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Cited by 110Liver Disease Diagnosis and TreatmentBariatric Surgery and OutcomesLiver physiology and pathology

The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.

Effect of Bariatric Surgery on Liver Fibrosis

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Moretto, Myriam, Kupski, Carlos, da Silva, Vinicius Duval, Padoin, Alexandre V., Mottin, Cláudio C.·2012·Obesity Surgery
DOI 10.1007/s11695-011-0559-y
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Abstract

Background Although bariatric surgery has been shown to improve hepatic steatosis in morbidly obese patients, the effect of weight loss on hepatic fibrosis has not been determined. Since the prognosis of patients with nonalcoholic fatty liver disease is closely related to the development of hepatic fibrosis, it is important to determine the hepatic histology of these patients after weight loss. We therefore evaluated the prevalence of hepatic fibrosis in morbidly obese patients undergoing bariatric surgery and assessed the correlation of histologic changes with weight loss. Methods We retrospectively evaluated 78 morbidly obese patients who underwent gastric bypass. Liver biopsies were taken during surgery and after weight loss, and the correlations between histologic findings and hepatic fibrosis were determined. Results Of the 78 patients, 35 (44.8%) had fibrosis at first biopsy, and 24 (30.8%) had hepatic fibrosis after weight loss, including 19 of the 35 patients (54.3%) with fibrosis at first biopsy and 5 of the 43 (11.6%) without hepatic fibrosis at first biopsy (P = 0.027). Conclusions Weight loss in morbidly obese patients was associated with a reduction in the prevalence of hepatic fibrosis.

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Crossref · 10.1007/s11695-011-0559-y

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Research works printed but not linked: 2

  1. Oliveira CPMS, Couto CA. Doença hepática gordurosa não alcoólica e esteato-hepatite não alcoólica. In: Mattos, A.A., Dantas-Corrêa, E.B.(eds.) Tratado de hepatologia. 2010; Editora Rubio: Rio de Janeiro.
  2. Mello ES, Alves VAF. Atlas de patologia hepática. São Paulo: Editora Manole; 2010.

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Metadata

Authors
Moretto, M., Kupski, C., da Silva, V. D., Padoin, A. V., & Mottin, C. C.
Affiliations
Hospital São Lucas da PUCRS (BR)
Corresponding author
Moretto, Myriam
ORCID
Venue
Obesity Surgery
Publisher
Springer Science and Business Media LLC
Published
2011-11-23
Volume
22
Issue
7
Pages
1044-1049
ISSN
  • 0960-8923 (ISSN-L)
  • 1708-0428
DOI
10.1007/s11695-011-0559-y
OpenAlex
W2055446509
Cited by
110
References
22
Citations by year
2026: 1 · 2025: 3 · 2024: 5 · 2023: 4 · 2022: 5 · 2021: 9 · 2020: 11 · 2019: 4 · 2018: 5 · 2017: 13 · 2016: 11 · 2015: 15 · 2014: 9 · 2013: 13 · 2012: 2
FWCI
5.75
Type
journal article
Language
en
Open access
Licence
Locations
  • Obesity Surgery (publishedVersion)
  • PubMed (publishedVersion)
  • LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
  • PUCRS Repository (Pontifical Catholic University of Rio Grande do Sul) (submittedVersion, cc-by-nc-sa)
Topics
  • Health Sciences › Medicine › Hepatology › Liver Disease Diagnosis and Treatment
  • Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
  • Health Sciences › Medicine › Hepatology › Liver physiology and pathology
Keywords
bariatric surgery, liver fibrosis
MeSH terms
Adult, Fatty Liver, Female, Humans, Liver, Liver Cirrhosis, Male, Obesity, Morbid, Retrospective Studies, Gastric Bypass, Weight Loss, Prevalence, Treatment Outcome, Non-alcoholic Fatty Liver Disease

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