Cited by 214Attention Deficit Hyperactivity DisorderSubstance Abuse Treatment and OutcomesOpioid Use Disorder Treatment

The DOI matches its Crossref record; 95 of the 95 references it cites were found in a registry or an index.

The Complicated Relationship Between Attention Deficit/Hyperactivity Disorder and Substance Use Disorders

Open access
Zulauf, Courtney A., Sprich, Susan E., Safren, Steven A., Wilens, Timothy E.·2014·Current Psychiatry Reports

Abstract

Adolescents and young adults with substance use disorders (SUD) and attention deficit/hyperactivity disorder (ADHD) are increasingly presenting in clinical practice. The overlap and role of treatment for these co-occurring disorders remains unclear. A review of the literature was conducted to highlight and update recent evidence on the overlap of ADHD and SUD, the role of ADHD medication on later SUD, and the treatment of ADHD and SUD in adolescents and young adults. Recent work continues to highlight the high risk for comorbid ADHD in patients with SUD; and conversely, the high risk for SUD developing in ADHD across the lifespan, particularly in the context of comorbid conduct disorder. Although the data remains discordant, it appears that ADHD pharmacotherapy does not increase the risk for SUD. Medication treatment alone does not appear to be particularly effective in treating SUD in currently active substance abusing individuals with ADHD. Structured therapies may be effective in treating adolescents and young adults with ADHD and SUD. Further controlled trials evaluating the sequence and effect of structured psychotherapies and/or ADHD pharmacotherapy on SUD relapse in these groups are warranted.

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  1. Katusic SK et al. Substance abuse among ADHD cases: a population-based birth cohort study. Seattle: Pediatric Academic Society; 2003.

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Metadata

Authors
Zulauf, C. A., Sprich, S. E., Safren, S. A., & Wilens, T. E.
Affiliations
Massachusetts General Hospital (US)
Corresponding author
Wilens, Timothy E.
Venue
Current Psychiatry Reports
Published
2014-02-15
Volume
16
Issue
3
Pages
436-436
ISSN
  • 1523-3812 (ISSN-L)
  • 1535-1645
OpenAlex
W2025736977
Cited by
214
References
94
Citations by year
2026: 9 · 2025: 27 · 2024: 24 · 2023: 19 · 2022: 15 · 2021: 13 · 2020: 42 · 2019: 13 · 2018: 14 · 2017: 16 · 2016: 13 · 2015: 5 · 2014: 4
FWCI
1.75
Type
journal article
Language
en
Open access
Locations
  • Current Psychiatry Reports (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institute of Mental Health (K24MH094214)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
Keywords
attention deficit hyperactivity disorder, substance use disorders, comorbidities, adolescents, young adults, ADHD medication, conduct disorder, psychotherapy, relapse prevention
MeSH terms
Adolescent, Antidepressive Agents, Attention Deficit Disorder with Hyperactivity, Central Nervous System Agents, Clinical Trials as Topic, Humans, Psychotherapy, Risk Factors, Diagnosis, Dual (Psychiatry), Adrenergic Uptake Inhibitors, Substance-Related Disorders, Young Adult

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