ADHD burden of illness in older adults: a life course perspective
Abstract
Purpose To explore the burden of illness and impact on patients' quality of life (QoL) experiences in older ADHD adults. Methods Telephone interviews were conducted with older adult participants diagnosed with ADHD later in life. Transcripts were analyzed following a grounded theory approach. Results Mean age of participants (N = 24) was 66 years, and mean age at diagnosis was 57 years; 68% were men and 63% reported other comorbid mental health conditions. ADHD symptoms reported were inattention (71%), impulsivity (58%), hyperactivity (54%), and disorganization (54%). The majority of participants (63%) experienced an accumulated lifetime burden of illness and reported being financially less-well-off, had lower educational achievement, job performance, and greater social isolation due to their ADHD. Older adults reported significantly greater impairments in productivity (P ≤ 0.02) and a better life outlook (P ≤ 0.05) than younger ADHD adults. Conclusions Older adults' QoL suffers from the accumulative negative impact of ADHD symptoms/impairments on their professional, economic, social, and emotional well-being.
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Older adults with ADHD report more partnership problems, higher rates of being divorced or never married, more emotional and social loneliness, more financial problems and lower lifetime productivity, as well as reduced health-related quality of life and reduced satisfaction with life compared to older individuals without ADHD.
“For example, older adults with ADHD report about more partnership problems, higher rates of being divorced or never being married, more emotional and social loneliness, more financial problems and lower lifetime productivity, as well as a reduced health-related quality of life and reduced satisfaction with life compared to older individuals without ADHD (Michielsen et al. 2015; Brod et al. 2012; L”
From ADHD and associated psychopathology in older adults in a German community sample (2023) · cites this paper as Brod et al. 2012
Clinical presentation of ADHD may change with age, with inattentive symptoms becoming more prevalent than hyperactivity and impulsivity.
“Clinical presentation of ADHD may change with age, with inattentive symptoms becoming more prevalent than hyperactivity and impulsivity (Lensing et al., 2015;Brod et al., 2012).”
From Prevalence of attention-deficit/hyperactivity disorder in older adults: a systematic review and meta-analysis (2020) · cites this paper as Brod et al., 2012
Older patients and/or their medical care providers may have concerns about potential ADHD medication side effects because of older age, comorbid psychiatric and somatic disorders (in particular cardiovascular conditions), and interactions with other medications.
“Additionally, older patients and/or their medical care providers may have concerns regarding potential ADHD medication side effects due to older age, comorbid psychiatric and somatic disorders (in particular cardiovascular conditions), and interactions with other medications (Goodman et al., 2016;Lensing et al., 2015;Brod et al., 2012;Herrmann et al., 2008).”
From Prevalence of attention-deficit/hyperactivity disorder in older adults: a systematic review and meta-analysis (2020) · cites this paper as Brod et al., 2012
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Müller, M., Turner, D., Barra, S., Rösler, M., & Retz, W. (2023) · Journal of Neural Transmission · doi:10.1007/s00702-022-02584-4 · Cited by 10 · see citing works
- Authors
- Brod, M., Schmitt, E., Goodwin, M., Hodgkins, P., & Niebler, G.
- Affiliations
- Brod Group (US)
- Institute on Aging (US)
- University of California, Berkeley (US)
- Takeda (United States) (US)
- Corresponding author
- Brod, Meryl
- ORCID
- Brod, Meryl
- Venue
- Quality of Life Research
- Published
- 2011-07-30
- Volume
- 21
- Issue
- 5
- Pages
- 795-799
- ISSN
- 0962-9343 (ISSN-L)
- 1573-2649
- OpenAlex
- W1978820857
- Cited by
- 135
- References
- 8
- Citations by year
- 2026: 10 · 2025: 8 · 2024: 7 · 2023: 14 · 2022: 7 · 2021: 3 · 2020: 9 · 2019: 10 · 2018: 12 · 2017: 10 · 2016: 9 · 2015: 11 · 2014: 8 · 2013: 9 · 2012: 7
- FWCI
- 5.25
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Quality of Life Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
- Keywords
- adult ADHD, older adults, disease burden, quality of life, life course, inattention, impulsivity, hyperactivity, disorganization, psychiatric comorbidity, social isolation, financial hardship, educational attainment, employee performance
- MeSH terms
- Adaptation, Psychological, Age Factors, Aged, Aged, 80 and over, Aging, Attention Deficit Disorder with Hyperactivity, Educational Status, Female, Humans, Interview, Psychological, Male, Middle Aged, Pilot Projects, Psychometrics, Quality of Life, Social Isolation, Stress, Psychological, Self Report
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