Safety of Pseudomonas chlororaphis as a gene source for genetically modified crops
Open accessAbstract
Genetically modified crops undergo extensive evaluation to characterize their food, feed and environmental safety prior to commercial introduction, using a well-established, science-based assessment framework. One component of the safety assessment includes an evaluation of each introduced trait, including its source organism, for potential adverse pathogenic, toxic and allergenic effects. Several Pseudomonas species have a history of safe use in agriculture and certain species represent a source of genes with insecticidal properties. The ipd072Aa gene from P. chlororaphis encodes the IPD072Aa protein, which confers protection against certain coleopteran pests when expressed in maize plants. P. chlororaphis is ubiquitous in the environment, lacks known toxic or allergenic properties, and has a history of safe use in agriculture and in food and feed crops. This information supports, in part, the safety assessment of potential traits, such as IPD072Aa, that are derived from this source organism.
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Effective toxins have been isolated from other bacteria including species of Pseudomonas and Chromobacter that might be expressed in future insect-resistant GE plants.
“In addition to Bt, effective toxins have also been isolated from other bacteria including species of Pseudomonas (Anderson et al., 2018) and Chromobacter (Sampson et al. 2017) that might be expressed in future insect-resistant GE plants.”
From Genetically engineered crops help support conservation biological control (2019) · cites this paper as Anderson et al., 2018
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Genetically engineered crops help support conservation biological control
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“bacteria including species of Pseudomonas (Anderson et al., 2018) and Chromobacter (Sampson et al.”
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- Authors
- Anderson, J. A., Staley, J., Challender, M., & Heuton, J.
- Affiliations
- Pioneer Hi-Bred (US)
- Corresponding author
- Anderson, Jennifer A.
- Venue
- Transgenic Research
- Published
- 2018-02
- Volume
- 27
- Issue
- 1
- Pages
- 103-113
- ISSN
- 0962-8819 (ISSN-L)
- 1573-9368
- PMC
- PMC5847145
- OpenAlex
- W2792678916
- Cited by
- 44
- References
- 41
- Citations by year
- 2026: 1 · 2025: 6 · 2024: 7 · 2023: 5 · 2022: 2 · 2021: 9 · 2020: 6 · 2019: 5 · 2018: 3
- FWCI
- 5.09
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Transgenic Research (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- U.S. Environmental Protection Agency
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Genetically Modified Organisms Research
- Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural safety and regulations
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Insect Resistance and Genetics
- Keywords
- Pseudomonas chlororaphis, genetically modified crops, safety assessment, insecticidal proteins, maize, allergenicity, toxicity, pathogenicity
- MeSH terms
- Pseudomonas chlororaphis, Bacterial Proteins, Zea mays, Insecticides, Phylogeny, Crops, Agricultural, Plants, Genetically Modified, Biological Control Agents
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