The relationship between nutritional status, functional capacity, and health-related quality of life in older adults with type 2 diabetes: a pilot explanatory study
Open accessAbstract
OBJECTIVE: To explore the relationship between nutritional status, functional capacity and health-related quality of life (HRQoL) in older adults with type 2 diabetes (T2DM). DESIGN: Cross-sectional study. SETTING AND PARTICIPANTS: Forty two non-insulin dependent older adults from a primary care center in Seville, Spain. MEASUREMENTS: Function was assessed with a battery of standardized physical fitness tests. Nutritional status was assessed using the Mini Nutritional Assessment (MNA) and the European Quality of Life Questionnaire (EQ-5D-3L) was used to assess HRQoL. RESULTS: There was an association between MNA-nutritional status and lower body strength as assessed by the chair sit-stand test (rho= .451; p= .037) and between MNA-nutritional status and EQ-5D-3L-HRQoL (EQ-5D-3Lutility, rho= .553; p<.001 and EQ-5D-3LVAS rho= .402; p<.001). An MNA item by item correlation analysis with HRQoL and lower limb strength demonstrated that HRQoL appears to be related to functional capacity (principally lower body strength, motor agility and cardiorespiratory fitness) among participants. These results were maintained when correlations were adjusted for co-morbidity. CONCLUSION: Our results demonstrated that nutritional status is moderately associated with HRQoL and lower limb strength in patients with T2DM. Our data suggest that more emphasis should be placed on interventions to encourage a correct diet and stress the needed to improve lower body strength to reinforce better mobility in T2DM population.
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Malnutrition is associated with decreases in activities of daily living, grip strength, physical performance of lower limbs, cognition, and quality of life.
“Malnutrition is also associated with decreases in activities of daily living, grip strength, physical performance of lower limbs, cognition, and quality of life (81-83).”
From 13. Older Adults: Standards of Care in Diabetes—2025 (2025) · cites this paper as [83]
The Results (Table 3; page unavailable) associate poorer nutritional status with lower-limb strength, quality of life, and reported problems with personal care and daily tasks in older adults with type 2 diabetes. They do not show an association with grip strength, and the paper does not report a nutritional-status association with cognition. The claim also omits the study’s specific population. (LLM, conf=0.87)
Experimental — accuracy not yet measuredMalnutrition is associated with decreases in activities of daily living, grip strength, physical performance of lower limbs, cognition, and quality of life.
“Malnutrition is also associated with decreases in activities of daily living, grip strength, physical performance of lower limbs, cognition, and quality of life”
From 13. Older Adults: Standards of Care in Diabetes—2026 (2026) · cites this paper as [94]
The Results (Table 3; page unavailable) associate poorer nutritional status with lower-limb strength, personal care and daily-task difficulties, and lower health-related quality of life in older adults with type 2 diabetes. They do not establish an association with reduced grip strength: the reported handgrip correlation is .142 and is not marked significant. The paper also does not report a nutritional-status association with cognition, and its findings are limited to this study population. (LLM, conf=0.88)
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- Authors
- Alfonso-Rosa, R. M., del Pozo-Cruz, B., Del Pozo-Cruz, J., Del Pozo-Cruz, J. T., & Sañudo, B.
- Affiliations
- Universidad de Sevilla (ES)
- ORCID
- Sañudo, B.
- Venue
- The Journal of nutrition, health and aging
- Publisher
- Elsevier BV
- Published
- 2013-04
- Volume
- 17
- Issue
- 4
- Pages
- 315-321
- ISSN
- 1279-7707 (ISSN-L)
- PMC
- PMC12879692
- OpenAlex
- W2030413797
- Cited by
- 52
- References
- 4
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 5 · 2023: 1 · 2022: 8 · 2021: 4 · 2020: 4 · 2019: 3 · 2018: 4 · 2017: 4 · 2016: 3 · 2015: 2 · 2014: 4 · 2013: 2
- FWCI
- 2.55
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- The journal of nutrition health & aging (publishedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (acceptedVersion, cc-by-nc-nd)
- Research Bank (Australian Catholic University) (submittedVersion)
- Deposito de Investigacion Universidad de Sevilla (University of Seville) (submittedVersion, cc-by-nc-nd)
- Topics
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
- Keywords
- type 2 diabetes, older adults, nutritional status, functional capacity, health-related quality of life, lower limb strength, physical fitness, Mini Nutritional Assessment, EQ-5D-3L, mobility (physical function), cardiorespiratory fitness, motor agility
- MeSH terms
- Aged, Cross-Sectional Studies, Diabetes Mellitus, Type 2, Female, Health Status, Humans, Male, Middle Aged, Nutritional Status, Physical Fitness, Pilot Projects, Quality of Life, Surveys and Questionnaires, Spain, Nutrition Assessment
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