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Investigation of Antidepressant Medication Usage after Bariatric Surgery
Abstract
Background Many patients seeking bariatric surgery have a history of mood disorders and are actively prescribed antidepressants. While extensive documentation exists on the impact of weight loss surgery on reductions in cardiac, diabetic, and hypertensive medications, little is known about the impact of bariatric surgery on the use of antidepressant medications.Methods A retrospective study of 439 patients who had undergone Roux-en-Y gastric bypass (RYGB) from January 2001 to November 2004 was examined for postoperative changes in the use of antidepressant medications.Results After RYGB, 23% of the patients had an increase in their antidepressant use, 40% continued to require the same antidepressant, 18% had a change in antidepressant medication, and only 16% had a decrease or discontinued their antidepressant.Conclusion Unlike most medications, antidepressant usage did not decrease in the majority of patients after RYGB. These results highlight the prevalence of antidepressant prescription use in patients before and after RYGB and support the need for the careful monitoring of depressive symptoms.
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There is some evidence that many patients increase their antidepressant medications after bariatric surgery.
“and there is some evidence that many patients increase their antidepressant medications after having bariatric surgery (67).”
From Behavioral Interventions to Attenuate Driven Overeating and Weight Regain After Bariatric Surgery (2022) · cites this paper as [67]
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Metadata
- Authors
- Cunningham, J. L., Merrell, C. C., Sarr, M., Somers, K. J., McAlpine, D., Reese, M., Stevens, S. R., & Clark, M. M.
- Affiliations
- Mayo Clinic (US)
- Corresponding author
- Cunningham, Julie L.
- Venue
- Obesity Surgery
- Published
- 2011-09-08
- Volume
- 22
- Issue
- 4
- Pages
- 530-535
- ISSN
- 0960-8923 (ISSN-L)
- 1708-0428
- OpenAlex
- W1967672765
- Cited by
- 78
- References
- 36
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 5 · 2023: 5 · 2022: 7 · 2021: 6 · 2020: 5 · 2019: 5 · 2018: 6 · 2017: 3 · 2016: 9 · 2015: 9 · 2014: 8 · 2013: 5 · 2012: 2
- FWCI
- 4.90
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Obesity Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Health Sciences › Medicine › Surgery › Body Contouring and Surgery
- Health Sciences › Medicine › Pharmacology (medical) › Pharmacology and Obesity Treatment
- Keywords
- antidepressants, bariatric surgery
- MeSH terms
- Adolescent, Adult, Aged, Antidepressive Agents, Depression, Female, Follow-Up Studies, Humans, Male, Middle Aged, Obesity, Morbid, Postoperative Period, Drug Prescriptions, Retrospective Studies, United States, Gastric Bypass, Comorbidity, Mood Disorders, Young Adult
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