The DOI matches its Crossref record; 61 of the 61 references it cites were found in a registry or an index.
Discrimination Between Normal and Cancerous Cells Using AFM
Open accessAbstract
Currently, biomechanics of living cells is in the focus of interest due to noticeable capability of such techniques like atomic force microscopy (AFM) to probe cellular properties at the single cell level directly on living cells. The research carried out, so far, delivered data showing, on the one hand, the use of cellular mechanics as a biomarker of various pathological changes, which, on the other hand, reveal relative nature of biomechanics. In the AFM, the elastic properties of living cells are delivered from indentation experiments and described quantitatively by Young's modulus defined here as a measure of cellular deformability. Here, the AFM studies directly comparing the mechanical properties of normal and cancerous cells are summarized and presented together with a few important issues related to the relativeness of Young's modulus.
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Cites
Hallmarks of Cancer: The Next Generation
Hanahan, D., & Weinberg, R. A. (2011) · Cell · doi:10.1016/j.cell.2011.02.013 · Cited by 66,590
Ueber die Berührung fester elastischer Körper.
Hertz, H. (1882) · crll · doi:10.1515/crll.1882.92.156 · Cited by 4,789
Sneddon, I. N. (1965) · International Journal of Engineering Science · doi:10.1016/0020-7225(65)90019-4 · Cited by 4,346
Tensional homeostasis and the malignant phenotype
Paszek, M. J., Zahir, N., Johnson, K. R., Lakins, J. N., Rozenberg, G. I., Gefen, A., Reinhart-King, C. A., Margulies, S. S., Dembo, M., Boettiger, D., et al. (2005) · Cancer Cell · doi:10.1016/j.ccr.2005.08.010 · Cited by 3,941
On the Contact of Elastic Solids
Hertz (1882) · Journal für die reine und angewandte Mathematik (Crelles Journal) · Cited by 3,051
Nanomechanical analysis of cells from cancer patients
Cross, S. E., Jin, Y.-S., Rao, J., & Gimzewski, J. K. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.388 · Cited by 1,908
Elastic Moduli of Breast and Prostate Tissues under Compression
Krouskop, T. A., Wheeler, T. M., Kallel, F., Garra, B. S., & Hall, T. (1998) · Ultrasonic Imaging · doi:10.1177/016173469802000403 · Cited by 1,703
Guck, J., Schinkinger, S., Lincoln, B., Wottawah, F., Ebert, S., Romeyke, M., Lenz, D., Erickson, H. M., Ananthakrishnan, R., Mitchell, D., et al. (2005) · Biophysical Journal · doi:10.1529/biophysj.104.045476 · Cited by 1,417
Collagen density promotes mammary tumor initiation and progression
Provenzano, P. P., Inman, D. R., Eliceiri, K. W., Knittel, J. G., Yan, L., Rueden, C. T., White, J. G., & Keely, P. J. (2008) · BMC Medicine · doi:10.1186/1741-7015-6-11 · Cited by 1,361
Regulation of the actin cytoskeleton in cancer cell migration and invasion
Yamaguchi, H., & Condeelis, J. (2007) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2006.07.001 · Cited by 1,144
Cited by
The stiffness of living tissues and its implications for tissue engineering
Guimarães, C. F., Gasperini, L., Marques, A. P., & Reis, R. L. (2020) · Nature Reviews Materials · doi:10.1038/s41578-019-0169-1 · Cited by 1,515
Biophysics of tumor microenvironment and cancer metastasis – a mini review
Emon, B., Bauer, J., Jain, Y., Jung, B., & Saif, T. (2018) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2018.07.003 · Cited by 245
Metadata
- Authors
- Lekka, M.
- Venue
- BioNanoScience
- Published
- 2016-01-30
- Volume
- 6
- Issue
- 1
- Pages
- 65-80
- ISSN
- 2191-1630 (ISSN-L)
- 2191-1649
- OpenAlex
- W2268717463
- Cited by
- 414
- References
- 61
- FWCI
- 25.82
- Type
- journal article
- Language
- en
- Open access
- hybrid
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