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Cited by 20Cardiac Health and Mental HealthHealth and Well-being StudiesCancer survivorship and care

The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.

Using path analysis to investigate the relationships between depression, anxiety, and health-related quality of life among patients with coronary artery disease

Lu, Yihua, Jiang, Yun, Gu, Liang·2019·Quality of Life Research
DOI 10.1007/s11136-019-02207-8
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Abstract

Purpose Demographic and clinical indicators usually influence depression, anxiety, and health-related quality of life (HRQoL) in patients with coronary artery disease (CAD). The aim of this study was to assess the direct and indirect association that existed among the identified variables, psychosocial status, and HRQoL in CAD patients.Methods CAD patients with at least one of the main coronary artery and/or branch stenosis over 50% were eligible for inclusion. HRQoL, depression, and anxiety were tested by questionnaires within 3 days after angiography. Mono-factor and multiple linear regression models were used to examine the independent associations of depression, anxiety, and HRQoL. A path analysis was conducted to examine the association among demographic/clinical indicators, depression, anxiety, and HRQoL.Results The sample consisted of 414 subject, patients with depression accounted for 40.82%, and patients with anxiety accounted for 25.12%. The direct effects of SAS scores on HRQoL (B = - 0.26, β = - 0.16), of SDS scores on HRQoL (B = - 0.70, β = - 0.47), of gender on HRQoL (B = 4.05, β = 0.17), and of NYHA classification on HRQoL (B = - 3.46, β = - 0.18) were significant (p < 0.001). The indirect effects of gender on HRQoL (B = 2.16, β = 0.09) and of Gensini scores on HRQoL (B = - 0.06, β = - 0.08) were also statistically significant (p < 0.001).Conclusions Depression and anxiety were common CAD patients and played an important role in HRQoL. Gender differences were found in determinants of HRQoL and the state of depression and anxiety directly, and women's anxiety, depression, and quality of life were worse than men's. NYHA classification and Gensini scores also played direct and indirect role in HRQoL, respectively.

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Metadata

Authors
Lu, Y., Jiang, Y., & Gu, L.
Affiliations
Nantong University (CN)
Corresponding author
Lu, Yihua
ORCID
Venue
Quality of Life Research
Publisher
Springer Science and Business Media LLC
Published
2019-05-16
Volume
28
Issue
10
Pages
2695-2704
ISSN
  • 0962-9343 (ISSN-L)
  • 1573-2649
DOI
10.1007/s11136-019-02207-8
OpenAlex
W2945981661
Cited by
20
References
44
Citations by year
2026: 1 · 2024: 6 · 2023: 5 · 2022: 1 · 2021: 3 · 2020: 4
FWCI
1.46
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Quality of Life Research (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Science and Technology Project of Nantong (MS12016002)
  • Science and Technology Project from Nantong University (13180083)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
  • Social Sciences › Psychology › Clinical Psychology › Health and Well-being Studies
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
Keywords
coronary artery disease, depression, anxiety, health-related quality of life, psychosocial status, gender differences, NYHA functional class, Gensini score, coronary artery stenosis, path analysis
MeSH terms
Anxiety, Coronary Artery Disease, Depression, Female, Humans, Male, Middle Aged, Quality of Life

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