The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Frailty: Defining and measuring of a concept
Open accessAbstract
Older, more vulnerable individuals are increasingly often described in the literature as being frail. Because frailty is often perceived as being undesirable and associated with high health risks, it is important to establish how we can predict, recognize, and treat frailty. Frailty is predisposed by advancing age in combination with physiological deterioration, especially a loss of muscle mass and bone density. Although the symptoms of frailty are diverse, the most common symptoms are a deterioration of activities of daily living (ADL), mobility, nutritional status, cognition, and endurance. The consequences of frailty are institutionalization, morbidity, and mortality. The main determinants of frailty are limitations in ADL, weight loss, diminished mobility or patterns of activity, lowered serum cholesterol level, and sensitivity to change. There is no gold standard for the measurement of frailty, and often studies use a combination of instruments. Although a couple of multidimensional instruments have been developed to measure frailty in its totality, the reliability and validity of these instruments have yet to be established. Successful interventions against frailty include increasing muscle strength through training and individualized recommendations made on the basis of an extensive geriatric assessment.
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Cites
Frailty in Older Adults: Evidence for a Phenotype
Fried, L. P., Tangen, C. M., Walston, J., Newman, A. B., Hirsch, C., Gottdiener, J., Seeman, T., Tracy, R., Kop, W. J., Burke, G., et al. (2001) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/56.3.m146 · Cited by 24,907
A global clinical measure of fitness and frailty in elderly people
Rockwood, K. (2005) · Canadian Medical Association Journal · doi:10.1503/cmaj.050051 · Cited by 8,968
Epidemiology of Sarcopenia among the Elderly in New Mexico
Baumgartner, R. N., Koehler, K. M., Gallagher, D., Romero, L., Heymsfield, S. B., Ross, R. R., Garry, P. J., & Lindeman, R. D. (1998) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009520 · Cited by 4,004
Exercise training and nutritional supplementation for physical frailty in very elderly people
Fiatarone, M. A., O'Neill, E. F., Ryan, N. D., Clements, K. M., Solares, G. R., Nelson, M. E., Roberts, S. B., Kehayias, J. J., Lipsitz, L. A., & Evans, W. J. (1994) · New England Journal of Medicine · doi:10.1056/nejm199406233302501 · Cited by 2,857
Walston, J., Hadley, E. C., Ferrucci, L., Guralnik, J. M., Newman, A. B., Studenski, S. A., Ershler, W. B., Harris, T., & Fried, L. P. (2006) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2006.00745.x · Cited by 1,605
Old or frail: what tells us more?
Schuurmans, H., Steverink, N., Lindenberg, S., Frieswijk, N., & Slaets, J. P. J. (2004) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/59.9.m962 · Cited by 491
Leng, S., Chaves, P., Koenig, K., & Walston, J. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50315.x · Cited by 387
Jones, D., Song, X., Mitnitski, A., & Rockwood, K. (2005) · Aging Clinical and Experimental Research · doi:10.1007/bf03327413 · Cited by 267
Miles, T. P., Palmer, R. F., Espino, D. V., Mouton, C. P., Lichtenstein, M. J., & Markides, K. S. (2001) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/56.1.m19 · Cited by 68
Cited by
Aging, frailty and age-related diseases
Fulop, T., Larbi, A., Witkowski, J. M., McElhaney, J., Loeb, M., Mitnitski, A., & Pawelec, G. (2010) · Biogerontology · doi:10.1007/s10522-010-9287-2 · Cited by 649
Romero-Ortuno, R., Walsh, C. D., Lawlor, B. A., & Kenny, R. A. (2010) · BMC Geriatrics · doi:10.1186/1471-2318-10-57 · Cited by 494
Measures of frailty in population-based studies: an overview
Bouillon, K., Kivimaki, M., Hamer, M., Sabia, S., Fransson, E. I., Singh-Manoux, A., Gale, C. R., & Batty, G. D. (2013) · BMC Geriatrics · doi:10.1186/1471-2318-13-64 · Cited by 469
Immunosenescence in aging: Between immune cells depletion and cytokines up-regulation
Ventura, M. T., Casciaro, M., Gangemi, S., & Buquicchio, R. (2017) · Clinical and Molecular Allergy · doi:10.1186/s12948-017-0077-0 · Cited by 389
Peters, L. L., Boter, H., Buskens, E., & Slaets, J. P. J. (2012) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2012.04.007 · Cited by 377
Metadata
- Authors
- Pel-Littel, R. E., Schuurmans, M. J., Emmelot-Vonk, M. H., & Verhaar, H. J. J.
- Venue
- The Journal of nutrition, health and aging
- Publisher
- Elsevier BV
- Published
- 2009-04
- Volume
- 13
- Issue
- 4
- Pages
- 390-394
- ISSN
- 1279-7707 (ISSN-L)
- OpenAlex
- W2015584008
- Cited by
- 172
- References
- 9
- FWCI
- 9.40
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
