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Cited by 339

The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.

Rosacea: New Concepts in Classification and Treatment

Open access
van Zuuren, Esther J., Arents, Bernd W. M., van der Linden, Mireille M. D., Vermeulen, Sofieke, Fedorowicz, Zbys, Tan, Jerry·2021·American Journal of Clinical Dermatology

Abstract

Rosacea is a chronic inflammatory dermatosis mainly affecting the cheeks, nose, chin, and forehead. Rosacea is characterized by recurrent episodes of flushing or transient erythema, persistent erythema, phymatous changes, papules, pustules, and telangiectasia. The eyes may also be involved. Due to rosacea affecting the face, it has a profound negative impact on quality of life, self-esteem, and well-being. In addition to general skin care, there are several approved treatment options available for addressing these features, both topical and systemic. For some features, intense pulse light, laser, and surgery are of value. Recent advances in fundamental scientific research have underscored the roles of the innate and adaptive immune systems as well as neurovascular dysregulation underlying the spectrum of clinical features of rosacea. Endogenous and exogenous stimuli may initiate and aggravate several pathways in patients with rosacea. This review covers the new phenotype-based diagnosis and classification system reflecting pathophysiology, and new and emerging treatment options and approaches. We address new topical and systemic formulations, as well as recent evidence on treatment combinations. In addition, ongoing studies investigating novel therapeutic interventions will be summarized.

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Metadata

Authors
van Zuuren, E. J., Arents, B. W. M., van der Linden, M. M. D., Vermeulen, S., Fedorowicz, Z., & Tan, J.
Venue
American Journal of Clinical Dermatology
Published
2021-03-23
Volume
22
Issue
4
Pages
457-465
ISSN
  • 1175-0561 (ISSN-L)
  • 1179-1888
OpenAlex
W3137117524
Cited by
339
References
32
FWCI
39.09
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Rosacea: New Concepts in Classification and Treatment. https://app.cochat.ai/papers/10.1007/s40257-021-00595-7
The paper
van Zuuren, E. J., Arents, B. W. M., van der Linden, M. M. D., Vermeulen, S., Fedorowicz, Z., & Tan, J. (2021). Rosacea: New Concepts in Classification and Treatment. American Journal of Clinical Dermatology. https://doi.org/10.1007/s40257-021-00595-7

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.