The Effect of Helicobacter pylori on Postoperative Outcomes in Patients Undergoing Bariatric Surgery: a Systematic Review and Meta-analysis
Abstract
Helicobacter pylori (HP) occurs in 50% of people worldwide with higher rates reported in the bariatric population. HP has been associated with adverse outcomes following bariatric surgery; however, its true impact has not yet been defined. We aimed to systematically review the effect of HP on bariatric surgery outcomes. A comprehensive literature review was conducted yielding seven studies with 255,435 patients. Meta-analysis found comparable rates of bleeding, leak, hospital length of stay, and weight loss between HP-positive and HP-negative patients. HP was, however, found to be the largest independent predictor of marginal ulceration in those undergoing RYGB, with a tenfold increase versus HP-negative patients. Overall, HP is associated with increased marginal ulceration rates, but has little impact on other bariatric surgery outcomes.
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Another meta-analysis, yielding seven studies with 255,435 patients, found similar results on H. pylori status and postoperative outcomes.
“Another meta-analysis, yielding seven studies with 255,435 patients, found similar results [38].”
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- Authors
- Mocanu, V., Dang, J. T., Switzer, N., Skubleny, D., Shi, X., de Gara, C., Birch, D. W., & Karmali, S.
- Affiliations
- University of Alberta (CA)
- Royal Alexandra Hospital (CA)
- Corresponding author
- Mocanu, Valentin
- ORCID
- Venue
- Obesity Surgery
- Published
- 2017-11-21
- Volume
- 28
- Issue
- 2
- Pages
- 567-573
- ISSN
- 0960-8923 (ISSN-L)
- 1708-0428
- OpenAlex
- W2768315313
- Cited by
- 44
- References
- 33
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 10 · 2023: 6 · 2022: 6 · 2021: 4 · 2020: 9 · 2019: 3 · 2018: 2
- FWCI
- 0.81
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Obesity Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Health Sciences › Medicine › Surgery › Helicobacter pylori-related gastroenterology studies
- Health Sciences › Medicine › Surgery › Minimally Invasive Surgical Techniques
- Keywords
- Helicobacter pylori, bariatric surgery
- MeSH terms
- Humans, Obesity, Morbid, Postoperative Period, Retrospective Studies, Weight Loss, Helicobacter pylori, Helicobacter Infections, Treatment Outcome, Bariatric Surgery
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