Predicting and preventing acute care re-utilization by patients with diabetes
Open accessAbstract
Purpose of review Acute care re-utilization, i.e., hospital readmission and post-discharge Emergency Department (ED) use, is a significant driver of healthcare costs and a marker for healthcare quality. Diabetes is a major contributor to acute care re-utilization and associated costs. The goals of this paper are to (1) review the epidemiology of readmissions among patients with diabetes, (2) describe models that predict readmission risk, and (3) address various strategies for reducing the risk of acute care re-utilization. Recent findings Hospital readmissions and ED visits by diabetes patients are common and costly. Major risk factors for readmission include sociodemographics, comorbidities, insulin use, hospital length of stay (LOS), and history of readmissions, most of which are non-modifiable. Several models for predicting the risk of readmission among diabetes patients have been developed, two of which have reasonable accuracy in external validation. In retrospective studies and mostly small randomized controlled trials (RCTs), interventions such as inpatient diabetes education, inpatient diabetes management services, transition of care support, and outpatient follow-up are generally associated with a reduction in the risk of acute care re-utilization. Data on readmission risk and readmission risk reduction interventions are limited or lacking among patients with diabetes hospitalized for COVID-19. The evidence supporting post-discharge follow-up by telephone is equivocal and also limited. Acute care re-utilization of patients with diabetes presents an important opportunity to improve healthcare quality and reduce costs. Currently available predictive models are useful for identifying higher risk patients but could be improved. Machine learning models, which are becoming more common, have the potential to generate more accurate acute care re-utilization risk predictions. Tools embedded in electronic health record systems are needed to translate readmission risk prediction models into clinical practice. Several risk reduction interventions hold promise but require testing in multi-site RCTs to prove their generalizability, scalability, and effectiveness.
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Past ED visit frequency emerged as the strongest predictor, consistent with literature on recurrent acute care utilization and likely reflecting underlying health instability, insufficient outpatient follow-up, and barriers to primary care access.
“Past ED visit frequency emerged as the strongest predictor, consistent with literature on recurrent acute care utilization and likely reflecting underlying health instability, insufficient outpatient follow-up, and barriers to primary care access [2,9].”
From Machine learning-driven risk prediction for post-hospitalization diabetes case management: Integrating clinical and social determinants of health (2026) · cites this paper as [9]
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- Authors
- Rubin, D. J., & Shah, A. A.
- Affiliations
- Temple University (US)
- Corresponding author
- Rubin, Daniel J.
- Venue
- Current Diabetes Reports
- Published
- 2021-09
- Volume
- 21
- Issue
- 9
- Pages
- 34-34
- ISSN
- 1534-4827 (ISSN-L)
- 1539-0829
- PMC
- PMC8418292
- OpenAlex
- W3198048275
- Cited by
- 44
- References
- 64
- Citations by year
- 2026: 11 · 2025: 8 · 2024: 8 · 2023: 6 · 2022: 10 · 2021: 1
- FWCI
- 0.96
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Current Diabetes Reports (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (R01DK122073)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Health Sciences › Medicine › Epidemiology › Chronic Disease Management Strategies
- Keywords
- diabetes mellitus, hospital readmission, emergency department utilization, readmission prediction, risk factors, care transitions, post-discharge follow-up, telephone follow-up, COVID-19 pandemic, machine learning, electronic health records, health care costs, quality of care
- MeSH terms
- COVID-19, SARS-CoV-2, Diabetes Mellitus, Humans, Length of Stay, Patient Discharge, Patient Readmission, Retrospective Studies
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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