CoChat
Sign Up
Cited by 12Cancer survivorship and careNursing care and researchAttachment and Relationship Dynamics

Patient-caregiver relationship in cancer fatigue and distress. A dyadic approach

Open access
Taurisano, Paolo, De Feudis, Rossana L., Graziano, Giusi, Marzano, Nicola, Curci, Antonietta, Fidanzio, Antonella, Annunziata, Maria Antonietta, Antinone, Valeria +13 more·2023·Current Psychology
DOI 10.1007/s12144-022-03860-y
Open this paper in CoChat — free accountOpen PDF

Abstract

It has been shown that a reciprocal relationship between cancer patients and their family caregivers positively decreases distress in both. In this context we tried to explore the role of relationship reciprocity in the dyad members’ symptoms of fatigue and distress (anxiety and depression). Specifically, we aimed to assess the implications of relationship reciprocity testing the link between the various measurements of patient Quality of Life (QoL) and caregiver burden and the other measures of fatigue, distress, and relationship reciprocity. Moreover we aimed to examine the inter-relatedness of patients’ and caregivers’ relationship reciprocity with their own as well as fatigue and distress of the dyads. A convenience sample of 545 adult cancer patients and their caregivers from 15 cancer centers were examined using a cross-sectional design. Participants were administered dyadic measures (fatigue, distress, relationship reciprocity) and individual measures (patients’ QoL and caregivers’ burden). Patients’ QoL and caregivers’ Burden were associated with fatigue, distress and relationship reciprocity. The Actor-Partner Interdependence Model (APIM) revealed that each person’s relationship reciprocity was associated with their own distress and fatigue (actor effects); only caregivers’ relationship reciprocity was associated with patients’ fatigue and distress (partner effects). These findings suggest that the implication of the caregiving relationship for fatigue symptoms in both - patients and caregivers - appears worth of investigation.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1007/s12144-022-03860-y

Cites

4 of 4 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 45

  1. Annunziata, M. A., Muzzatti, B., Bidoli, E., Flaiban, C., Bomben, F., Piccinin, M., Gipponi, K. M., Mariutti, G., Busato, S., & Mella, S. (2020). Hospital anxiety and depression scale (HADS) accuracy in cancer patients. Supportive Care in Cancer, 28(8), 3921-3926. https:// doi. org/ 10. 1007/ s00520-019-05244-8 · DOI
  2. Badr, H., Gupta, V., Sikora, A., & Posner, M. (2014). Psychologi- cal distress in patients and caregivers over the course of radi- otherapy for head and neck Cancer. Oral Oncology, 50(10), 1005-1011. https:// doi. org/ 10. 1016/j. oralo ncolo gy. 2014. 07. 003 · DOI
  3. Berger, A. M., Gerber, L. H., & Mayer, D. K. (2012). Cancer-related fatigue: Implications for breast cancer survivors. Cancer, 118(S8), 2261-2269. https:// doi. org/ 10. 1002/ cncr. 27475 · DOI
  4. Boszormenyi-Nagy, I. K. (2013). Between Give And Take (0 ed.). Routledge. https:// doi. org/ 10. 4324/ 97802 03776 315 · DOI
  5. Boszormenyi-Nagy, I., & Krasner, B. R. (1986). Between give and take: A clinical guide to contextual therapy. Psychology Press.
  6. Bower, J. E. (2019). The role of neuro-immune interactions in can- cer-related fatigue: Biobehavioral risk factors and mechanisms. Cancer, 125(3), 353-364. https:// doi. org/ 10. 1002/ cncr. 31790 · DOI
  7. Bower, J. E., & Lamkin, D. M. (2013). Inflammation and cancer- related fatigue: Mechanisms, contributing factors, and treatment implications. Brain, Behavior, and Immunity, 30, S48-S57. https:// doi. org/ 10. 1016/j. bbi. 2012. 06. 011 · DOI
  8. Bower, J. E., Ganz, P. A., Irwin, M. R., Kwan, L., Breen, E. C., & Cole, S. W. (2011). Inflammation and behavioral symptoms after breast Cancer treatment: Do fatigue, depression, and sleep disturbance share a common underlying mechanism? Journal of Clinical Oncology, 29(26), 3517-3522. https:// doi. org/ 10. 1200/ JCO. 2011. 36. 1154 · DOI
  9. Brown, L. F., & Kroenke, K. (2009). Cancer-related fatigue and its associations with depression and anxiety: A systematic review. Psychosomatics, 50(5), 440-447. https:// doi. org/ 10. 1016/ S0033-3182(09) 70835-7 · DOI
  10. Buunk, B. P., & Schaufeli, W. B. (1999). Reciprocity in interpersonal relationships: An evolutionary perspective on its importance for health and well-being. European Review of Social Psychology, 10(1), 259-291. https:// doi. org/ 10. 1080/ 14792 77994 30000 80 · DOI
  11. Camara, C., Caroline Vos, M., de Rooij, B. H., Pijnenborg, J. M. A., Boll, D., van de Poll-Franse, L. V., & Ezendam, N. P. M. (2019). The role of positive psychological changes in anxiety and depression of patients with ovarian tumors and their part- ners: An observational study from the population-based PRO- FILES registry. Supportive Care in Cancer, 27(2), 423-431. https:// doi. org/ 10. 1007/ s00520-018-4327-6 · DOI
  12. Clark, M. M., Atherton, P. J., Lapid, M. I., Rausch, S. M., Frost, M. H., Cheville, A. L., Hanson, J. M., Garces, Y. I., Brown, P. D., Sloan, J. A., Richardson, J. W., Piderman, K. M., & Rummans, T. A. (2014). Caregivers of patients with Cancer fatigue: A high level of symptom burden. American Journal of Hospice and Palliative Medicine®, 31(2), 121-125. https:// doi. org/ 10. 1177/ 10499 09113 479153 · DOI
  13. Cook, W. L., & Kenny, D. A. (2005). The actor-partner interdepend- ence model: A model of bidirectional effects in developmen- tal studies. International Journal of Behavioral Development, 29(2), 101-109. https:// doi. org/ 10. 1080/ 01650 25044 40004 · DOI
  14. Curci, A., & Rimé, B. (2012). The temporal evolution of social shar- ing of emotions and its consequences on emotional recovery: A longitudinal study. Emotion, 12(6), 1404-1414. https:// doi. org/ 10. 1037/ a0028 651 · DOI
  15. Dekel, R., Vilchinsky, N., Liberman, G., Leibowitz, M., Khaskia, A., & Mosseri, M. (2014). Marital satisfaction and depression among couples following men's acute coronary syndrome: Test- ing dyadic dynamics in a longitudinal design. British Journal of Health Psychology, 19(2), 347-362. https:// doi. org/ 10. 1111/ bjhp. 12042 · DOI
  16. Gaston-Johansson, F., Lachica, E. M., Fall-Dickson, J. M., & John Kennedy, M. (2004). Psychological distress, fatigue, burden of care, and quality of life in primary caregivers of patients with breast Cancer undergoing autologous bone marrow transplanta- tion. Oncology Nursing Forum, 31(6), 1161-1169. https:// doi. org/ 10. 1188/ 04. ONF. 1161-1169 · DOI
  17. Gleason, M. E. J., Iida, M., Bolger, N., & Shrout, P. E. (2003). Daily supportive equity in close relationships. Personality and Social Psychology Bulletin, 29(8), 1036-1045. https:// doi. org/ 10. 1177/ 01461 67203 253473 · DOI
  18. Grassi, L., Johansen, C., Annunziata, M. A., Capovilla, E., Costantini, A., Gritti, P., Torta, R., Bellani, M., & on behalf of the Italian Society of Psycho-Oncology Distress Thermometer Study Group. (2013). Screening for distress in cancer patients: A multicenter, nationwide study in Italy. Cancer, 119(9), 1714-1721. https:// doi. org/ 10. 1002/ cncr. 27902 · DOI
  19. Gurman, A. S., & Kniskern, D. P. (1991). Handbook of family therapy (2nd ed.).
  20. Holland, J. C. (2013). Distress screening and the integration of psycho- social care into routine oncologic care. Journal of the National Comprehensive Cancer Network, 11(5S), 687-689. https:// doi. org/ 10. 6004/ jnccn. 2013. 0202 · DOI
  21. Jacobs, J. M., Shaffer, K. M., Nipp, R. D., Fishbein, J. N., MacDonald, J., El-Jawahri, A., Pirl, W. F., Jackson, V. A., Park, E. R., Temel, J. S., & Greer, J. A. (2017). Distress is interdependent in patients and caregivers with newly diagnosed incurable cancers. Annals of Behavioral Medicine, 51(4), 519-531. https:// doi. org/ 10. 1007/ s12160-017-9875-3 · DOI
  22. Karlstedt, M., Fereshtehnejad, S.-M., Aarsland, D., & Lökk, J. (2017). Determinants of dyadic relationship and its psychosocial impact in patients with Parkinson's disease and their spouses. Parkinson's Disease, 2017, 1-9. https:// doi. org/ 10. 1155/ 2017/ 46970 52 · DOI
  23. Kayser, K., & Acquati, C. (2019). The influence of relational mutuality on dyadic coping among couples facing breast cancer. Journal of Psychosocial Oncology, 37(2), 194-212. https:// doi. org/ 10. 1080/ 07347 332. 2019. 15668 · DOI
  24. Kershaw, T., Ellis, K. R., Yoon, H., Schafenacker, A., Katapodi, M., & Northouse, L. (2015). The interdependence of advanced Can- cer patients' and their family caregivers' mental health, physical health, and self-efficacy over time. Annals of Behavioral Medi- cine, 49(6), 901-911. https:// doi. org/ 10. 1007/ s12160-015-9743-y · DOI
  25. Langenberg, S. M. C. H., van Herpen, C. M. L., van Opstal, C. C. M., Wymenga, A. N. M., van der Graaf, W. T. A., & Prins, J. B. (2019). Caregivers' burden and fatigue during and after patients' treatment with concomitant chemoradiotherapy for locally advanced head and neck cancer: A prospective, observational pilot study. Supportive Care in Cancer, 27(11), 4145-4154. https:// doi. org/ 10. 1007/ s00520-019-04700-9 · DOI
  26. Ledermann, T., & Kenny, D. A. (2015). A toolbox with programs to restructure and describe dyadic data. Journal of Social and Per- sonal Relationships, 32(8), 997-1011. https:// doi. org/ 10. 1177/ 02654 07514 555273 · DOI
  27. McPherson, C. J., Wilson, K. G., Chyurlia, L., & Leclerc, C. (2010). The balance of give and take in caregiver-partner relationships: An examination of self-perceived burden, relationship equity, and quality of life from the perspective of care recipients following stroke. Rehabilitation Psychology, 55(2), 194-203. https:// doi. org/ 10. 1037/ a0019 359 · DOI
  28. McPherson, C. J., Wilson, K. G., Chyurlia, L., & Leclerc, C. (2011). The caregiving relationship and quality of life among partners of stroke survivors: A cross-sectional study. Health and Quality of Life Outcomes, 9(1), 29. https:// doi. org/ 10. 1186/ 1477-7525-9-29 · DOI
  29. Milbury, K., Badr, H., Fossella, F., Pisters, K. M., & Carmack, C. L. (2013). Longitudinal associations between caregiver burden and patient and spouse distress in couples coping with lung cancer. Supportive Care in Cancer, 21(9), 2371-2379. https:// doi. org/ 10. 1007/ s00520-013-1795-6 · DOI
  30. Minton, O., Berger, A., Barsevick, A., Cramp, F., Goedendorp, M., Mitchell, S. A., & Stone, P. C. (2013). Cancer-related fatigue and its impact on functioning: Cancer-related fatigue. Cancer, 119, 2124-2130. https:// doi. org/ 10. 1002/ cncr. 28058 · DOI
  31. O'Higgins, C. M., Brady, B., O'Connor, B., Walsh, D., & Reilly, R. B. (2018). The pathophysiology of cancer-related fatigue: Current controversies. Supportive Care in Cancer, 26(10), 3353-3364. https:// doi. org/ 10. 1007/ s00520-018-4318-7 · DOI
  32. Peters, M. E. W. J., Goedendorp, M. M., Verhagen, S. A. H. H. V. M., Smilde, T. J., Bleijenberg, G., & van der Graaf, W. T. A. (2015). A prospective analysis on fatigue and experienced burden in infor- mal caregivers of cancer patients during cancer treatment in the palliative phase. Acta Oncologica, 54(4), 500-506. https:// doi. org/ 10. 3109/ 02841 86X. 2014. 953254 · DOI
  33. Pucciarelli, G., Buck, H. G., Barbaranelli, C., Savini, S., Simeone, S., Juarez-Vela, R., Alvaro, R., & Vellone, E. (2016). Psychometric characteristics of the mutuality scale in stroke patients and car- egivers. The Gerontologist, 56(5), e89-e98. https:// doi. org/ 10. 1093/ geront/ gnw083 R Core Team (2016). R: A Language and Environment for Statisti- cal Computing. R Foundation for Statistical Computing. https:// www.R-proje ct. org/ · DOI
  34. Regan, T. W., Lambert, S. D., Kelly, B., Falconier, M., Kissane, D., & Levesque, J. V. (2015). Couples coping with cancer: Explora- tion of theoretical frameworks from dyadic studies: Couples and cancer: Dyadic theoretical frameworks. Psycho-Oncology, 24(12), 1605-1617. https:// doi. org/ 10. 1002/ pon. 3854 · DOI
  35. Reid, C. E., Moss, S., & Hyman, G. (2005). Caregiver reciprocity: The effect of reciprocity, carer self-esteem and motivation on the experience of caregiver burden. Australian Journal of Psychol- ogy, 57(3), 186-196. https:// doi. org/ 10. 1080/ 00049 53050 01410 22 · DOI
  36. Segrin, C., Badger, T., Sieger, A., Meek, P., & Lopez, A. M. (2006). Interpersonal well-being and mental health among male partners of woman with breast cancer. Issues in Mental Health Nursing, 27(4), 371-389. https:// doi. org/ 10. 1080/ 01612 84060 05696 · DOI
  37. Segrin, C., Badger, T., Dorros, S. M., Meek, P., & Lopez, A. M. (2007). Interdependent anxiety and psychological distress in women with breast cancer and their partners. Psycho-Oncology, 16(7), 634- 643. https:// doi. org/ 10. 1002/ pon. 1111 · DOI
  38. Segrin, C., Badger, T. A., & Harrington, J. (2012). Interdependent psychological quality of life in dyads adjusting to prostate cancer. Health Psychology, 31(1), 70-79. https:// doi. org/ 10. 1037/ a0025 394 · DOI
  39. Smith, T. G., Troeschel, A. N., Castro, K. M., Arora, N. K., Stein, K., Lipscomb, J., Brawley, O. W., McCabe, R. M., Clauser, S. B., & Ward, E. (2019). Perceptions of patients with breast and Colon Cancer of the Management of Cancer-Related Pain, fatigue, and emotional distress in community oncology. Journal of Clinical Oncology, 37(19), 1666-1676. https:// doi. org/ 10. 1200/ JCO. 18. 01579 · DOI
  40. Stas, L., Kenny, D. A., Mayer, A., & Loeys, T. (2018). Giving dyadic data analysis away: A user-friendly app for actor-partner interde- pendence models. Personal Relationships, 25(1), 103-119. https:// doi. org/ 10. 1111/ pere. 12230 · DOI
  41. Streck, B. P., Wardell, D. W., LoBiondo-Wood, G., & Beauchamp, J. E. S. (2020). Interdependence of physical and psychological morbid- ity among patients with cancer and family caregivers: Review of the literature. Psycho-Oncology, 29(6), 974-989. https:// doi. org/ 10. 1002/ pon. 5382 · DOI
  42. Tan, J. Y., Molassiotis, A., Lloyd-Williams, M., & Yorke, J. (2018). Burden, emotional distress and quality of life among informal caregivers of lung cancer patients: An exploratory study. Euro- pean Journal of Cancer Care, 27(1), 1-11. https:// doi. org/ 10. 1111/ ecc. 12691 · DOI
  43. Trief, P. M., Morin, P. C., Izquierdo, R., Teresi, J., Starren, J., Shea, S., & Weinstock, R. S. (2006). Marital quality and diabetes out- comes: The IDEATel project. Families, Systems & Health, 24(3), 318-331. https:// doi. org/ 10. 1037/ 1091-7527. 24.3. 318 · DOI
  44. Ybema, J. F., Kuijer, R. G., Hagedoorn, M., & Buunk, B. P. (2002). Caregiver burnout among intimate partners of patients with a severe illness: An equity perspective. Personal Relationships, 9(1), 73-88. https:// doi. org/ 10. 1111/ 1475-6811. 00005 · DOI
  45. Zigmond, A. S., & Snaith, R. P. (1983). The hospital anxiety and depression scale. Acta Psychiatrica Scandinavica, 67(6), 361- 370. https:// doi. org/ 10. 1111/j. 1600-0447. 1983. tb097 16.x · DOI · Paper page

Cited by

Sorted by citations

Authors
Taurisano, P., De Feudis, R. L., Graziano, G., Marzano, N., Curci, A., Fidanzio, A., Annunziata, M. A., Antinone, V., Brovelli, S., Carone, M., Cavanna, L., Cormio, C., Cuomo, A., Di Mattei, V., Di Silvestre, A., Lettini, A., Petrone, A., Scriminaci, M. C., Tralongo, P., De Caro, M. F., & Lanciano, T.
Affiliations
  • University of Bari Aldo Moro (IT)
  • Istituto Tumori Bari (IT)
  • Ospedale San Paolo (IT)
  • Centro di Riferimento Oncologico (IT)
  • Azienda Ospedaliero Universitaria Maggiore della Carita (IT)
  • Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari (IT)
  • Azienda Unità Sanitaria Locale Piacenza (IT)
  • Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" (IT)
  • Centro di Riferimento Oncologico della Basilicata (IT)
  • Ospedali Riuniti di Foggia (IT)
  • Fondazione Istituto Oncologico del Mediterraneo (NO)
Corresponding author
Lanciano, Tiziana
ORCID
Venue
Current Psychology
Publisher
Springer Science and Business Media LLC
Published
2022-11-05
Volume
42
Issue
32
Pages
28167-28179
ISSN
  • 1046-1310 (ISSN-L)
  • 1936-4733
DOI
10.1007/s12144-022-03860-y
OpenAlex
W4308220554
Cited by
12
References
4
Citations by year
2026: 3 · 2025: 6 · 2024: 2 · 2023: 1
FWCI
0.94
Type
journal article
Language
en
Open access
Licence
Locations
  • Current Psychology (publishedVersion, cc-by)
  • Archivio Istituzionale della Ricerca - Università Vita-Salute San Raffaele (submittedVersion, cc-by)
  • CINECA IRIS Institutional Research Information System (University of Bari Aldo Moro) (submittedVersion, cc-by-nc-nd)
Funders
Università degli Studi di Bari Aldo Moro
Topics
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
  • Health Sciences › Health Professions › Pharmacy › Nursing care and research
  • Social Sciences › Psychology › Social Psychology › Attachment and Relationship Dynamics
Keywords
cancer-related fatigue, cancer-related distress, caregiver-patient relationship, dyadic analysis, caregiver burden, quality of life, anxiety, depression, actor-partner interdependence, cancer patients, family caregivers

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review