The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Frailty is associated with longer hospital stay and increased mortality in hospitalized older patients
Open accessAbstract
INTRODUCTION: With the onset of frailty, there is often a rapid, progressive, and self- perpetuating downward spiral towards death. Frailty has enormous impact on acute hospital care and has been shown to be a more effective predictor of mortality than conventional clinical measures. METHODS: Hospitalized older patients admitted in medical wards at a teaching public hospital were studied to determine the prevalence of frailty; its association with anemia, congestive heart failure, clinically active tuberculosis and cognitive impairment; as well as its impact upon short-term outcome. RESULTS: A total of 250 older hospitalized patients were included, and their frailty status was assessed using Fried's criteria. Of these, 83 (33.2%) patients were frail, with frailty found to be significantly associated with increasing age. A lower mean level of haemoglobin (p, 0.002), higher chance of congestive heart failure (p, <0.001), lower mean MMSE score (p, <0.001), was found in frail older patients. Frail subjects had a higher median hospital stay. There were total of 5 deaths, all among the frail group. CONCLUSION: Our study showed that almost a third of hospitalized older patients are frail, and have anemia, higher frequency of CHF, cognitive impairment, longer hospital stay and higher mortality.
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Cites
Frailty in Older Adults: Evidence for a Phenotype
Fried, L. P., Tangen, C. M., Walston, J., Newman, A. B., Hirsch, C., Gottdiener, J., Seeman, T., Tracy, R., Kop, W. J., Burke, G., et al. (2001) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/56.3.m146 · Cited by 24,907
Kok, J. S., Berg, I. J., & Scherder, E. J. A. (2013) · Dementia and Geriatric Cognitive Disorders Extra · doi:10.1159/000353441 · Cited by 20,589
The natural history of congestive heart failure: the Framingham study
McKee, P. A., Castelli, W. P., McNamara, P. M., & Kannel, W. B. (1971) · New England Journal of Medicine · doi:10.1056/nejm197112232852601 · Cited by 3,448
Old or frail: what tells us more?
Schuurmans, H., Steverink, N., Lindenberg, S., Frieswijk, N., & Slaets, J. P. J. (2004) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/59.9.m962 · Cited by 491
Leng, S., Chaves, P., Koenig, K., & Walston, J. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50315.x · Cited by 387
Cited by
Ligthart-Melis, G. C., Luiking, Y. C., Kakourou, A., Cederholm, T., Maier, A. B., & de van der Schueren, M. A. E. (2020) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2020.03.006 · Cited by 348
What do we know about frailty in the acute care setting? A scoping review
Theou, O., Squires, E., Mallery, K., Lee, J. S., Fay, S., Goldstein, J., Armstrong, J. J., & Rockwood, K. (2018) · BMC Geriatrics · doi:10.1186/s12877-018-0823-2 · Cited by 312
Yang, X., Lupón, J., Vidán, M. T., Ferguson, C., Gastelurrutia, P., Newton, P. J., Macdonald, P. S., Bueno, H., Bayés‐Genís, A., Woo, J., et al. (2018) · Journal of the American Heart Association · doi:10.1161/jaha.117.008251 · Cited by 292
Report: NIA Workshop on Measures of Physiologic Resiliencies in Human Aging
Hadley, E. C., Kuchel, G. A., Newman, A. B., Allore, H. G., Bartley, J. M., Bergeman, C. S., Blinov, M. L., Colon-Emeric, C. S., Dabhar, F. S., Dugan, L. L., et al. (2017) · The Journals of Gerontology: Series A · doi:10.1093/gerona/glx015 · Cited by 173
Wilson, D. M., Heron, J., & Banamwana, G. (2025) · Journal of Applied Gerontology · doi:10.1177/07334648241308726 · Cited by 5
Metadata
- Authors
- Khandelwal, D., Goel, A., Kumar, U., Gulati, V., Narang, R., & Dey, A. B.
- Venue
- The Journal of nutrition, health and aging
- Publisher
- Elsevier BV
- Published
- 2012-10
- Volume
- 16
- Issue
- 8
- Pages
- 732-735
- ISSN
- 1279-7707 (ISSN-L)
- OpenAlex
- W2044317148
- Cited by
- 200
- References
- 5
- FWCI
- 4.19
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Khandelwal, D., Goel, A., Kumar, U., Gulati, V., Narang, R., & Dey, A. B. (2012). Frailty is associated with longer hospital stay and increased mortality in hospitalized older patients. The Journal of nutrition, health and aging. https://doi.org/10.1007/s12603-012-0369-5
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
