The DOI matches its Crossref record; 65 of the 65 references it cites were found in a registry or an index.
The effect of iron depletion on chronic hepatitis C virus infection
Open accessAbstract
Increasing evidence exists that iron overload, a common finding in chronic hepatitis C virus (HCV) infection, plays an important role in the pathophysiology of this disease. The mechanisms by which iron excess induces liver damage along with the benefit of iron depletion via phlebotomy on biochemical and histological outcomes in patients with chronic HCV infection have been discussed in this review. Finally, we focus on the effect of iron reduction on the rate of response to interferon antiviral therapy.
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“Franchini et al.,(2008) reported that chronic HCV infection is the main cause of hyperferritinemia.”
From Iron, Oxidative Stress and Health (2012) · cites this paper as Franchini et al.,(2008)
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Cites
Lauer, G. M., & Walker, B. D. (2001) · New England Journal of Medicine · doi:10.1056/nejm200107053450107 · Cited by 3,033
Jiang, Z., Zhang, Z., Wang, Z., Zhang, G., Hu, K., He, B., & Wang, S. (2011) · Hepatogastroenterology · doi:10.5754/hge11054 · Cited by 558
Measurements of iron status in patients with chronic hepatitis
Bisceglie, A. M. D., Axiotis, C. A., Hoofnagle, J. H., & Bacon, B. R. (1992) · Gastroenterology · doi:10.1016/0016-5085(92)90339-z · Cited by 388
Iron and Chronic Viral Hepatitis
Bonkovsky, H. L., Banner, B. F., & Rothman, A. L. (1997) · Hepatology · doi:10.1002/hep.510250345 · Cited by 329
Nieto, N., Friedman, S. L., & Cederbaum, A. I. (2002) · Hepatology · doi:10.1053/jhep.2002.30362 · Cited by 264
Olynyk, J. K., Reddy, K. R., Bisceglie, A. M. D., Jeffers, L. J., Parker, T., Radick, J. L., Schiff, E. R., & Bacon, B. R. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90209-0 · Cited by 252
Hayashi, H., Takikawa, T., Nishimura, N., Yano, M., Isomura, T., & Sakamoto, N. (1994) · PubMed · Cited by 226
Hepatotoxicity of Iron Overload: Mechanisms of Iron-Induced Hepatic Fibrogenesis
Ramm, G. A., & Ruddell, R. G. (2005) · Seminars in Liver Disease · doi:10.1055/s-2005-923315 · Cited by 221
Kato, J., Kobune, M., Nakamura, T., Kuroiwa, G., Takada, K., Takimoto, R., Sato, Y., Fujikawa, K., Takahashi, M., Takayama, T., et al. (2001) · PubMed · Cited by 218
Response to interferon α therapy is influenced by the iron content of the liver
Thiel, D. H. V., Friedlander, L., FAGIUOLI, S., Wright, H. I., Irish, W. D., & Gavaler, J. S. (1994) · Journal of Hepatology · doi:10.1016/s0168-8278(94)80017-0 · Cited by 208
Cited by
Sorted by citations
Bacon, B. R., Adams, P. C., Kowdley, K. V., Powell, L. W., & Tavill, A. S. (2011) · Hepatology · doi:10.1002/hep.24330 · Cited by 737
Kell, D. B. (2010) · Archives of Toxicology · doi:10.1007/s00204-010-0577-x · Cited by 361
Quantification of liver iron with MRI: State of the art and remaining challenges
Hernando, D., Levin, Y. S., Sirlin, C. B., & Reeder, S. B. (2014) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.24584 · Cited by 280
Powell, L. W., Seckington, R. C., & Deugnier, Y. (2016) · The Lancet · doi:10.1016/s0140-6736(15)01315-x · Cited by 266
Review article: the iron overload syndromes
Siddique, A., & Kowdley, K. V. (2012) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2012.05051.x · Cited by 162
Metadata
- Authors
- Franchini, M., Targher, G., Capra, F., Montagnana, M., & Lippi, G.
- Affiliations
- Azienda Ospedaliera Universitaria Integrata Verona (IT)
- University of Verona (IT)
- Corresponding author
- Franchini, Massimo
- Venue
- Hepatology International
- Published
- 2008-05-08
- Volume
- 2
- Issue
- 3
- Pages
- 335-340
- ISSN
- 1936-0533 (ISSN-L)
- 1936-0541
- PMC
- PMC2716881
- OpenAlex
- W1964002000
- Cited by
- 58
- References
- 65
- Citations by year
- 2026: 1 · 2023: 1 · 2022: 3 · 2021: 4 · 2020: 1 · 2019: 3 · 2018: 6 · 2017: 4 · 2016: 1 · 2015: 2 · 2014: 9 · 2013: 4 · 2012: 4
- FWCI
- 3.69
- Type
- journal article
- Language
- en
- Update notices
- erratum (2008-08-12)
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc
- Locations
- Hepatology International (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Hepatology › Hepatitis C virus research
- Health Sciences › Medicine › Hematology › Iron Metabolism and Disorders
- Health Sciences › Medicine › Hepatology › Liver Disease Diagnosis and Treatment
- Keywords
- iron depletion, chronic hepatitis C, iron overload, phlebotomy, interferon therapy response, liver injury
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