D., Riley, W., Stone, A., Rothrock, N., Reeve, B., Yount, S., Amtmann, D., Bode, R., Buysse, D., Choi, S., et al. (2010) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2010.04.011 · Cited by 5,128 · see citing works
Self-citationThe impact of fatigue on patients with multiple sclerosis
Fisk, J. D., Pontefract, A., Ritvo, P. G., Archibald, C. J., & Murray, T. J. (1994) · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · doi:10.1017/s0317167100048691 · Cited by 1,025 · see citing works
Evaluation of the modified fatigue impact scale in four different European countries
Kos, D., Kerckhofs, E., Carrea, I., Verza, R., Ramos, M., & Jansa, J. (2005) · Multiple Sclerosis Journal · doi:10.1191/1352458505ms1117oa · Cited by 381 · see citing works
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Choi, S. W., Schalet, B., Cook, K. F., & Cella, D. (2014) · Psychological Assessment · doi:10.1037/a0035768 · Cited by 480 · see citing works
Self-citationRapid, responsive, relevant (R3) research: a call for a rapid learning health research enterprise
Riley, W. T., Glasgow, R. E., Etheredge, L., & Abernethy, A. P. (2013) · Clinical and Translational Medicine · doi:10.1186/2001-1326-2-10 · Cited by 267 · see citing works
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Askew, R. L., Kim, J., Chung, H., Cook, K. F., Johnson, K. L., & Amtmann, D. (2013) · Quality of Life Research · doi:10.1007/s11136-013-0398-5 · Cited by 60 · see citing works
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- Authors
- Noonan, V. K., Cook, K. F., Bamer, A. M., Choi, S. W., Kim, J., & Amtmann, D.
- Affiliations
- University of Washington (US)
- Northwestern University (US)
- Corresponding author
- Noonan, Vanessa K.
- Venue
- Quality of Life Research
- Published
- 2011-11-03
- Volume
- 21
- Issue
- 7
- Pages
- 1123-1133
- ISSN
- 0962-9343 (ISSN-L)
- 1573-2649
- OpenAlex
- W2073160627
- Cited by
- 54
- References
- 3
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 2 · 2023: 3 · 2022: 6 · 2021: 1 · 2020: 2 · 2019: 4 · 2018: 3 · 2017: 3 · 2016: 3 · 2015: 9 · 2014: 3 · 2013: 8 · 2012: 2
- FWCI
- 2.92
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Quality of Life Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Public Health Service (H133B031129, H133B080025)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (U01AR052171)
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Multiple Sclerosis Research Studies
- Social Sciences › Decision Sciences › Management Science and Operations Research › Psychometric Methodologies and Testing
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Keywords
- multiple sclerosis, fatigue, Modified Fatigue Impact Scale, equipercentile linking, patient-reported outcome measures, measurement invariance, sample size effects, bootstrapping
- MeSH terms
- Adult, Fatigue, Female, Humans, Longitudinal Studies, Male, Middle Aged, Multiple Sclerosis, Reference Values, Severity of Illness Index, Sickness Impact Profile
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