The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
Perioperative circulatory support for lung transplantation
Open accessAbstract
Objective Extracorporeal membrane oxygenation (ECMO) has recently replaced cardiopulmonary bypass (CPB) as the preferred option for providing circulatory support during lung transplantation. This review aimed to summarize the previous data and to address the relative use of ECMO and CPB during lung transplantation.Methods The database was searched in PubMed (Medline) using the following keywords: lung transplantation, extracorporeal membrane oxygenation, and cardiopulmonary bypass, for all relevant reports which were written in English and were published between 2000 and 2020.Review Several reports have revealed that intraoperative use of ECMO is associated with lower blood product transfusion requirements, shorter ventilator support, and shorter length of hospital stay. During recent years, preoperative ECMO has also been used with favorable outcomes as a bridge to lung transplantation in critically ill patients.Conclusions The use of ECMO during lung transplantation seems to reduce postoperative complications and improve short-term outcomes, relative to CPB. However, additional data should be collected through large multicenter randomized controlled trials. Furthermore, preoperative ECMO as a bridge to lung transplantation appears to provide favorable outcomes, although additional data are also needed from experienced transplant centers.
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Use of VA ECMO may increase the risk of bleeding complications due to cannulation, hemodilution, external circulation, and anticoagulation that are absent with off-pump support.
“Use of VA ECMO may also increase the risk of bleeding complications due to the combination of cannulation, hemodilution, external circulation, and anticoagulation that is absent with off-pump support.3,28”
From Textbook outcome in lung transplantation: Planned venoarterial extracorporeal membrane oxygenation versus off-pump support for patients without pulmonary hypertension (2022) · cites this paper as [28]
In the V-V versus V-A ECMO section (page not provided), the review reports bleeding at peripheral cannulation sites. The Comparison with off-pump section and Table 1 (pages not provided) associate off-pump support with less bleeding and no anticoagulation, while ECMO generally uses heparin. The copy does not identify hemodilution as a cause of VA ECMO bleeding, and its discussion of circuit-related bleeding concerns cardiopulmonary bypass rather than ECMO. (LLM, conf=0.85)
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Clinical risk factors for primary graft dysfunction after lung transplantation
Diamond, J. M., Lee, J. C., Kawut, S. M., Shah, R. J., Localio, A. R., Bellamy, S. L., Lederer, D. J., Cantu, E., Kohl, B. A., Lama, V. N., et al. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201210-1865oc · Cited by 687
Extracorporeal Membrane Oxygenation in Awake Patients as Bridge to Lung Transplantation
Fuehner, T., Kuehn, C., Hadem, J., Wiesner, O., Gottlieb, J., Tudorache, I., Olsson, K. M., Greer, M., Sommer, W., Welte, T., et al. (2012) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201109-1599oc · Cited by 596
Machuca, T., Collaud, S., Mercier, O. M., Cheung, M., Cunningham, V., Kim, S. J., Azad, S., Singer, L. G., Yasufuku, K., de Perrot, M. E., et al. (2014) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2014.11.039 · Cited by 253
Institutional experience with extracorporeal membrane oxygenation in lung transplantation☆
Aigner, C., Wisser, W., Taghavi, S., Láng, G., Jaksch, P., Czyżewski, D., & Klepetko, W. (2007) · European Journal of Cardio-Thoracic Surgery · doi:10.1016/j.ejcts.2006.11.049 · Cited by 237
Ius, F., Kuehn, C., Tudorache, I., Sommer, W., Avsar, M., Boethig, D., Fuehner, T., Gottlieb, J., Hoeper, M. M., Haverich, A., et al. (2012) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2012.07.095 · Cited by 226
Turner, D. A., Cheifetz, I. M., Rehder, K. J., et al. (2011) · Critical Care Medicine · doi:10.1097/ccm.0b013e3182282bbe · Cited by 205
Active Rehabilitation During Extracorporeal Membrane Oxygenation as a Bridge to Lung Transplantation
Rehder, K. J., Turner, D. A., Hartwig, M. G., Williford, W. L., Bonadonna, D. K., Walczak, R., Davis, R. D., Zaas, D., & Cheifetz, I. M. (2013) · Respiratory Care · doi:10.4187/respcare.02155 · Cited by 195
Bermudez, C. A., Shiose, A., Esper, S. A., Shigemura, N., D’Cunha, J., Bhama, J. K., Richards, T. J., Arlia, P., Crespo, M. M., & Pilewski, J. M. (2014) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2014.06.072 · Cited by 186
Biscotti, M., Yang, J. A., Sonett, J. R., & Bacchetta, M. D. (2014) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2014.07.061 · Cited by 181
Hoetzenecker, K., Donahoe, L., Yeung, J. C., Azad, S., Fan, E., Ferguson, N. D., Del Sorbo, L., de Perrot, M., Pierre, A., Yasufuku, K., et al. (2018) · The Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2017.09.161 · Cited by 164
Abrams, D. C., BRENNER, K. R., Burkart, K. M., Agerstrand, C. L., Thomashow, B. M., Bacchetta, M. D., & Brodie, D. (2013) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201301-021oc · Cited by 160
Clinical Risk Factors for Primary Graft Dysfunction after Lung Transplantation
Diamond, J. M., Lee, J. C., Kawut, S. M., Shah, R., Localio, A. R., Bellamy, S. L., Cantu, E., Lederer, D. J., Kohl, B., Lama, V. N., et al. (2013) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2013.01.911 · Cited by 157
Hoetzenecker, K., Benazzo, A., Stork, T., Sinn, K., Schwarz, S., Schweiger, T., Klepetko, W., Kifjak, D., Baron, D. M., Hager, H., et al. (2020) · The Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2019.10.155 · Cited by 157
Organ Allocation Waiting Time During Extracorporeal Bridge to Lung Transplant Affects Outcomes
Crotti, S., Iotti, G. A., Lissoni, A., Belliato, M., Zanierato, M., Chierichetti, M., Meo, G. D., Meloni, F., Pappalettera, M., Nosotti, M., et al. (2013) · CHEST Journal · doi:10.1378/chest.12-1141 · Cited by 128
Extracorporeal life support as bridge to lung transplantation: a systematic review
Chiumello, D., Coppola, S., Froio, S., Colombo, A., & Sorbo, L. D. (2015) · Critical Care · doi:10.1186/s13054-014-0686-7 · Cited by 122
Ius, F., Sommer, W., Tudorache, I., Avsar, M., Siemeni, T., Salman, J., Molitoris, U., Gras, C., Juettner, B., Puntigam, J., et al. (2016) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2015.08.016 · Cited by 115
Magouliotis, D. E., Tasiopoulou, V. S., Svokos, A. A., Svokos, K. A., & Zacharoulis, D. (2017) · General Thoracic and Cardiovascular Surgery · doi:10.1007/s11748-017-0836-3 · Cited by 101
Bittner, H. B., Binner, C., Lehmann, S., Kuntze, T., Rastan, A. J., & Mohr, F. W. (2007) · European Journal of Cardio-Thoracic Surgery · doi:10.1016/j.ejcts.2006.11.050 · Cited by 96
Low-dose heparin during extracorporeal membrane oxygenation treatment in adults
Yeo, H. J., Kim, D. H., Jeon, D., Kim, Y. S., & Cho, W. H. (2015) · Intensive Care Medicine · doi:10.1007/s00134-015-4015-7 · Cited by 79
The Munich Lung Transplant Group: Intraoperative Extracorporeal Circulation in Lung Transplantation
Winter, H., Müller, H., Meiser, B., et al. (2015) · The Thoracic and Cardiovascular Surgeon · doi:10.1055/s-0035-1556873 · Cited by 72
Pro: Lung transplantation should be routinely performed with cardiopulmonary bypass
Marczin, N., Royston, D., & Yacoub, M. H. (2000) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/jcan.2000.18592 · Cited by 71
Con: Lung transplantation should not be routinely performed with cardiopulmonary bypass
McRae, K. M. (2000) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/jcan.2000.18601 · Cited by 69
Vascular access for extracorporeal life support: tips and tricks
Reeb, J., Olland, A., Renaud, S., Lejay, A., Santelmo, N., Massard, G., & Falcoz, P. (2016) · Journal of Thoracic Disease · doi:10.21037/jtd.2016.04.42 · Cited by 66
Extracorporeal Circulation During Lung Transplantation Procedures: A Meta-Analysis
Hoechter, D. J., Shen, Y. F., Kammerer, T., Guenther, S. P. W., Weig, T. G., Schramm, R., Hagl, C. M., Born, F., Meiser, B., Preißler, G., et al. (2017) · ASAIO Journal · doi:10.1097/mat.0000000000000549 · Cited by 61
Bridging to lung transplantation with extracorporeal circulatory support: when or when not?
Loor, G., Simpson, L., & Parulekar, A. D. (2017) · Journal of Thoracic Disease · doi:10.21037/jtd.2017.08.117 · Cited by 56
Hashimoto, K., Höetzenecker, K., Yeung, J. C., Jeagal, L., Donahoe, L. L., Pierre, A. F., de Perrot, M. E., Yasufuku, K., Waddell, T. K., Keshavjee, S. H., et al. (2018) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2018.07.003 · Cited by 56
Ko, W., Chen, Y., & Lee, Y. (2001) · Artificial Organs · doi:10.1046/j.1525-1594.2001.025008607.x · Cited by 54
Gratz, J., Pausch, A., Schaden, E., Baierl, A., Jaksch, P., Erhart, F., Höetzenecker, K., & Wiegele, M. (2020) · Artificial Organs · doi:10.1111/aor.13642 · Cited by 48
Ius, F., Aburahma, K., Boethig, D., Salman, J., Sommer, W., Draeger, H., Poyanmehr, R., Avsar, M., Siemeni, T., Bobylev, D., et al. (2020) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2020.04.020 · Cited by 47
Lung Transplantation Using a Hybrid Extracorporeal Membrane Oxygenation Circuit
Thomas, M., Martin, A. K., Allen, W. L., Makey, I. A., Renew, J. R., Rodrigues, E. S., Mordecai, M., Brown, T. E., Foeks, J. J., Johnson, J. L., et al. (2020) · ASAIO Journal · doi:10.1097/mat.0000000000001157 · Cited by 27
How to minimise ventilator-induced lung injury in transplanted lungs
Soluri-Martins, A., Sutherasan, Y., Silva, P. L., et al. (2015) · European Journal of Anaesthesiology · doi:10.1097/eja.0000000000000291 · Cited by 18
Diaz‐Guzman, E., Sharma, N., Wille, K. M., & Hoopes, C. W. (2016) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2016.05.016 · Cited by 14
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Halpern, S. E., Wright, M. C., Madsen, G., Chow, B., Harris, C. S., Haney, J. C., Klapper, J. A., Bottiger, B. A., & Hartwig, M. G. (2022) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2022.07.015 · Cited by 22
Metadata
- Authors
- Ohsumi, A., & Date, H.
- Affiliations
- Kyoto University Hospital (JP)
- Corresponding author
- Ohsumi, Akihiro
- Venue
- General Thoracic and Cardiovascular Surgery
- Published
- 2021-03-05
- Volume
- 69
- Issue
- 4
- Pages
- 631-637
- ISSN
- 1863-6705 (ISSN-L)
- 1863-6713
- PMC
- PMC7934122
- OpenAlex
- W3133591539
- Cited by
- 27
- References
- 32
- Citations by year
- 2026: 1 · 2025: 5 · 2024: 11 · 2023: 4 · 2022: 5 · 2021: 1
- FWCI
- 1.26
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- General Thoracic and Cardiovascular Surgery (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Transplantation: Methods and Outcomes
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Mechanical Circulatory Support Devices
- Health Sciences › Medicine › Surgery › Cardiac and Coronary Surgery Techniques
- Keywords
- lung transplantation, extracorporeal membrane oxygenation, cardiopulmonary bypass, blood product transfusion, length of hospital stay, postoperative complications
- MeSH terms
- Cardiopulmonary Bypass, Humans, Retrospective Studies, Extracorporeal Membrane Oxygenation, Lung Transplantation, Treatment Outcome
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