The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Personality and metabolic syndrome
Open accessAbstract
The prevalence of metabolic syndrome has paralleled the sharp increase in obesity. Given its tremendous physical, emotional, and financial burden, it is of critical importance to identify who is most at risk and the potential points of intervention. Psychological traits, in addition to physiological and social risk factors, may contribute to metabolic syndrome. The objective of the present research is to test whether personality traits are associated with metabolic syndrome in a large community sample. Participants (N = 5,662) from Sardinia, Italy, completed a comprehensive personality questionnaire, the NEO-PI-R, and were assessed on all components of metabolic syndrome (waist circumference, triglycerides, high-density lipoprotein cholesterol, blood pressure, and fasting glucose). Logistic regressions were used to predict metabolic syndrome from personality traits, controlling for age, sex, education, and current smoking status. Among adults over age 45 (n = 2,419), Neuroticism and low Agreeableness were associated with metabolic syndrome, whereas high Conscientiousness was protective. Individuals who scored in the top 10% on Conscientiousness were approximately 40% less likely to have metabolic syndrome (OR = 0.61, 95% CI = 0.41-0.92), whereas those who scored in the lowest 10% on Agreeableness were 50% more likely to have it (OR = 1.53, 95% CI = 1.09-2.16). At the facet level, traits related to impulsivity and hostility were the most strongly associated with metabolic syndrome. The present research indicates that those with fewer psychological resources are more vulnerable to metabolic syndrome and suggests a psychological component to other established risk factors.
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“Second, the increasing inclusion of biomarkers in personality-longevity studies is beginning to illuminate biological pathways such as systemic inflammation [65, 66, 218, 219] and artery calcification [220, 221]”
From Personality and Longevity: Knowns, Unknowns, and Implications for Public Health and Personalized Medicine (2011) · cites this paper as [218]
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Grundy, S. M., Bilheimer, D. W., Chait, A., Clark, L. T., Denke, M. A., Havel, R. J., Hazzard, W. R., Hulley, S. B., Hunninghake, D. B., Kreisberg, R. A., et al. (1993) · JAMA · doi:10.1001/jama.269.23.3015 · Cited by 27,944
Detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
Grundy, S. M., Becker, D. M., Clark, L. T., Cooper, R., Denke, M. A., Howard, J. L., Hunninghake, D. B., Illingworth, D. R., Luepker, R. V., McBride, P. E., et al. (2002) · Civil War Book Review · Cited by 12,198
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Metabolic Syndrome and Incident Diabetes
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Research works printed but not linked: 1
- Costa PT Jr, McCrae RR (1992) Revised NEO Personality Inventory (NEO-PI-R) and the NEO Five-Factor Inventory (NEO-FFI) professional manual. Psychological Assessment Resources, Odessa
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Items 101–102 of 102
Unity and Diversity of NEO-PI Personality Profiles of 162 Phenotypes
Ilves, K., Wang, Y. E., Konstabel, K., Adamson, A., Kõrge, K., Raidvee, A., Dagher, A., Mõttus, R., & Vainik, U. (2025) · Personality Science · doi:10.1177/27000710251378408
Gebretsadik, E. T., Aman, A., Lyall, D. M., Tyrrell, J., Hayman, M. M. E., Fajs, N., Lyall, L. M., & Strawbridge, R. J. (2026) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2026.100817
Metadata
- Authors
- Sutin, A. R., Costa, P. T., Uda, M., Ferrucci, L., Schlessinger, D., & Terracciano, A.
- Affiliations
- National Institutes of Health (US)
- National Research Council (IT)
- Corresponding author
- Sutin, Angelina R.
- ORCID
- Venue
- AGE
- Published
- 2010-06-22
- Volume
- 32
- Issue
- 4
- Pages
- 513-519
- ISSN
- 0161-9152 (ISSN-L)
- 1574-4647
- PMC
- PMC2980597
- OpenAlex
- W2161678047
- Cited by
- 102
- References
- 37
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 2 · 2023: 6 · 2022: 5 · 2021: 9 · 2020: 5 · 2019: 5 · 2018: 9 · 2017: 3 · 2016: 6 · 2015: 8 · 2014: 9 · 2013: 10 · 2012: 13
- FWCI
- 10.92
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- AGE (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Institute on Aging (ZIAAG000180, ZIAAG000197, ZIAAG000183)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Personality Traits and Psychology
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Keywords
- metabolic syndrome, personality traits, neuroticism, agreeableness, conscientiousness, impulsivity, hostility, obesity, cardiovascular risk factors, middle-aged and older adults, psychological characteristics
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Blood Glucose, Blood Pressure, Hostility, Humans, Impulsive Behavior, Italy, Cholesterol, HDL, Male, Middle Aged, Obesity, Personality, Personality Inventory, Surveys and Questionnaires, Risk Factors, Triglycerides, Biomarkers, Prevalence, Metabolic Syndrome, Waist Circumference
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