Sarcopenia: its assessment, etiology, pathogenesis, consequences and future perspectives

Physical Activity and Public Health: Updated Recommendation for Adults From the American College of Sports Medicine and the American Heart Association

(2007) · Circulation · doi:10.1161/circulationaha.107.185649 · Cited by 6,545 · see citing works

Epidemiology of Sarcopenia among the Elderly in New Mexico

Baumgartner, R. N., Koehler, K. M., Gallagher, D., Romero, L., Heymsfield, S. B., Ross, R. R., Garry, P. J., & Lindeman, R. D. (1998) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009520 · Cited by 4,004 · see citing works

A C. elegans mutant that lives twice as long as wild type

Kenyon, C., Chang, J., Gensch, E., Rudner, A., & Tabtiang, R. (1993) · Nature · doi:10.1038/366461a0 · Cited by 3,387 · see citing works

Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability

Janssen, I., Heymsfield, S. B., & Ross, R. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50216.x · Cited by 3,139 · cited 4× · see citing works

Skeletal muscle mass and distribution in 468 men and women aged 18–88 yr

Janssen, I., Heymsfield, S. B., Wang, Z., & Ross, R. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.89.1.81 · Cited by 3,087 · see citing works

Physical Activity and Public Health in Older Adults

Nelson, M. E., Rejeski, W. J., Blair, S. N., Duncan, P. W., Judge, J. O., King, A. C., Macera, C. A., & Castaneda‐Sceppa, C. (2007) · Circulation · doi:10.1161/circulationaha.107.185650 · Cited by 2,991 · see citing works

Exercise training and nutritional supplementation for physical frailty in very elderly people

Fiatarone, M. A., O'Neill, E. F., Ryan, N. D., Clements, K. M., Solares, G. R., Nelson, M. E., Roberts, S. B., Kehayias, J. J., Lipsitz, L. A., & Evans, W. J. (1994) · New England Journal of Medicine · doi:10.1056/nejm199406233302501 · Cited by 2,857 · see citing works

Sarcopenia: origins and clinical relevance

Rosenberg, I. H. (1997) · The Journal of Nutrition · doi:10.1093/jn/127.5.990s · Cited by 2,399 · see citing works

Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia

Lauretani, F., Russo, C. R., Bandinelli, S., Bartali, B., Cavazzini, C., Di Iorio, A., Corsi, A. M., Rantanen, T., Guralnik, J. M., & Ferrucci, L. (2003) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00246.2003 · Cited by 1,946 · see citing works

Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link?

Yudkin, J. S., Kumari, M., Humphries, S. E., & Mohamed-Ali, V. (2000) · Atherosclerosis · doi:10.1016/s0021-9150(99)00463-3 · Cited by 1,775 · see citing works

Invited Review: Aging and sarcopenia

Doherty, T. J. (2003) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00347.2003 · Cited by 1,764 · see citing works

Strength, But Not Muscle Mass, Is Associated With Mortality in the Health, Aging and Body Composition Study Cohort

Newman, A. B., Kupelian, V., Visser, M., Simonsick, E. M., Goodpaster, B. H., Kritchevsky, S. B., Tylavsky, F. A., Rubin, S. M., Harris, T. B., & on Behalf of the Health, A. A. B. C. S. I. (2006) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/61.1.72 · Cited by 1,692 · see citing works

The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men

Bhasin, S., Storer, T. W., Berman, N., Callegari, C., Clevenger, B., Phillips, J., Bunnell, T. J., Tricker, R., Shirazi, A., & Casaburi, R. (1996) · New England Journal of Medicine · doi:10.1056/nejm199607043350101 · Cited by 1,659 · see citing works

Effects of Human Growth Hormone in Men over 60 Years Old

Rudman, D. R., Feller, A. G., Nagraj, H. S., Gergans, G. A., Lalitha, P. Y., Goldberg, A. F., Schlenker, R. A., Cohn, L., Rudman, I. W., & Mattson, D. E. (1990) · New England Journal of Medicine · doi:10.1056/nejm199007053230101 · Cited by 1,551 · see citing works

The healthcare costs of sarcopenia in the United States

Janssen, I., Shepard, D. S., Katzmarzyk, P. T., & Roubenoff, R. (2004) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2004.52014.x · Cited by 1,546 · see citing works

Fracture Prevention With Vitamin D Supplementation

Bischoff-Ferrari, H. A., Willett, W. C., Wong, J. B., Giovannucci, E. L., Dietrich, T., & Dawson‐Hughes, B. (2005) · JAMA · doi:10.1001/jama.293.18.2257 · Cited by 1,514 · see citing works

Estimation of skeletal muscle mass by bioelectrical impedance analysis

Janssen, I., Heymsfield, S. B., Baumgartner, R. N., & Ross, R. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.89.2.465 · Cited by 1,482 · see citing works

Slow and fast dietary proteins differently modulate postprandial protein accretion

Boirie, Y., Dangin, M., Gachon, P., Vasson, M.-P., Maubois, J.-L., & Beaufrère, B. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.26.14930 · Cited by 1,453 · see citing works

Muscle Mass, Muscle Strength, and Muscle Fat Infiltration as Predictors of Incident Mobility Limitations in Well-Functioning Older Persons

Visser, M., Goodpaster, B. H., Kritchevsky, S. B., Newman, A. B., Nevitt, M., Rubin, S. M., Simonsick, E. M., Harris, T. B., & Study, F. T. H. A. (2005) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/60.3.324 · Cited by 1,403 · see citing works

Myostatin Mutation Associated with Gross Muscle Hypertrophy in a Child

Schuelke, M., Wagner, K. R., Stolz, L. E., Hübner, C., Riebel, T., Kömen, W., Braun, T., Tobin, J. F., & Lee, S.-J. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa040933 · Cited by 1,399 · see citing works

Effect of Vitamin D on Falls: A Meta-analysis

Bischoff-Ferrari, H. A., Dawson-Hughes, B., Willett, W. C., Staehelin, H. B., Bazemore, M. G., Zee, R. Y., & Wong, J. B. (2004) · JAMA · doi:10.1001/jama.291.16.1999 · Cited by 1,324 · see citing works

Human aging, muscle mass, and fiber type composition.

Evans, W. J., & Lexell, J. (1995) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/50a.special_issue.11 · Cited by 1,308 · see citing works

Relationship of Interleukin-6 and Tumor Necrosis Factor-  With Muscle Mass and Muscle Strength in Elderly Men and Women: The Health ABC Study

Visser, M., Pahor, M., Taaffe, D. R., Goodpaster, B. H., Simonsick, E. M., Newman, A. B., Nevitt, M., & Harris, T. B. (2002) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/57.5.m326 · Cited by 1,294 · see citing works

Attenuation of skeletal muscle and strength in the elderly: the Health ABC Study

Goodpaster, B. H., Carlson, C. L., Visser, M., Kelley, D. E., Scherzinger, A., Harris, T. B., Stamm, E., & Newman, A. B. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.90.6.2157 · Cited by 1,226 · see citing works

Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans

Herndon, L. A., Schmeissner, P. J., Dudaronek, J. M., Brown, P. A., Listner, K. M., Sakano, Y., Paupard, M. C., Hall, D. H., & Driscoll, M. (2002) · Nature · doi:10.1038/nature01135 · Cited by 1,214 · see citing works

Dietary protein intake is associated with lean mass change in older, community-dwelling adults: the Health, Aging, and Body Composition (Health ABC) Study

Houston, D. K., Nicklas, B. J., Ding, J., Harris, T. B., Tylavsky, F. A., Newman, A. B., Lee, J. S., Sahyoun, N. R., Visser, M., & Kritchevsky, S. B. (2008) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/87.1.150 · Cited by 1,214 · see citing works

Summary comments

Rosenberg, I. H. (1989) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/50.5.1231 · Cited by 1,201 · see citing works

Skeletal Muscle Cutpoints Associated with Elevated Physical Disability Risk in Older Men and Women

Janssen, I. (2004) · American Journal of Epidemiology · doi:10.1093/aje/kwh058 · Cited by 1,190 · see citing works

Mechanisms of Muscle Wasting — The Role of the Ubiquitin–Proteasome Pathway

Mitch, W. E., & Goldberg, A. L. (1996) · New England Journal of Medicine · doi:10.1056/nejm199612193352507 · Cited by 1,163 · see citing works

Muscle strength and speed of movement in relation to age and muscle morphology

Larsson, L., Grimby, G., & Karlsson, J. (1979) · Journal of Applied Physiology · doi:10.1152/jappl.1979.46.3.451 · Cited by 1,135 · see citing works

Low Vitamin D and High Parathyroid Hormone Levels as Determinants of Loss of Muscle Strength and Muscle Mass (Sarcopenia): The Longitudinal Aging Study Amsterdam

Visser, M., Deeg, D. J. H., & Lips, P. T. A. M. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-030604 · Cited by 1,100 · see citing works

The I.A.N.A. task force on frailty assessment of older people in clinical practice

Van Kan, G. A., Rolland, Y., Bergman, H., Morley, J. E., Kritchevsky, S. B., & Vellas, B. (2008) · The Journal of nutrition, health and aging · doi:10.1007/bf02982161 · Cited by 1,099 · see citing works

Body Composition in Healthy Aging

BAUMGARTNER, R. N. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06498.x · Cited by 1,078 · see citing works

Inflammatory markers and loss of muscle mass (sarcopenia) and strength

Schaap, L. A., Pluijm, S. M. F., Deeg, D. J. H., & Visser, M. (2006) · The American Journal of Medicine · doi:10.1016/j.amjmed.2005.10.049 · Cited by 1,047 · see citing works

Designing Randomized, Controlled Trials Aimed at Preventing or Delaying Functional Decline and Disability in Frail, Older Persons: A Consensus Report

Ferrucci, L., Guralnik, J. M., Studenski, S., Fried, L. P., Cutler, G. B., Walston, J. D., & The Interventions on Frailty Working Group (2004) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2004.52174.x · Cited by 1,027 · cited 1× · see citing works

Increased mortality associated with growth hormone treatment in critically ill adults

Takala, J., Ruokonen, E., Webster, N. R., Nielsen, M. S., Zandstra, D. F., Vundelinckx, G., & Hinds, C. J. (1999) · New England Journal of Medicine · doi:10.1056/nejm199909093411102 · Cited by 1,023 · see citing works

Sarcopenia: alternative definitions and associations with lower extremity function

Newman, A. B., Kupelian, V., Visser, M., Simonsick, E., Goodpaster, B., Nevitt, M., Kritchevsky, S. B., Tylavsky, F. A., Rubin, S. M., Harris, T. B., et al. (2003) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2003.51534.x · Cited by 981 · see citing works

Appendicular skeletal muscle mass: effects of age, gender, and ethnicity

Gallagher, D., Visser, M., De Meersman, R. E., Sepúlveda, D., Baumgartner, R. N., Pierson, R. N., Harris, T., & Heymsfield, S. B. (1997) · Journal of Applied Physiology · doi:10.1152/jappl.1997.83.1.229 · Cited by 966 · see citing works

Leg extensor power and functional performance in very old men and women.

Bassey, E. J., Fiatarone, M. A., O'neill, E. F., Kelly, M., Evans, W. J., & Lipsitz, L. A. (1992) · Clinical Science · doi:10.1042/cs0820321 · Cited by 943 · see citing works

Sarcopenia

Morley, J. E., Baumgartner, R., Roubenoff, R., Mayer, J., & Nair, K. S. (2001) · Journal of Laboratory and Clinical Medicine · doi:10.1067/mlc.2001.113504 · Cited by 938 · see citing works

Sarcopenic Obesity Predicts Instrumental Activities of Daily Living Disability in the Elderly

Baumgartner, R. N., Wayne, S. J., Waters, D. L., Janssen, I., Gallagher, D., & Morley, J. E. (2004) · Obesity Research · doi:10.1038/oby.2004.250 · Cited by 937 · see citing works

Effect of 10 Days of Bed Rest on Skeletal Muscle in Healthy Older Adults

Kortebein, P., Ferrando, A., Lombeida, J., Wolfe, R., & Evans, W. J. (2007) · JAMA · doi:10.1001/jama.297.16.1772-b · Cited by 933 · see citing works

Testosterone Replacement in Older Hypogonadal Men: A 12-Month Randomized Controlled Trial

Sih, R., Morley, J. E., Kaiser, F. E., Perry, H. M., Patrick, P., & Ross, C. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.6.3988 · Cited by 920 · see citing works

INCREASED MORTALITY ASSOCIATED WITH GROWTH HORMONE TREATMENT IN CRITICALLY ILL ADULTS

Akala, J. U. T., Uokonen, E. S. R., Igel, N., Ebster, R. W., Ielsen, M. I. S. N., Andstra, D. U. F. Z., Undelinckx, G. U. V., & Inds, H. J. H. (1999) · Cited by 889 · see citing works

Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults

Volpi, E., Kobayashi, H., Sheffield-Moore, M., Mittendorfer, B., & Wolfe, R. R. (2003) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/78.2.250 · Cited by 846 · see citing works

Leg muscle mass and composition in relation to lower extremity performance in men and women aged 70 to 79: the health, aging and body composition study

Visser, M., Kritchevsky, S. B., Goodpaster, B. H., Newman, A. B., Nevitt, M., Stamm, E., & Harris, T. B. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50217.x · Cited by 845 · see citing works

Longitudinal changes in testosterone, luteinizing hormone, and follicle-stimulating hormone in healthy older men

Morley, J. E., Kaiser, F. E., Perry, H. M., Patrick, P., Morley, P. M. K., Stauber, P. M., Vellas, B., Baumgartner, R. N., & Garry, P. J. (1997) · Metabolism · doi:10.1016/s0026-0495(97)90057-3 · Cited by 830 · see citing works

Anthropometric measurement of muscle mass: revised equations for calculating bone-free arm muscle area

Heymsfield, S. B., McManus, C., Smith, J. L., Stevens, V. L., & Nixon, D. (1982) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/36.4.680 · Cited by 825 · see citing works

Alternative definitions of sarcopenia, lower extremity performance, and functional impairment with aging in older men and women

Delmonico, M. J., Harris, T. B., Lee, J., Visser, M., Nevitt, M., Kritchevsky, S. B., Tylavsky, F. A., Newman, A. B., & for the Health, A. A. B. C. S. (2007) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2007.01140.x · Cited by 819 · see citing works

Appendicular skeletal muscle mass: measurement by dual-photon absorptiometry

Heymsfield, S. B., Smith, R. C., Aulet, M., Bensen, B., Lichtman, S. W., Wang, J., & Pierson, R. (1990) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/52.2.214 · Cited by 819 · see citing works

Aging of the human neuromuscular system

Vandervoort, A. A. (2001) · Muscle & Nerve · doi:10.1002/mus.1215 · Cited by 813 · see citing works

Serum IL‐6 Level and the Development of Disability in Older Persons

Ferrucci, L., Harris, T. B., Guralnik, J. M., Tracy, R. P., Corti, M., Cohen, H. J., Penninx, B., Pahor, M., Wallace, R., & Havlik, R. J. (1999) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1999.tb01583.x · Cited by 809 · see citing works

Predictors of skeletal muscle mass in elderly men and women

Baumgartner, R. N., Waters, D. L., Gallagher, D., Morley, J. E., & Garry, P. J. (1999) · Mechanisms of Ageing and Development · doi:10.1016/s0047-6374(98)00130-4 · Cited by 809 · cited 1× · see citing works

Longitudinal changes in body composition in older men and women: role of body weight change and physical activity

Hughes, V. A., Frontera, W. R., Roubenoff, R., Evans, W. J., & Singh, M. A. F. (2002) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/76.2.473 · Cited by 804 · see citing works

Increase in bone density and lean body mass during testosterone administration in men with acquired hypogonadism.

Katznelson, L., Finkelstein, J. S., Schoenfeld, D. A., Rosenthal, D. I., Anderson, E. J., & Klibanski, A. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.81.12.8954042 · Cited by 791 · cited 1× · see citing works

Cachexia: pathophysiology and clinical relevance1,2

Morley, J. E., Thomas, D. R., & Wilson, M.-M. G. (2006) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/83.4.735 · Cited by 786 · see citing works

Changes in agonist-antagonist EMG, muscle CSA, and force during strength training in middle-aged and older people

Häkkinen, K., Kallinen, M., Izquierdo, M., Jokelainen, K., Lassila, H., Mälkiä, E., Kraemer, W. J., Newton, R. U., & Alen, M. (1998) · Journal of Applied Physiology · doi:10.1152/jappl.1998.84.4.1341 · Cited by 776 · see citing works

Effects of testosterone supplementation in the aging male

Tenover, J. S. (1992) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.75.4.1092 · Cited by 768 · see citing works

Frailty: Toward a Clinical Definition

van Kan, G. A., Rolland, Y., Morley, J. E., & Vellas, B. J. (2008) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2007.11.005 · Cited by 723 · see citing works

Effects of testosterone supplementation in the aging male.

Tenover, J. S. (1992) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.75.4.1400877 · Cited by 702 · see citing works

Sarcopenia: Current Concepts

Roubenoff, R., & HUGHES, V. A. (2000) · The Journals of Gerontology Series A · doi:10.1093/gerona/55.12.m716 · Cited by 687 · see citing works

Handgrip strength and cause-specific and total mortality in older disabled women: exploring the mechanism

Rantanen, T., Volpato, S., Luigi Ferrucci, M., Eino Heikkinen, M., Fried, L. P., & Guralnik, J. M. (2003) · Journal of the American Geriatrics Society · doi:10.1034/j.1600-0579.2003.00207.x · Cited by 661 · see citing works

IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1

Musarò, A., McCullagh, K. J. A., Naya, F. J., Olson, E. N., & Rosenthal, N. A. (1999) · Nature · doi:10.1038/23060 · Cited by 652 · see citing works

Role of muscle loss in the age-associated reduction in VO2 max

Fleg, J. L., & Lakatta, E. G. (1988) · Journal of Applied Physiology · doi:10.1152/jappl.1988.65.3.1147 · Cited by 631 · see citing works

The Role of Muscle Loss in the Age-Related Decline of Grip Strength: Cross-Sectional and Longitudinal Perspectives

Kallman, D. A., Plato, C. C., & Tobin, J. D. (1990) · Journal of Gerontology · doi:10.1093/geronj/45.3.m82 · Cited by 629 · see citing works

Epidemiology of Sarcopenia

III, L. J. M., Khosla, S., Crowson, C. S., O'Connor, M. K., O'Fallon, W. M., & Riggs, B. L. (2000) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2000.tb04719.x · Cited by 598 · see citing works

Muscle quality. I. Age-associated differences between arm and leg muscle groups

Lynch, N. A., Metter, E. J., Lindle, R. S., Fozard, J. L., Tobin, J. D., Roy, T. A., Fleg, J. L., & Hurley, B. F. (1999) · Journal of Applied Physiology · doi:10.1152/jappl.1999.86.1.188 · Cited by 596 · see citing works

Extent of motor unit activation during effort

Belanger, A. Y., & McComas, A. J. (1981) · Journal of Applied Physiology · doi:10.1152/jappl.1981.51.5.1131 · Cited by 583 · see citing works

Muscle tissue changes with aging

Volpi, E., Nazemi, R., & Fujita, S. (2004) · Current Opinion in Clinical Nutrition and Metabolic Care · doi:10.1097/01.mco.0000134362.76653.b2 · Cited by 569 · see citing works

Effect of age on <i>in vivo</i> rates of mitochondrial protein synthesis in human skeletal muscle

Rooyackers, O. E., Adey, D. B., Ades, P. A., & Nair, K. S. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.26.15364 · Cited by 564 · see citing works

Aging of human muscle: structure, function and adaptability

Porter, M. M., Vandervoort, A. A., & Lexell, J. E. (1995) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/j.1600-0838.1995.tb00026.x · Cited by 555 · see citing works

Evidence for a non-linear relationship between leg strength and gait speed

BUCHNER, D. M., LARSON, E. B., WAGNER, E. H., KOEPSELL, T. D., & DE LATEUR, B. J. (1996) · Age and Ageing · doi:10.1093/ageing/25.5.386 · Cited by 542 · see citing works

Loss of skeletal muscle mass in aging: Examining the relationship of starvation, sarcopenia and cachexia

Thomas, D. R. (2007) · Clinical Nutrition · doi:10.1016/j.clnu.2007.03.008 · Cited by 521 · see citing works

Vitamin D and muscle function

Pfeifer, M., Begerow, B., & Minne, H. W. (2002) · Osteoporosis International · doi:10.1007/s001980200012 · Cited by 521 · see citing works

Effect of Testosterone Supplementation on Functional Mobility, Cognition, and Other Parameters in Older Men: A Randomized Controlled Trial

Emmelot-Vonk, M. H., Verhaar, H. J. J., Nakhai Pour, H. R., Aleman, A., Lock, T. M. T. W., Bosch, J. L. H. R., Grobbee, D. E., & van der Schouw, Y. T. (2008) · JAMA · doi:10.1001/jama.2007.51 · Cited by 518 · see citing works

In Situ Detection of 1,25-dihydroxyvitamin D Receptor In human Skeletal Muscle Tissue

Bischoff, H. A., Borchers, M., Gudat, F. G., Dürmüller, U., Theiler, R., Stähelin, H. B., & Dick, W. (2001) · The Histochemical Journal · doi:10.1023/a:1017535728844 · Cited by 514 · see citing works

Sarcopenia, Calf Circumference, and Physical Function of Elderly Women: A Cross‐Sectional Study

Rolland, Y., Lauwers‐Cancès, V., Cournot, M., Nourhashémi, F., Reynish, W., Rivière, D., Vellas, B. J., & Grandjean, H. (2003) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2003.51362.x · Cited by 509 · see citing works

Strength and muscle quality in a well-functioning cohort of older adults: the Health, Aging and Body Composition Study

Newman, A. B., Haggerty, C. L., Goodpaster, B., Harris, T., Kritchevsky, S., Nevitt, M., Miles, T. P., Visser, M., & The Health, A. (2003) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2003.51105.x · Cited by 505 · see citing works

Aging is associated with diminished accretion of muscle proteins after the ingestion of a small bolus of essential amino acids

Katsanos, C. S., Kobayashi, H., Sheffield‐Moore, M., Aarsland, A. A., & Wolfe, R. R. (2005) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/82.5.1065 · Cited by 504 · see citing works

Histochemical and biochemical changes in human skeletal muscle with age in sedentary males, age 22–65 years

Larsson, L., Sjödin, B., & Karlsson, J. (1978) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1978.tb06187.x · Cited by 498 · see citing works

Ultrasonographic assessment of human skeletal muscle size

Reeves, N. D., Maganaris, C. N., & Narici, M. V. (2004) · European Journal of Applied Physiology · doi:10.1007/s00421-003-0961-9 · Cited by 492 · see citing works

Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts

Stump, C. S., Short, K. R., Bigelow, M. L., Schimke, J. M., & Nair, K. S. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1332551100 · Cited by 477 · see citing works

Growth Hormone Replacement in Healthy Older Men Improves Body Composition but Not Functional Ability

Papadakis, M. A., Grady, D., Black, D., Tierney, M. J., Gooding, G. A. W., Schambelan, M., & Grunfeld, C. (1996) · Annals of Internal Medicine · doi:10.7326/0003-4819-124-8-199604150-00002 · Cited by 474 · see citing works

The Response of Muscle Protein Anabolism to Combined Hyperaminoacidemia and Glucose-Induced Hyperinsulinemia Is Impaired in the Elderly¹

Volpi, E., Mittendorfer, B., Rasmussen, B. B., & Wolfe, R. R. (2000) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jcem.85.12.7021 · Cited by 464 · see citing works

Effects of Testosterone Replacement Therapy in Old Hypogonadal Males: A Preliminary Study

Morley, J. E., Perry, H. M., Kaiser, F. E., Kraenzle, D., Jensen, J., Houston, K., Mattammal, M. B., & Perry, H. M. (1993) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1993.tb02049.x · Cited by 462 · see citing works

Influence of Sarcopenia on the Development of Physical Disability: The Cardiovascular Health Study

Janssen, I. (2006) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2005.00540.x · Cited by 459 · see citing works

Physical frailty and body composition in obese elderly men and women

Villareal, D. T., Banks, M., Siener, C., Sinacore, D. R., & Klein, S. (2004) · Obesity Research · doi:10.1038/oby.2004.111 · Cited by 459 · see citing works

Skeletal muscle adaptations to endurance training in 60- to 70-yr-old men and women

Coggan, A. R., Spina, R. J., King, D. S., Rogers, M. A., Brown, M., Nemeth, P. M., & Holloszy, J. O. (1992) · Journal of Applied Physiology · doi:10.1152/jappl.1992.72.5.1780 · Cited by 457 · see citing works

Effects of transdermal testosterone on bone and muscle in older men with low bioavailable testosterone levels

Kenny, A. M., Prestwood, K. M., Gruman, C. A., Marcello, K. M., & Raisz, L. G. (2001) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/56.5.m266 · Cited by 456 · see citing works

Vitamin D deficiency, muscle function, and falls in elderly people

Janssen, H. C. J. P., Samson, M., & Verhaar, H. J. J. (2002) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/75.4.611 · Cited by 456 · see citing works

Growth Hormone and Sex Steroid Administration in Healthy Aged Women and Men: A Randomized Controlled Trial

Blackman, M. R. (2002) · JAMA · doi:10.1001/jama.288.18.2282 · Cited by 455 · see citing works

Oral amino acids stimulate muscle protein anabolism in the elderly despite higher first-pass splanchnic extraction.

Volpi, E., Mittendorfer, B., Wolf, S., & Wolfe, R. R. (1999) · American Journal of Physiology · doi:10.1152/ajpendo.1999.277.3.e513 · Cited by 449 · see citing works

Role of Vitamin D in Skeletal Muscle Function*

Boland, R. (1986) · Endocrine Reviews · doi:10.1210/edrv-7-4-434 · Cited by 436 · see citing works

Percentage of body fat and body mass index are associated with mobility limitations in people aged 70 and older from NHANES III

Davison, K. K., Ford, E. S., Cogswell, M. E., & Dietz, W. H. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50508.x · Cited by 435 · see citing works

An Evidence-Based Assessment of Federal Guidelines for Overweight and Obesity as They Apply to Elderly Persons

Heiat, A., Vaccarino, V., & Krumholz, H. M. (2001) · Archives of Internal Medicine · doi:10.1001/archinte.161.9.1194 · Cited by 434 · see citing works

Once‐Weekly Resistance Exercise Improves Muscle Strength and Neuromuscular Performance in Older Adults

Taaffe, D. R., Duret, C., Wheeler, S., & Marcus, R. (1999) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1999.tb05201.x · Cited by 426 · see citing works

Sarcopenia, obesity, and inflammation—results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors study

Cesari, M., Kritchevsky, S. B., Baumgartner, R., Atkinson, H. H., Penninx, B. W. J. H., Lenchik, L., Palla, S. L., Ambrosius, W. T., Tracy, R. P., & Pahor, M. (2005) · American Journal of Clinical Nutrition · doi:10.1093/ajcn.82.2.428 · Cited by 422 · see citing works

Monocyte Cytokine Production in an Elderly Population: Effect of Age and Inflammation

Roubenoff, R., Harris, T. B., Abad, L. W., Wilson, P. W. F., Dallal, G. E., & Dinarello, C. A. (1998) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/53a.1.m20 · Cited by 418 · see citing works

Genetic Influences on Muscle Strength, Lean Body Mass, and Bone Mineral Density: A Twin Study

Arden, N., & Spector, T. D. (1997) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1997.12.12.2076 · Cited by 414 · see citing works

Impaired anabolic response of muscle protein synthesis is associated with S6K1 dysregulation in elderly humans

Guillet, C., Prod'homme, M., Balage, M., Gachon, P., Giraudet, C., Morin, L., Grizard, J., & Boirie, Y. (2004) · The FASEB Journal · doi:10.1096/fj.03-1341fje · Cited by 412 · see citing works

Acute effects of resistance exercise on muscle protein synthesis rate in young and elderly men and women

Yarasheski, K. E., Zachwieja, J. J., & Bier, D. M. (1993) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1993.265.2.e210 · Cited by 406 · see citing works

Insulin resistance of muscle protein metabolism in aging

Rasmussen, B. B., Fujita, S., Wolfe, R. R., Mittendorfer, B., Roy, M., Rowe, V. L., & Volpi, E. (2006) · The FASEB Journal · doi:10.1096/fj.05-4607fje · Cited by 402 · see citing works

The Recommended Dietary Allowance for Protein May Not Be Adequate for Older People to Maintain Skeletal Muscle

Campbell, W. W., Trappe, T. A., Wolfe, R. R., & Evans, W. J. (2001) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/56.6.m373 · Cited by 397 · see citing works

Physical disability and muscular strength in relation to obesity and different body composition indexes in a sample of healthy elderly women

Zoico, E., Di Francesco, V, Guralnik, J. M., Mazzali, G., Bortolani, A., Guariento, S., Sergi, G., Bosello, O., & Zamboni, M. (2004) · International Journal of Obesity · doi:10.1038/sj.ijo.0802552 · Cited by 392 · see citing works

Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging

Drummond, M. J., Dreyer, H. C., Pennings, B., Fry, C. S., Dhanani, S., Dillon, E. L., Sheffield‐Moore, M., Volpi, E., & Rasmussen, B. B. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00021.2008 · Cited by 391 · see citing works

Exogenous amino acids stimulate net muscle protein synthesis in the elderly.

Volpi, E., Ferrando, A. A., Yeckel, C. W., Tipton, K. D., & Wolfe, R. R. (1998) · Journal of Clinical Investigation · doi:10.1172/jci939 · Cited by 390 · see citing works

Effects of motor unit losses on strength in older men and women

Doherty, T. J., Vandervoort, A. A., Taylor, A. W., & Brown, W. F. (1993) · Journal of Applied Physiology · doi:10.1152/jappl.1993.74.2.868 · Cited by 379 · see citing works

Angiotensin II Induces Interleukin-6 Transcription in Vascular Smooth Muscle Cells Through Pleiotropic Activation of Nuclear Factor-κB Transcription Factors

Han, Y., Runge, M. S., & Brasier, A. R. (1999) · Circulation Research · doi:10.1161/01.res.84.6.695 · Cited by 377 · see citing works

Splanchnic and whole-body leucine kinetics in young and elderly men

Boirie, Y., Gachon, P., & Beaufrère, B. (1997) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/65.2.489 · Cited by 353 · see citing works

Interventions for sarcopenia and muscle weakness in older people

Borst, S. E. (2004) · Age and Ageing · doi:10.1093/ageing/afh201 · Cited by 349 · see citing works

Skeletal muscle apoptosis, sarcopenia and frailty at old age

Marzetti, E., & Leeuwenburgh, C. (2006) · Experimental Gerontology · doi:10.1016/j.exger.2006.08.011 · Cited by 346 · see citing works

Sarcopenia, obesity, and inflammation—results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors study

Cesari, M., Kritchevsky, S. B., Baumgartner, R., et al. (2005) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/82.2.428 · Cited by 345 · see citing works

Resistance Exercise Reverses Aging in Human Skeletal Muscle

Melov, S., Tarnopolsky, M. A., Beckman, K. B., Felkey, K., & Hubbard, A. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000465 · Cited by 344 · see citing works

Oral Testosterone Supplementation Increases Muscle and Decreases Fat Mass in Healthy Elderly Males With Low-Normal Gonadal Status

Wittert, G., Chapman, I. M., Haren, M. T., Mackintosh, S. F., Coates, P. S., & Morley, J. E. (2003) · The Journals of Gerontology Series A · doi:10.1093/gerona/58.7.m618 · Cited by 344 · see citing works

Skeletal muscle lipid deposition and insulin resistance: effect of dietary fatty acids and exercise

Corcoran, M. P., Lamon-Fava, S., & Fielding, R. A. (2007) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/85.3.662 · Cited by 341 · see citing works

Relation between use of angiotensin-converting enzyme inhibitors and muscle strength and physical function in older women: an observational study

Onder, G., Penninx, B. W., Balkrishnan, R., Fried, L. P., Chaves, P. H., Williamson, J., Carter, C., Bari, M. D., Guralnik, J. M., & Pahor, M. (2002) · The Lancet · doi:10.1016/s0140-6736(02)08024-8 · Cited by 339 · see citing works

Skeletal muscle contractile and noncontractile components in young and older women and men

Kent‐Braun, J. A., Ng, A. V., & Young, K. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.88.2.662 · Cited by 338 · see citing works

Exercise: Effects on Physical Functional Performance in Independent Older Adults

Cress, M. E., Büchner, D. M., Questad, K. A., Esselman, P. C., deLateur, B. J., & Schwartz, R. S. (1999) · The Journals of Gerontology Series A · doi:10.1093/gerona/54.5.m242 · Cited by 337 · see citing works

Increased energy requirements and changes in body composition with resistance training in older adults

Campbell, W. W., Crim, M. C., Young, V. R., & Evans, W. (1994) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/60.2.167 · Cited by 330 · see citing works

High body fatness, but not low fat-free mass, predicts disability in older men and women: the Cardiovascular Health Study

Visser, M., Langlois, J. A., Guralnik, J. M., Cauley, J. A., Kronmal, R. A., Robbins, J., Williamson, J. D., & Harris, T. B. (1998) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/68.3.584 · Cited by 328 · see citing works

Trends in Waist Circumference among U.S. Adults

Ford, E. S., Mokdad, A. H., & Giles, W. H. (2003) · Obesity Research · doi:10.1038/oby.2003.168 · Cited by 327 · see citing works

Functional and Metabolic Consequences of Sarcopenia

Vandervoort, A. A., & Symons, T. B. (2001) · Canadian Journal of Applied Physiology · doi:10.1139/h01-007 · Cited by 324 · see citing works

Sarcopenia and increased adipose tissue infiltration of muscle in elderly African American women

Song, M.-Y., Ruts, E., Kim, J., Janumala, I., Heymsfield, S., & Gallagher, D. (2004) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/79.5.874 · Cited by 324 · see citing works

In Vivo Body Composition Studies

Yasumura, S., Harrison, J. E., McNeill, K. G., Woodhead, A. D., & Dilmanian, F. A. (1990) · Springer eBooks · doi:10.1007/978-1-4613-1473-8 · Cited by 317 · see citing works

Muscle strength, disability and mortality

Rantanen, T. (2003) · Scandinavian Journal of Medicine &amp; Science in Sports · doi:10.1034/j.1600-0838.2003.00298.x · Cited by 317 · cited 1× · see citing works

Associations of Body Composition with Physical Performance and Self-reported Functional Limitation in Elderly Men and Women

Sternfeld, B. (2002) · American Journal of Epidemiology · doi:10.1093/aje/kwf023 · Cited by 312 · see citing works

Influence of the Protein Digestion Rate on Protein Turnover in Young and Elderly Subjects

Dangin, M., Boirie, Y., Guillet, C., & Beaufrère, B. (2002) · The Journal of Nutrition · doi:10.1093/jn/131.10.3228s · Cited by 312 · see citing works

Catabolism of aging: is it an inflammatory process?

Roubenoff, R. (2003) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/01.mco.0000068965.34812.62 · Cited by 307 · see citing works

Obesity in the Elderly

Elia, M. (2001) · Obesity Research · doi:10.1038/oby.2001.126 · Cited by 304 · see citing works

Principles and Practice of Geriatric Medicine

(2005) · Wiley eBooks · doi:10.1002/047009057x · Cited by 303 · see citing works

Chronic inflammation and the effect of IGF-I on muscle strength and power in older persons

Barbieri, M., Ferrucci, L., Ragno, E., Corsi, A., Bandinelli, S., Bonafè, M., Olivieri, F., Giovagnetti, S., Franceschi, C., Guralnik, J. M., et al. (2003) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00319.2002 · Cited by 303 · see citing works

Insulin-like growth factor physiology and cancer risk

Pollak, M. (2000) · European Journal of Cancer · doi:10.1016/s0959-8049(00)00102-7 · Cited by 296 · see citing works

Resistance Exercise and Physical Performance in Adults Aged 60 to 83

Vincent, K. R., Braith, R. W., Feldman, R. A., Magyari, P. M., Cutler, R. B., Persin, S. A., Lennon, S. L., Gabr, A., & Lowenthal, D. T. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50267.x · Cited by 294 · see citing works

Resistance exercise acutely increases MHC and mixed muscle protein synthesis rates in 78–84 and 23–32 yr olds

Hasten, D. L., Pak-Loduca, J., Obert, K. A., & Yarasheski, K. E. (2000) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2000.278.4.e620 · Cited by 294 · see citing works

Potentially predictive and manipulable blood serum correlates of aging in the healthy human male: Progressive decreases in bioavailable testosterone, dehydroepiandrosterone sulfate, and the ratio of insulin-like growth factor 1 to growth hormone

Morley, J. E., Kaiser, F. E., Raum, W. J., Perry, H. M., Flood, J. F., Jensen, J., Silver, A. J., & Roberts, E. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.14.7537 · Cited by 289 · see citing works

Effects of Age, Gender, and Myostatin Genotype on the Hypertrophic Response to Heavy Resistance Strength Training

Ivey, F. M., Roth, S. M., Ferrell, R. E., Tracy, B. L., Lemmer, J. T., Hurlbut, D. E., Martel, G. F., Siegel, E. L., Fozard, J. L., Metter, E. J., et al. (2000) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/55.11.m641 · Cited by 288 · see citing works

Protein pulse feeding improves protein retention in elderly women

Arnal, M.-A., Mosoni, L., Boirie, Y., Houlier, M.-L., Morin, L., Verdier, E., Ritz, P., Antoine, J.-M., Prugnaud, J., Beaufrère, B., et al. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.6.1202 · Cited by 284 · see citing works

Muscle fiber‐specific apoptosis and TNF‐α signaling in sarcopenia are attenuated by life‐long calorie restriction

Phillips, T., & Leeuwenburgh, C. (2005) · The FASEB Journal · doi:10.1096/fj.04-2870fje · Cited by 283 · see citing works

Impact of Whole-Body Vibration Training Versus Fitness Training on Muscle Strength and Muscle Mass in Older Men: A 1-Year Randomized Controlled Trial

Bogaerts, A., Delecluse, C., Claessens, A. L., Coudyzer, W., Boonen, S., & Verschueren, S. M. P. (2007) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/62.6.630 · Cited by 283 · see citing works

Sarcopenia: Effects on Body Composition and Function

Roubenoff, R. (2003) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/58.11.m1012 · Cited by 282 · see citing works

Diet and its relationship with grip strength in community-dwelling older men and women: The Hertfordshire cohort study

Robinson, S. M., Jameson, K. A., Batelaan, S. F., Martin, H. J., Syddall, H. E., Dennison, E. M., Cooper, C., Sayer, A. A., & the Hertfordshire Cohort Study Group (2008) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2007.01478.x · Cited by 282 · see citing works

Hormonal and lifestyle determinants of appendicular skeletal muscle mass in men: the MINOS study

Szulc, P., Duboeuf, F., Marchand, F., & Delmas, P. D. (2004) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/80.2.496 · Cited by 280 · see citing works

Anthropometric estimation of muscle mass in men

MARTIN, A. D., Spenst, L. F., Drinkwater, D. T., & Clarys, J. P. (1990) · Medicine & Science in Sports & Exercise · doi:10.1249/00005768-199010000-00027 · Cited by 277 · see citing works

Human Sarcopenia Reveals an Increase in SOCS-3 and Myostatin and a Reduced Efficiency of Akt Phosphorylation

Léger, B., Derave, W., Bock, K. D., Hespel, P., & Russell, A. P. (2008) · Rejuvenation Research · doi:10.1089/rej.2007.0588 · Cited by 274 · see citing works

Waist Circumference, BMI, Smoking, and Mortality in Middle‐Aged Men and Women

Bigaard, J., Tjønneland, A. M., Thomsen, B. L., Overvad, K., Heitmann, B. L., & Sørensen, T. I. A. (2003) · Obesity Research · doi:10.1038/oby.2003.123 · Cited by 274 · see citing works

Creatine Supplementation Enhances Isometric Strength and Body Composition Improvements Following Strength Exercise Training in Older Adults

Brose, A., Parise, G., & Tarnopolsky, M. A. (2003) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/58.1.b11 · Cited by 274 · see citing works

Plasma 25-hydroxyvitamin D and its determinants in an elderly population sample

Jacques, P. F., Felson, D. T., Tucker, K. L., Mahnken, B., Wilson, P., Rosenberg, I. H., & Rush, D. (1997) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/66.4.929 · Cited by 270 · see citing works

Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors

Haidet, A. M., Rizo, L., Handy, C. R., Umapathi, P., Eagle, A., Shilling, C., Boué, D. R., Martin, P. T., Sahenk, Z., Mendell, J. R., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0709144105 · Cited by 267 · see citing works

Effects of High-Intensity Resistance Training on Untrained Older Men. I. Strength, Cardiovascular, and Metabolic Responses

Hagerman, F. C., Walsh, S., Staron, R. S., Hikida, R. S., Gilders, R. M., Murray, T. F., Toma, K., & Ragg, K. E. (2000) · The Journals of Gerontology Series A · doi:10.1093/gerona/55.7.b336 · Cited by 264 · see citing works

Identification of a molecular signature of sarcopenia

Giresi, P. G., Stevenson, E. J., Theilhaber, J., Koncarevic, A., Parkington, J. D., Fielding, R. A., & Kandarian, S. C. (2005) · Physiological Genomics · doi:10.1152/physiolgenomics.00249.2004 · Cited by 263 · see citing works

Correlates of Impaired Function in Older Women

Ensrud, K. E., Nevitt, M. C., Yunis, C., Cauley, J. A., Seeley, D. G., Fox, K. M., & Cummings, S. R. (1994) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1994.tb04968.x · Cited by 262 · see citing works

Heritability of body size and muscle strength in young adulthood: a study of one million Swedish men

Silventoinen, K., Magnusson, P. K. E., Tynelius, P., Kaprio, J., & Rasmussen, F. (2008) · Genetic Epidemiology · doi:10.1002/gepi.20308 · Cited by 261 · see citing works

Associated Factors and Health Impact of Sarcopenia in Older Chinese Men and Women: A Cross-Sectional Study

Lee, J. S. W., Auyeung, T.-W., Kwok, T., Lau, E. M. C., Leung, P.-C., & Woo, J. (2007) · Gerontology · doi:10.1159/000107355 · Cited by 247 · see citing works

Insulin-like growth factor-1 and interleukin 6 predict sarcopenia in very old community-living men and women: the Framingham Heart Study

Payette, H., Roubenoff, R., Jacques, P. F., Dinarello, C. A., Wilson, P. W. F., Abad, L. W., & Harris, T. (2003) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2003.51407.x · Cited by 245 · see citing works

Stimulation of In Vitro Rat Muscle Protein Synthesis by Leucine Decreases with Age

Dardevet, D. P., Sornet, C., Balage, M., & Grizard, J. (2000) · Journal of Nutrition · doi:10.1093/jn/130.11.2630 · Cited by 243 · see citing works

Body Mass Index Is Inversely Related to Mortality in Older People After Adjustment for Waist Circumference

Janssen, I., Katzmarzyk, P. T., & Ross, R. (2005) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2005.00505.x · Cited by 242 · see citing works

Sarcopenia is predictive of nosocomial infection in care of the elderly

Cosquéric, G., Sebag, A., Ducolombier, C., Thomas, C., Piette, F., & Weill‐Engerer, S. (2006) · British Journal Of Nutrition · doi:10.1017/bjn20061943 · Cited by 242 · see citing works

A Double-Blind, Placebo-Controlled, Randomized Clinical Trial of Transdermal Dihydrotestosterone Gel on Muscular Strength, Mobility, and Quality of Life in Older Men with Partial Androgen Deficiency

Ly, L. P., Jimenez, M., Zhuang, T. N., Celermajer, D. S., Conway, A. J., & Handelsman, D. J. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.9.7821 · Cited by 241 · see citing works

Histochemical and metabolic characteristics of human skeletal muscle in relation to age

Essén-Gustavsson, B., & Borges, O. (1986) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1986.tb07793.x · Cited by 238 · see citing works

Insulin resistance: a contributing factor to age-related muscle mass loss?

Guillet, C., & Boirie‌, Y. (2005) · Diabetes & Metabolism · doi:10.1016/s1262-3636(05)73648-x · Cited by 237 · see citing works

Effect of growth hormone and resistance exercise on muscle growth and strength in older men

Yarasheski, K. E., Zachwieja, J. J., Campbell, J. A., & Bier, D. M. (1995) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1995.268.2.e268 · Cited by 234 · see citing works

A 3-year longitudinal study on body composition changes in the elderly: Role of physical exercise

Raguso, C. A., Kyle, U. G., Kossovsky, M. P., Roynette, C. E., Paoloni‐Giacobino, A., Hans, D. B., Genton, L., & Pichard, C. (2005) · Clinical Nutrition · doi:10.1016/j.clnu.2005.10.013 · Cited by 234 · see citing works

Creatine supplementation combined with resistance training in older men

CHRUSCH, M. J., CHILIBECK, P. D., CHAD, K. E., SHAWN DAVISON, K., & BURKE, D. G. (2001) · Medicine &amp; Science in Sports &amp; Exercise · doi:10.1097/00005768-200112000-00021 · Cited by 233 · see citing works

Sarcopenic Obesity: Does Muscle Loss Cause Fat Gain?: Lessons from Rheumatoid Arthritis and Osteoarthritis a

Roubenoff, R. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06515.x · Cited by 230 · see citing works

Birth size, adult body composition and muscle strength in later life

Ylihärsilä, H., Kajantie, E., Osmond, C., Forsén, T., Barker, D. J. P., & Eriksson, J. G. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803612 · Cited by 226 · see citing works

Resistance exercise training increases mixed muscle protein synthesis rate in frail women and men ≥76 yr old

Yarasheski, K. E., Pak-Loduca, J., Hasten, D. L., Obert, K. A., Brown, M. B., & Sinacore, D. R. (1999) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1999.277.1.e118 · Cited by 226 · see citing works

Dual-Energy X-Ray Absorptiometry Is a Valid Tool for Assessing Skeletal Muscle Mass in Older Women ,

Chen, Z., Wang, Z., Lohman, T. G., Heymsfield, S. B., Outwater, E. K., Nicholas, J. S., Bassford, T. L., LaCroix, A. Z., Sherrill, D. L., Punyanitya, M., et al. (2007) · Journal of Nutrition · doi:10.1093/jn/137.12.2775 · Cited by 225 · see citing works

Coimpairments as Predictors of Severe Walking Disability in Older Women

Rantanen, T., Guralnik, J. M., Ferrucci, L., Penninx, B. W. J. H., Leveille, S. G., Sipilä, S., & Fried, L. P. (2001) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2001.49005.x · Cited by 225 · see citing works

Aerobic Exercise Overcomes the Age-Related Insulin Resistance of Muscle Protein Metabolism by Improving Endothelial Function and Akt/Mammalian Target of Rapamycin Signaling

Fujita, S., Rasmussen, B. B., Cadenas, J. G., Drummond, M. J., Glynn, E. L., Sattler, F. R., & Volpi, E. (2007) · Diabetes · doi:10.2337/db06-1566 · Cited by 224 · see citing works

Decreased expression of heat shock protein 70 mRNA and protein after heat treatment in cells of aged rats.

Fargnoli, J., Kunisada, T., Fornace, A. J., Schneider, E. L., & Holbrook, N. J. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.2.846 · Cited by 223 · see citing works

Mitochondrial abnormalities are more frequent in muscles undergoing sarcopenia

Bua, E. A., McKiernan, S. H., Wanagat, J., McKenzie, D., & Aiken, J. M. (2002) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01102.2001 · Cited by 223 · see citing works

Invited Review: Aging and energy balance

Wilson, M. G., & Morley, J. E. (2003) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00313.2003 · Cited by 221 · see citing works

Functional and Metabolic Consequences of Sarcopenia

Evans, W. J. (1997) · Journal of Nutrition · doi:10.1093/jn/127.5.998s · Cited by 220 · see citing works

Atrophy-related ubiquitin ligases, atrogin-1 and MuRF1 are up-regulated in aged rat Tibialis Anterior muscle

Clavel, S., Coldefy, A.-S., Kurkdjian, E., Salles, J., Margaritis, I., & Dérijard, B. (2006) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2006.07.005 · Cited by 218 · see citing works

Body Mass Index and Mortality Among Older People Living in the Community

Landi, F., Zuccalà, G., Gambassi, G., Incalzi, R. A., Manigrasso, L., Pagano, F. C., Carbonin, P., & Bernabei, R. (1999) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1999.tb05229.x · Cited by 218 · see citing works

Falls Relate to Vitamin D and Parathyroid Hormone in an Australian Nursing Home and Hostel

Stein, M. S., Wark, J. D., Scherer, S. C., Walton, S. L., Chick, P., Carlantonio, M. D., Zajac, J. D., & Flicker, L. A. (1999) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1999.tb05199.x · Cited by 217 · see citing works

Does Sarcopenia Originate in Early Life? Findings From the Hertfordshire Cohort Study

Sayer, A. A., Syddall, H. E., Gilbody, H., Dennison, E. M., & Cooper, C. C. (2004) · The Journals of Gerontology Series A · doi:10.1093/gerona/59.9.m930 · Cited by 214 · see citing works

Large energetic adaptations of elderly muscle to resistance and endurance training

Jubrias, S. A., Esselman, P. C., Price, L. B., Cress, M. E., & Conley, K. E. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.90.5.1663 · Cited by 213 · see citing works

Hand grip strength: A phenotype suitable for identifying genetic variants affecting mid‐ and late‐life physical functioning

Frederiksen, H., Gaist, D., Petersen, H. C., Hjelmborg, J., McGue, M. K., Vaupel, J. W., & Christensen, K. (2002) · Genetic Epidemiology · doi:10.1002/gepi.1127 · Cited by 209 · see citing works

Apoptosis in muscle atrophy: Relevance to sarcopenia

Dupont‐Versteegden, E. E. (2005) · Experimental Gerontology · doi:10.1016/j.exger.2005.04.003 · Cited by 207 · see citing works

Myostatin Inhibits Myogenesis and Promotes Adipogenesis in C3H 10T(1/2) Mesenchymal Multipotent Cells

Artaza, J. N., Bhasin, S., Magee, T. R., Reisz‐Porszasz, S., Shen, R., Groome, N. P., Fareez, M. M., & González-Cadavid, N. F. (2005) · Endocrinology · doi:10.1210/en.2005-0362 · Cited by 207 · see citing works

Reductions in Plasma Cytokine Levels With Weight Loss Improve Insulin Sensitivity in Overweight and Obese Postmenopausal Women

Ryan, A. S., & Nicklas, B. J. (2004) · Diabetes Care · doi:10.2337/diacare.27.7.1699 · Cited by 207 · see citing works

Association of IGF-I levels with muscle strength and mobility in older women

Cappola, A. R., Bandeen-Roche, K., Wand, G. S., Volpato, S., & Fried, L. P. (2001) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jcem.86.9.7868 · Cited by 205 · see citing works

Intermuscular adipose tissue-free skeletal muscle mass: estimation by dual-energy X-ray absorptiometry in adults

Kim, J., Heshka, S., Gallagher, D., Kotler, D. P., Mayer, L., Albu, J., Shen, W., Freda, P. U., & Heymsfield, S. B. (2004) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00260.2004 · Cited by 205 · see citing works

Serum Testosterone and the Risk of Prostate Cancer: Potential Implications for Testosterone Therapy

Parsons, J. K., Carter, H. B., Platz, E. A., Wright, E. J., Landis, P., & Metter, E. J. (2005) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-04-0715 · Cited by 203 · see citing works

Estimation of body composition from bioelectric impedance of body segments

Baumgartner, R. N., Chumlea, W. C., & Roche, A. F. (1989) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/50.2.221 · Cited by 201 · see citing works

Estrogen Receptor Alpha mRNA in Human Skeletal Muscles

LEMOINE, S., GRANIER, P., TIFFOCHE, C., RANNOU-BEKONO, F., THIEULANT, M.-L., & DELAMARCHE, P. (2003) · Medicine &amp; Science in Sports &amp; Exercise · doi:10.1249/01.mss.0000053654.14410.78 · Cited by 201 · see citing works

17β‐estradiol regulates cytokine release through modulation of CD16 expression in monocytes and monocyte‐derived macrophages

Kramer, P. R., Kramer, S. F., & Guan, G. (2004) · Arthritis & Rheumatism · doi:10.1002/art.20309 · Cited by 200 · see citing works

Safety of antitumour necrosis factor (anti-TNF) therapy in patients with chronic viral infections: hepatitis C, hepatitis B, and HIV infection

Calabrese, L. H., Zein, N., & Vassilopoulos, D. (2004) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2004.028209 · Cited by 197 · see citing works

Postexercise protein metabolism in older and younger men following moderate-intensity aerobic exercise

Sheffield-Moore, M., Yeckel, C. W., Volpi, E., Wolf, S. E., Morio, B., Chinkes, D. L., Paddon-Jones, D., & Wolfe, R. R. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00334.2003 · Cited by 197 · see citing works

Atrogin-1/MAFbx and MuRF1 are downregulated in aging-related loss of skeletal muscle

Edstrom, E., Altun, M., Hagglund, M., & Ulfhake, B. (2006) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/61.7.663 · Cited by 196 · see citing works

Quadriceps and Grip Strength Are Related to Vitamin D Receptor Genotype in Elderly Nonobese Women

Geusens, P., Vandevyver, C. D. B., Vanhoof, J., Cassiman, J., Boonen, S., & Raus, J. (1997) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1997.12.12.2082 · Cited by 193 · see citing works

Amino Acids and Muscle Loss with Aging

Fujita, S., & Volpi, E. (2006) · Journal of Nutrition · doi:10.1093/jn/136.1.277s · Cited by 191 · see citing works

Myofibrillar protein synthesis in young and old human subjects after three months of resistance training

Welle, S. L., Thornton, C. A., & Statt, M. (1995) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1995.268.3.e422 · Cited by 190 · see citing works

Effects of an omnivorous diet compared with a lactoovovegetarian diet on resistance-training-induced changes in body composition and skeletal muscle in older men

Campbell, W. W., Barton, M. L., Cyr-Campbell, D., Davey, S. L., Beard, J. L., Parise, G., & Evans, W. J. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/70.6.1032 · Cited by 190 · see citing works

Cytokine-Related Aging Process

Morley, J. E., & Baumgartner, R. (2004) · The Journals of Gerontology Series A · doi:10.1093/gerona/59.9.m924 · Cited by 189 · see citing works

Transgenic expression of a myostatin inhibitor derived from follistatin increases skeletal muscle mass and ameliorates dystrophic pathology in mdx mice

Nakatani, M., Takehara, Y., Sugino, H., Matsumoto, M., Hashimoto, O., Hasegawa, Y., Murakami, T., Uezumi, A., Takeda, S., Noji, S., et al. (2007) · The FASEB Journal · doi:10.1096/fj.07-8673com · Cited by 187 · see citing works

Effects of Oral Creatine and Resistance Training on Myogenic Regulatory Factor Expression

WILLOUGHBY, D. S., & ROSENE, J. M. (2003) · Medicine &amp; Science in Sports &amp; Exercise · doi:10.1249/01.mss.0000069746.05241.f0 · Cited by 186 · see citing works

Knee Extensor and Knee Flexor Strength:Cross-Sectional Area Ratios in Young and Elderly Men

Overend, T. J., Cunningham, D. A., Kramer, J. F., Lefcoe, M. S., & Paterson, D. H. (1992) · Journal of Gerontology · doi:10.1093/geronj/47.6.m204 · Cited by 186 · see citing works

Smoking impairs muscle protein synthesis and increases the expression of myostatin and MAFbx in muscle

Petersen, A. M. W., Magkos, F., Atherton, P. J., Selby, A., Smith, K., Rennie, M. J., Pedersen, B. K., & Mittendorfer, B. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00301.2007 · Cited by 185 · see citing works

Sarcopenia: European consensus on definition and diagnosis

Cruz-Jentoft, A. J., Baeyens, J. P., Bauer, J. M., Boirie, Y., Cederholm, T., Landi, F., Martin, F. C., Michel, J.-P., Rolland, Y., Schneider, S. M., et al. (2010) · Age and Ageing · doi:10.1093/ageing/afq034 · Cited by 11,601 · see citing works

Sarcopenia in Asia: Consensus Report of the Asian Working Group for Sarcopenia

Chen, L.-K., Liu, L.-K., Woo, J., Assantachai, P., Auyeung, T.-W., Bahyah, K. S., Chou, M.-Y., Chen, L.-Y., Hsu, P.-S., Krairit, O., et al. (2014) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2013.11.025 · Cited by 4,051 · see citing works

Sarcopenia, dynapenia, and the impact of advancing age on human skeletal muscle size and strength; a quantitative review

Mitchell, W. K., Williams, J., Atherton, P., Larvin, M., Lund, J., & Narici, M. (2012) · Frontiers in Physiology · doi:10.3389/fphys.2012.00260 · Cited by 1,377 · see citing works

SARC-F: a symptom score to predict persons with sarcopenia at risk for poor functional outcomes

Malmstrom, T. K., Miller, D. K., Simonsick, E. M., Ferrucci, L., & Morley, J. E. (2016) · Journal of Cachexia, Sarcopenia and Muscle · doi:10.1002/jcsm.12048 · Cited by 1,155 · see citing works

Sarcopenia with limited mobility: an international consensus

Morley, J. E., Abbatecola, A. M., Argiles, J. M., Baracos, V., Bauer, J., Bhasin, S., Cederholm, T., Stewart Coats, A. J., Cummings, S. R., Evans, W. J., et al. (2011) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2011.04.014 · Cited by 1,125 · see citing works

Skeletal muscle performance and ageing

Tieland, M., Trouwborst, I., & Clark, B. C. (2018) · Journal of Cachexia, Sarcopenia and Muscle · doi:10.1002/jcsm.12238 · Cited by 904 · see citing works

Protein supplementation augments the adaptive response of skeletal muscle to resistance-type exercise training: a meta-analysis

Cermak, N. M., Res, P. T., de Groot, L. C., Saris, W. H., & van Loon, L. J. (2012) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.037556 · Cited by 827 · see citing works

Nutritional recommendations for the management of sarcopenia

Morley, J. E., Argiles, J. M., Evans, W. J., Bhasin, S., Cella, D., Deutz, N. E. P., Doehner, W., Fearon, K. C. H., Ferrucci, L., Hellerstein, M. K., et al. (2010) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2010.04.014 · Cited by 664 · see citing works

Muscle wasting in patients with chronic heart failure: results from the studies investigating co-morbidities aggravating heart failure (SICA-HF)

Fulster, S., Tacke, M., Sandek, A., Ebner, N., Tschope, C., Doehner, W., Anker, S. D., & von Haehling, S. (2013) · European Heart Journal · doi:10.1093/eurheartj/ehs381 · Cited by 658 · see citing works

Understanding sarcopenia as a geriatric syndrome

Cruz-Jentoft, A. J., Landi, F., Topinková, E., & Michel, J.-P. (2010) · Current Opinion in Clinical Nutrition and Metabolic Care · doi:10.1097/mco.0b013e328333c1c1 · Cited by 602 · see citing works

Sarcopenic obesity: a critical appraisal of the current evidence

Prado, C. M. M., Wells, J. C. K., Smith, S. R., Stephan, B. C. M., & Siervo, M. (2012) · Clinical Nutrition · doi:10.1016/j.clnu.2012.06.010 · Cited by 589 · see citing works

Protein Supplementation Increases Muscle Mass Gain During Prolonged Resistance-Type Exercise Training in Frail Elderly People: A Randomized, Double-Blind, Placebo-Controlled Trial

Tieland, M., Dirks, M. L., van der Zwaluw, N., Verdijk, L. B., van de Rest, O., de Groot, L. C. P. G. M., & van Loon, L. J. C. (2012) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2012.05.020 · Cited by 556 · see citing works

Validity and Reliability of Tools to Measure Muscle Mass, Strength, and Physical Performance in Community-Dwelling Older People: A Systematic Review

Mijnarends, D. M., Meijers, J. M. M., Halfens, R. J. G., ter Borg, S., Luiking, Y. C., Verlaan, S., Schoberer, D., Cruz Jentoft, A. J., van Loon, L. J. C., & Schols, J. M. G. A. (2013) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2012.10.009 · Cited by 475 · see citing works

Predicted lean body mass, fat mass, and all cause and cause specific mortality in men: Prospective us cohort study

Lee, D. H., Keum, N., Hu, F. B., Orav, E. J., Rimm, E. B., Willett, W. C., & Giovannucci, E. L. (2018) · BMJ · doi:10.1136/bmj.k2575 · Cited by 486 · see citing works

Protein Supplementation Improves Physical Performance in Frail Elderly People: A Randomized, Double-Blind, Placebo-Controlled Trial

Tieland, M., van de Rest, O., Dirks, M. L., van der Zwaluw, N., Mensink, M., van Loon, L. J. C., & de Groot, L. C. P. G. M. (2012) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2012.07.005 · Cited by 446 · see citing works

Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging

Andersson, D. C., Betzenhauser, M. J., Reiken, S., Meli, A. C., Umanskaya, A., Xie, W., Shiomi, T., Zalk, R., Lacampagne, A., & Marks, A. R. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.05.014 · Cited by 424 · see citing works

Exercise Attenuates the Major Hallmarks of Aging

Garatachea, N., Pareja-Galeano, H., Sanchis-Gomar, F., Santos-Lozano, A., Fiuza-Luces, C., Morán, M., Emanuele, E., Joyner, M. J., & Lucia, A. (2015) · Rejuvenation Research · doi:10.1089/rej.2014.1623 · Cited by 413 · see citing works

Determinants of Muscle and Bone Aging

Curtis, E., Litwic, A., Cooper, C., & Dennison, E. (2015) · Journal of Cellular Physiology · doi:10.1002/jcp.25001 · Cited by 375 · see citing works

Functional and/or structural brain changes in response to resistance exercises and resistance training lead to cognitive improvements – a systematic review

Herold, F., Törpel, A., Schega, L., & Müller, N. G. (2019) · European Review of Aging and Physical Activity · doi:10.1186/s11556-019-0217-2 · Cited by 349 · see citing works

Models of accelerated sarcopenia: critical pieces for solving the puzzle of age-related muscle atrophy

Buford, T. W., Anton, S. D., Judge, A. R., Marzetti, E., Wohlgemuth, S. E., Carter, C. S., Leeuwenburgh, C., Pahor, M., & Manini, T. M. (2010) · Ageing Research Reviews · doi:10.1016/j.arr.2010.04.004 · Cited by 295 · see citing works

Dietary protein intake in community-dwelling, frail, and institutionalized elderly people: scope for improvement

Tieland, M., Borgonjen-Van den Berg, K. J., van Loon, L. J. C., & de Groot, L. C. P. G. M. (2012) · European Journal of Nutrition · doi:10.1007/s00394-011-0203-6 · Cited by 297 · see citing works

Successful aging: Advancing the science of physical independence in older adults

Anton, S. D., Woods, A. J., Ashizawa, T., Barb, D., Buford, T. W., Carter, C. S., Clark, D. J., Cohen, R. A., Corbett, D. B., Cruz-Almeida, Y., et al. (2015) · Ageing Research Reviews · doi:10.1016/j.arr.2015.09.005 · Cited by 292 · see citing works

Osteosarcopenic obesity: the role of bone, muscle, and fat on health

Ormsbee, M. J., Prado, C. M., Ilich, J. Z., Purcell, S., Siervo, M., Folsom, A., & Panton, L. (2014) · Journal of Cachexia, Sarcopenia and Muscle · doi:10.1007/s13539-014-0146-x · Cited by 257 · see citing works

Inhibition of prostaglandin-degrading enzyme 15-PGDH rejuvenates aged muscle mass and strength

Palla, A. R., Ravichandran, M., Wang, Y. X., Alexandrova, L., Yang, A. V., Kraft, P., Holbrook, C. A., Schürch, C. M., Ho, A. T. V., & Blau, H. M. (2021) · Science · doi:10.1126/science.abc8059 · Cited by 232 · see citing works

Exercise and nutrition strategies to counteract sarcopenic obesity

Trouwborst, I., Verreijen, A., Memelink, R., Massanet, P., Boirie, Y., Weijs, P., & Tieland, M. (2018) · Nutrients · doi:10.3390/nu10050605 · Cited by 210 · see citing works

Relationship between relative skeletal muscle mass and nonalcoholic fatty liver disease: A 7-year longitudinal study

Kim, G., Lee, S., Lee, Y., Jun, J. E., Ahn, J., Bae, J. C., Jin, S., Hur, K. Y., Jee, J. H., Lee, M., et al. (2018) · Hepatology · doi:10.1002/hep.30049 · Cited by 198 · see citing works

Sarcopenia and obesity

Waters, D. L., & Baumgartner, R. N. (2011) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2011.03.007 · Cited by 185 · see citing works

Sarcopenia: prevalence, mechanisms, and functional consequences

Berger, M. J., & Doherty, T. J. (2010) · Interdisciplinary topics in gerontology and geriatrics · doi:10.1159/000319997 · Cited by 175 · see citing works

Mitochondrial death effectors: Relevance to sarcopenia and disuse muscle atrophy

Marzetti, E., Hwang, J. C. Y., Lees, H. A., Wohlgemuth, S. E., Dupont-Versteegden, E. E., Carter, C. S., Bernabei, R., & Leeuwenburgh, C. (2010) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2009.05.007 · Cited by 174 · see citing works

Assessment of computed tomography (CT)-defined muscle and adipose tissue features in relation to short-term outcomes after elective surgery for colorectal cancer: a multicenter approach

Martin, L., Hopkins, J., Malietzis, G., Jenkins, J. T., Sawyer, M. B., Brisebois, R., MacLean, A., Nelson, G., Gramlich, L., & Baracos, V. E. (2018) · Annals of Surgical Oncology · doi:10.1245/s10434-018-6652-x · Cited by 139 · see citing works

Discovering pathways of sarcopenia in older adults: a role for insulin resistance on mitochondria dysfunction

Abbatecola, A. M., Paolisso, G., Fattoretti, P., Evans, W. J., Fiore, V., Dicioccio, L., & Lattanzio, F. (2011) · The Journal of nutrition, health and aging · doi:10.1007/s12603-011-0366-0 · Cited by 137 · see citing works

Sarcopenia as a predictor of all-cause mortality among older nursing home residents: A systematic review and meta-analysis

Zhang, X., Wang, C., Dou, Q., Zhang, W., Yang, Y., & Xie, X. (2018) · BMJ Open · doi:10.1136/bmjopen-2017-021252 · Cited by 127 · see citing works

Effects of Popular Diets without Specific Calorie Targets on Weight Loss Outcomes: Systematic Review of Findings from Clinical Trials

Anton, S., Hida, A., Heekin, K., Sowalsky, K., Karabetian, C., Mutchie, H., Leeuwenburgh, C., Manini, T., & Barnett, T. (2017) · Nutrients · doi:10.3390/nu9080822 · Cited by 125 · see citing works

The impact of dietary protein or amino acid supplementation on muscle mass and strength in elderly people: Individual participant data and meta-analysis of RCT's

Tieland, M., Franssen, R., Dullemeijer, C., van Dronkelaar, C., Kim, H. K., Ispoglou, T., Zhu, K., Prince, R. L., van Loon, L. J. C., & de Groot, L. C. P. G. M. (2017) · The Journal of nutrition, health and aging · doi:10.1007/s12603-017-0896-1 · Cited by 123 · see citing works

Sarcopenic obesity as an independent risk factor of hypertension

Park, S. H., Park, J. H., Song, P. S., Kim, D. K., Kim, K. H., Seol, S. H., Kim, H. K., Jang, H. J., Lee, J. G., Park, H. Y., et al. (2013) · Journal of the American Society of Hypertension · doi:10.1016/j.jash.2013.06.002 · Cited by 118 · see citing works

Prevalence of Sarcopenia in Geriatric Hospitalized Patients

Smoliner, C., Sieber, C. C., & Wirth, R. (2014) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2013.11.027 · Cited by 117 · see citing works

Changes in IL-15 expression and death-receptor apoptotic signaling in rat gastrocnemius muscle with aging and life-long calorie restriction

Marzetti, E., Carter, C. S., Wohlgemuth, S. E., Lees, H. A., Giovannini, S., Anderson, B., Quinn, L. S., & Leeuwenburgh, C. (2009) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2008.12.008 · Cited by 113 · see citing works

Equation models developed with bioelectric impedance analysis tools to assess muscle mass: a systematic review.

Beaudart, C., Bruyère, O., Geerinck, A., Hajaoui, M., Scafoglieri, A., Perkisas, S., Bautmans, I., Gielen, E., Reginster, J.-Y., & Buckinx, F. (2020) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2019.09.012 · Cited by 113 · see citing works

Methods, Diagnostic Criteria, Cutoff Points, and Prevalence of Sarcopenia among Older People

Pagotto, V., & Silveira, E. A. (2014) · The Scientific World Journal · doi:10.1155/2014/231312 · Cited by 100 · see citing works

Sarcopenic obesity: An appraisal of the current status of knowledge and management in elderly people

Molino, S., Dossena, M., Buonocore, D., & Verri, M. (2016) · The Journal of nutrition, health and aging · doi:10.1007/s12603-015-0631-8 · Cited by 91 · see citing works

Inactivity‐induced oxidative stress: A central role in age‐related sarcopenia?

Derbré, F., Gratas‐Delamarche, A., Gómez‐Cabrera, M. C., & Viña, J. (2014) · European Journal of Sport Science · doi:10.1080/17461391.2011.654268 · Cited by 89 · see citing works

Myostatin – The Holy Grail for Muscle, Bone, and Fat?

Buehring, B., & Binkley, N. (2013) · Current Osteoporosis Reports · doi:10.1007/s11914-013-0160-5 · Cited by 79 · see citing works

Drastic increase of myosin light chain MLC-2 in senescent skeletal muscle indicates fast-to-slow fibre transition in sarcopenia of old age

Gannon, J., Doran, P., Kirwan, A., & Ohlendieck, K. (2009) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2009.06.004 · Cited by 74 · see citing works

Lower Dietary and Circulating Vitamin C in Middle- and Older-Aged Men and Women Are Associated with Lower Estimated Skeletal Muscle Mass

Lewis, L. N., Hayhoe, R. P., Mulligan, A. A., Luben, R. N., Khaw, K.-T., & Welch, A. A. (2020) · The Journal of Nutrition · doi:10.1093/jn/nxaa221 · Cited by 72 · see citing works

<scp>PGC</scp>‐1α affects aging‐related changes in muscle and motor function by modulating specific exercise‐mediated changes in old mice

Gill, J. F., Santos, G., Schnyder, S., & Handschin, C. (2018) · Aging Cell · doi:10.1111/acel.12697 · Cited by 72 · see citing works

Association of thyroid function with sarcopenia in elderly Chinese euthyroid subjects

Sheng, Y., Ma, D., Zhou, Q., Wang, L., Sun, M., Wang, S., Qi, H., Liu, J., Ding, G., & Duan, Y. (2019) · Aging Clinical and Experimental Research · doi:10.1007/s40520-018-1057-z · Cited by 65 · see citing works

Impaired Mitochondrial Energetics Characterize Poor Early Recovery of Muscle Mass Following Hind Limb Unloading in Old Mice

Zhang, X., Trevino, M. B., Wang, M., Gardell, S. J., Ayala, J. E., Han, X., Kelly, D. P., Goodpaster, B. H., Vega, R. B., & Coen, P. M. (2018) · The Journals of Gerontology: Series A · doi:10.1093/gerona/gly051 · Cited by 58 · see citing works

Late-Life Onset Hypogonadism: A Review

Bassil, N., & Morley, J. E. (2010) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2010.02.003 · Cited by 59 · see citing works

Improved Calcium Homeostasis and Force by Selenium Treatment and Training in Aged Mouse Skeletal Muscle

Fodor, J., Al-Gaadi, D., Czirják, T., Oláh, T., Dienes, B., Csernoch, L., & Szentesi, P. (2020) · Scientific Reports · doi:10.1038/s41598-020-58500-x · Cited by 53 · see citing works

Endothelial function and the regulation of muscle protein anabolism in older adults

Timmerman, K. L., & Volpi, E. (2013) · Nutrition, Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2012.03.013 · Cited by 53 · see citing works

Type 2 diabetes and impaired physical function: a growing problem

Ahmad, E., Sargeant, J. A., Yates, T., Webb, D. R., & Davies, M. J. (2022) · Diabetology · doi:10.3390/diabetology3010003 · Cited by 52 · see citing works

Novel Sarcopenia-related Alterations in Sarcomeric Protein Post-translational Modifications (PTMs) in Skeletal Muscles Identified by Top-down Proteomics

Wei, L., Gregorich, Z. R., Lin, Z., Cai, W., Jin, Y., McKiernan, S. H., McIlwain, S., Aiken, J. M., Moss, R. L., Diffee, G. M., et al. (2018) · Molecular &amp; Cellular Proteomics · doi:10.1074/mcp.ra117.000124 · Cited by 47 · see citing works

Power Versus Sarcopenia: Associations with Functionality and Physical Performance Measures

Bahat, G., Kilic, C., Eris, S., & Karan, M. A. (2021) · The Journal of nutrition, health and aging · doi:10.1007/s12603-020-1544-8 · Cited by 45 · see citing works

Endothelin-1 induces cellular senescence and fibrosis in cultured myoblasts. A potential mechanism of aging-related sarcopenia

Alcalde-Estévez, E., Asenjo-Bueno, A., Sosa, P., Olmos, G., Plaza, P., Caballero-Mora, M. Á., Rodríguez-Puyol, D., Ruíz-Torres, M. P., & López-Ongil, S. (2020) · Aging · doi:10.18632/aging.103450 · Cited by 35 · see citing works

Sarcopenia, but not sarcopenic obesity, predicts mortality for older old men: a 3-year prospective cohort study

Liu, L.-K., Chen, L.-Y., Yeh, K.-P., Lin, M.-H., Hwang, A.-C., Peng, L.-N., & Chen, L.-K. (2014) · Journal of Clinical Gerontology and Geriatrics · doi:10.1016/j.jcgg.2014.01.002 · Cited by 26 · see citing works

Psoas and paraspinous muscle index as a predictor of mortality in African American men with type 2 diabetes mellitus

Murea, M., Lenchik, L., Register, T. C., Russell, G. B., Xu, J., Smith, S. C., Bowden, D. W., Divers, J., & Freedman, B. I. (2018) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2018.03.004 · Cited by 22 · see citing works

Do frail older persons need more protein?

Morley, J. E. (2012) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2012.07.014 · Cited by 21 · see citing works

The Crossroads of Aging: An Intersection of Malnutrition, Frailty, and Sarcopenia

Severin, R., Berner, P. M., Miller, K. L., & Mey, J. (2019) · Topics in Geriatric Rehabilitation · doi:10.1097/tgr.0000000000000218 · Cited by 19 · see citing works

A Humble Opinion on the Changeable Rule of the Acute Stage of Cerebral Hemorrhage Etiology and Pathogenesis

Liu, T. (2015) · Liaoning zhongyi zazhi

Etiology and Pathogenesis of Pericarditis from the Perspective of Traditional Chinese and Western Medicine

Li, F., & Zheng, G. (2021) · Proceedings of Anticancer Research · doi:10.26689/par.v5i5.2588

The Impact of Low Muscle Mass Definition on the Prevalence of Sarcopenia in Older Australians

Yu, S., Appleton, S., Adams, R., Chapman, I., Wittert, G., Visvanathan, T., & Visvanathan, R. (2014) · BioMed Research International · doi:10.1155/2014/361790 · Cited by 34 · see citing works

Prevalence of sarcopenia among community- dwelling, young elderly people living in Manizales, Colombia

GONZÁLEZ-GONZÁLEZ, D., Lopez-Salazar, A. M., González-Correa, C. H., & Curcio, C. (2019) · Journal of Physics Conference Series · doi:10.1088/1742-6596/1272/1/012005 · Cited by 1 · see citing works

Epidemiology and consequences of sarcopenia

van Kan, G. A. (2009) · The journal of nutrition health & aging · doi:10.1007/s12603-009-0201-z · Cited by 344 · see citing works