The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Nanoparticles for Applications in Cellular Imaging
Open accessAbstract
In the following review we discuss several types of nanoparticles (such as TiO 2, quantum dots, and gold nanoparticles) and their impact on the ability to image biological components in fixed cells. The review also discusses factors influencing nanoparticle imaging and uptake in live cells in vitro. Due to their unique size-dependent properties nanoparticles offer numerous advantages over traditional dyes and proteins. For example, the photostability, narrow emission peak, and ability to rationally modify both the size and surface chemistry of Quantum Dots allow for simultaneous analyses of multiple targets within the same cell. On the other hand, the surface characteristics of nanometer sized TiO 2 allow efficient conjugation to nucleic acids which enables their retention in specific subcellular compartments. We discuss cellular uptake mechanisms for the internalization of nanoparticles and studies showing the influence of nanoparticle size and charge and the cell type targeted on nanoparticle uptake. The predominant nanoparticle uptake mechanisms include clathrin-dependent mechanisms, macropinocytosis, and phagocytosis.
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Cites
Cancer nanotechnology: opportunities and challenges
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Quantum dot semiconductor nanocrystals for immunophenotyping by polychromatic flow cytometry
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Cited by
Gold Nanorods: From Synthesis and Properties to Biological and Biomedical Applications
Huang, X., Neretina, S., & El‐Sayed, M. A. (2009) · Advanced Materials · doi:10.1002/adma.200802789 · Cited by 1,921
Nanomaterials for Neural Interfaces
Kotov, N. A., Winter, J. O., Clements, I. P., Jan, E., Timko, B. P., Campidelli, S., Pathak, S., Mazzatenta, A., Lieber, C. M., Prato, M., et al. (2009) · Advanced Materials · doi:10.1002/adma.200801984 · Cited by 504
Oh, E., Delehanty, J. B., Sapsford, K. E., Susumu, K., Goswami, R., Blanco-Canosa, J. B., Dawson, P. E., Granek, J., Shoff, M., Zhang, Q., et al. (2011) · ACS Nano · doi:10.1021/nn201624c · Cited by 425
Sajti, C. L., Barchanski, A., Wagener, P., Klein, S., & Barcikowski, S. (2011) · The Journal of Physical Chemistry C · doi:10.1021/jp1093405 · Cited by 33
Metadata
- Authors
- Thurn, K. T., Brown, E., Wu, A., Vogt, S., Lai, B., Maser, J., Paunesku, T., & Woloschak, G. E.
- Venue
- Nanoscale Research Letters
- Published
- 2007-08-15
- Volume
- 2
- Issue
- 9
- Pages
- 430-41
- ISSN
- 1556-276X (ISSN-L)
- OpenAlex
- W2097242510
- Cited by
- 173
- References
- 5
- FWCI
- 5.67
- Type
- journal article
- Language
- en
- Open access
- gold
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