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Cited by 180

The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.

Genetics of Post-Traumatic Stress Disorder: Review and Recommendations for Genome-Wide Association Studies

Open access
Cornelis, Marilyn C., Nugent, Nicole R., Amstadter, Ananda B., Koenen, Karestan C.·2010·Current Psychiatry Reports
DOI 10.1007/s11920-010-0126-6
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Abstract

Post-traumatic stress disorder (PTSD) is a prevalent, disabling anxiety disorder that constitutes a major health care burden. Despite evidence supporting a genetic predisposition to PTSD, the precise genetic loci remain unclear. Herein we review the current state and limitations of genetic research on PTSD. Although recent years have seen an exponential increase in the number of studies examining the influence of candidate genes on PTSD diagnosis and symptomatology, most studies have been characterized by relatively low rates of PTSD, with apparent inconsistencies in gene associations linked to marked differences in methodology. We further discuss how current advances in the genetics field can be applied to studies of PTSD, emphasizing the need to adapt a genome-wide approach that facilitates discovery rather than hypothesis testing. Genome-wide association studies offer the best opportunity to identify novel “true” risk variants for the disorder that in turn has the potential to inform our understanding of PTSD etiology.

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Metadata

Authors
Cornelis, M. C., Nugent, N. R., Amstadter, A. B., & Koenen, K. C.
Venue
Current Psychiatry Reports
Publisher
Springer Science and Business Media LLC
Published
2010-06-12
Volume
12
Issue
4
Pages
313-326
ISSN
  • 1523-3812 (ISSN-L)
  • 1535-1645
DOI
10.1007/s11920-010-0126-6
OpenAlex
W2064874019
Cited by
180
References
17
FWCI
17.96
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Genetics of Post-Traumatic Stress Disorder: Review and Recommendations for Genome-Wide Association Studies. https://app.cochat.ai/papers/10.1007/s11920-010-0126-6
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Cornelis, M. C., Nugent, N. R., Amstadter, A. B., & Koenen, K. C. (2010). Genetics of Post-Traumatic Stress Disorder: Review and Recommendations for Genome-Wide Association Studies. Current Psychiatry Reports. https://doi.org/10.1007/s11920-010-0126-6

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.