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Is Muscular Fitness Associated with Future Health Benefits in Children and Adolescents? A Systematic Review and Meta-Analysis of Longitudinal Studies
Abstract
Background No previous systematic review has quantitatively examined the association between muscular fitness during childhood and adolescence and health parameters later in life.Objective The aim was to systematically review and meta-analyze the current evidence for a prospective association between muscular fitness in childhood and adolescence and future health status.Methods Two authors systematically searched MEDLINE, EMBASE and SPORTDiscus electronic databases and conducted manual searching of reference lists of selected articles. Relevant articles were identified by the following criteria: apparently healthy children and adolescents aged 3-18 years with muscular fitness assessed at baseline (e.g., handgrip, standing long jump, sit-ups, among others), and a follow-up period of ≥ 1 year. The outcome measures were anthropometric and adiposity measurements and cardiometabolic, bone and musculoskeletal health parameters. Two authors independently extracted data.Results Thirty studies were included in the meta-analysis, yielding a total of 21,686 participants. The meta-analysis found a significant, moderate-large (p < 0.05) effect size between muscular fitness at baseline and body mass index (r = - 0.14; 95% confidence interval (CI) - 0.21 to - 0.07), skinfold thickness (r = - 0.32; 95% CI - 0.40 to - 0.23), homeostasis model assessment estimated insulin resistance (r = - 0.10; 95% CI - 0.16 to - 0.05), triglycerides (r = - 0.22; 95% CI - 0.30 to - 0.13), cardiovascular disease risk score (r = - 0.29; 95% CI - 0.39 to - 0.18), and bone mineral density (r = 0.166; 95% CI 0.086 to 0.243) at follow-up.Conclusion A prospective negative association was observed between muscular fitness in childhood/adolescence and adiposity and cardiometabolic parameters in later life, together with a positive association for bone health. There is inconclusive evidence for low back pain benefits.
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“Children and adolescents with better muscular fitness (eg, gained through exercises involving hand grip, standing, long jump and sit-ups) were shown to have better health outcomes (ie, lower levels of BMI and body fat, improvement in insulin resistance and lower levels of cardiovascular disease risk) in later life.68”
From Physical activity and health in Chinese children and adolescents: expert consensus statement (2020) (2020) · cites this paper as [68]
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“The available studies reported that good levels of physical fitness have a positive effect on physical, mental and social health in childhood and adolescence [7, 9, 46, 47].”
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Reliability of Field-Based Fitness Tests in Adults: A Systematic Review
Cuenca‐García, M., Marín‐Jiménez, N., Pérez‐Bey, A., Sánchez‐Oliva, D., Camiletti‐Moirón, D., Álvarez‐Gallardo, I. C., Ortega, F. B., & Castro‐Piñero, J. (2022) · Sports Medicine · doi:10.1007/s40279-021-01635-2 · Cited by 114
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“Several systematic reviews have found positive improvements in the physical fitness levels (i.e., MSF and CRF) of children and adolescents associated with school-based interventions [62–65].”
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“For analysis and interpretation of results, meta-analyses were conducted if at least three studies provided effect sizes for the same parameter (Garcia-Hermoso et al., 2019; Moran, RamirezCampillo & Granacher, 2018; Skrede et al., 2019).”
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“Therefore, we performed metaanalyses when ≥ 3 studies were available [2, 91].”
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“Summary Measures Meta-analyses were conducted when at least three studies provided data for physical fitness outcomes (Moran et al., 2018a; Garcia-Hermoso et al., 2019; Skrede et al., 2019).”
MethodClemente, F. M., Ramírez‐Campillo, R., Afonso, J. R., & Sarmento, H. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.642703 · Cited by 108
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“The analysis and interpretation of results in this SRMA were only conducted in the case of at least three study groups provided baseline and follow-up data for the same measure (García-Hermoso et al., 2019; Moran et al., 2018; Skrede et al., 2019).”
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MethodThe Eating Healthy and Daily Life Activities (EHDLA) Study
López‐Gil, J. F. (2022) · Children · doi:10.3390/children9030370 · Cited by 76
“, physical fitness [16,17], blood pressure [6], or sleep quality [18]).”
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“Meta-analyses were conducted when at least three studies provided enough data for effect sizes (ES) calculation (Garcia-Hermoso et al., 2019; Moran et al., 2018a; Skrede et al., 2019).”
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Clemente, F. M., Ramírez‐Campillo, R., & Sarmento, H. (2021) · Sports Medicine · doi:10.1007/s40279-020-01407-4 · Cited by 74
Field-Based Health-Related Physical Fitness Tests in Children and Adolescents: A Systematic Review
Marques, A., Henriques‐Neto, D., Peralta, M., Martins, J., Gomes, F., Popovic, S. R., Mašanović, B., Demetriou, Y., Schlund, A., & Ihle, A. (2021) · Frontiers in Pediatrics · doi:10.3389/fped.2021.640028 · Cited by 109
“Being a multi-component construct, examining PF as a whole, using only one or two tests is a misconception, as different associations between PF components and health indicators are observed (1, 45).”
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“This result is particularly important, since higher strength levels in children can be associated with higher motor proficiency (Haga, 2009 ; Wright et al., 2020 ), as well as predict a better metabolic health in adulthood (García-Hermoso et al., 2019 ).”
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Faigenbaum, A. D., MacDonald, J. P., Stracciolini, A., & Rebullido, T. R. (2020) · Current Sports Medicine Reports · doi:10.1249/jsr.0000000000000784 · Cited by 75
“Despite outdated concerns and misperceptions associated with youth resistance training, a compelling body of evidence indicates that regular participation in a well-designed resistance training program can offer observable health and fitness value for children and adolescents (12,13,63).”
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Smits-Engelsman, B. C. M., & Verbecque, E. (2021) · Biomedical Journal · doi:10.1016/j.bj.2021.08.008 · Cited by 66
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“For the analysis and interpretation of results, meta-analyses were conducted if at least three studies provided a baseline and follow-up data for the same parameter (García-Hermoso et al., 2019).”
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Contreras-Osorio, F., Ramírez‐Campillo, R., Cerda-Vega, E., Campos-Jara, R., Martínez‐Salazar, C., Reigal, R. E., Hernández-Mendo, A., Carneiro, L. S. R. D. S. F., & Campos‐Jara, C. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192215270 · Cited by 72
Fraser, B. J., Blizzard, L., Buscot, M., Schmidt, M. D., Dwyer, T., Venn, A., & Magnussen, C. G. (2021) · Journal of science and medicine in sport · doi:10.1016/j.jsams.2021.01.011 · Cited by 59
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Ramírez‐Campillo, R., Pérez‐Castilla, A., Thapa, R. K., Afonso, J. R., Clemente, F. M., Colado, J. C., de Villarreal, E. S., & Chaabène, H. (2022) · Sports Medicine - Open · doi:10.1186/s40798-022-00502-2 · Cited by 71
“Bias Although meta-analyses can be done with as few as two studies [91], because reduced sample sizes are common in the sport-science literature [92], including PJT studies [42, 65, 72, 93], meta-analysis was only conducted in the present case when ≥ 3 studies were available [76, 94].”
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“Measuring grip strength may help track changes in children’s health [12,13].”
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“Studies identifying the role of muscular fitness in metabolic control in youths with T1D are also warranted since muscular fitness seems to be positively related with lower cardiometabolic risk in children and adolescents [87].”
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Muscular Fitness and Cardiometabolic Variables in Children and Adolescents: A Systematic Review
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“Further, the impact or the heterogeneity of the results according to the tests/measurements adopted to assess muscular fitness across studies, or results described according to sex, were not considered [6, 9, 88, 89].”
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“There is a prospective association between the muscular factors, such as endurance and strength, and reduced risk of cardiometabolic parameters and adiposity, while a positive relationship is found between muscular fitness and bone health in future life [6,16].”
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“A meta-analysis for a given RSA outcome was conducted if at least three studies provided sufficient data for the calculation of ES [64, 71, 72].”
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Muscle strength and executive function in children and adolescents with autism spectrum disorder
Ludyga, S., Pühse, U., Gerber, M., & Mücke, M. (2021) · Autism Research · doi:10.1002/aur.2587 · Cited by 61
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“Previous studies indicated that obesity and low physical fitness levels in adolescence were associated with cardiovascular risks and bone health in adulthood [18,19].”
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“Maximum muscular strength, muscular power, and endurance are potentially correlated with cardiovascular variables and the future health of children and adolescents (100).”
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“Specifically, a low level of muscular fitness is recognized as a marker of poor cardiometabolic and adipose tissue function during childhood and adolescence, and also in later life [8].”
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Claudino, J. G., Afonso, J. R., Sarvestan, J., Lanza, M. B., Pennone, J., Filho, C. A. C., Serrão, J. C., Espregueira‐Mendes, J., Vasconcelos, A. L. V., de Andrade, M. P., et al. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10143184 · Cited by 53
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Effects of Olympic Combat Sports on Older Adults’ Health Status: A Systematic Review
Valdés-Badilla, P. A., Herrera-Valenzuela, T., Ramírez‐Campillo, R., Aedo–Muñoz, E., Martín, E. B.-S., Ojeda-Aravena, A., & Branco, B. H. M. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18147381 · Cited by 53
“Pre- and post-intervention means and standard deviations (SDs) for dependent variables were used after being converted to Hedges’s g effect size (ES) [28,29].”
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Ramírez‐Campillo, R., Andrade, D. C., García‐Pinillos, F., Negra, Y., Boullosa, D. A., & Moran, J. (2021) · Journal of Sports Sciences · doi:10.1080/02640414.2021.1916261 · Cited by 41
“, 2003), we conducted meta-analyses only when three or more studies provided data for the aforementioned physical fitness outcomes (Garcia-Hermoso et al., 2019; Moran et al., 2018; Skrede et al., 2019).”
MethodLópez‐Gil, J. F., Brazo‐Sayavera, J., García‐Hermoso, A., & Lucas, J. L. Y. (2020) · Nutrients · doi:10.3390/nu12020567 · Cited by 40
“Likewise, the association between PF and some metabolic risk factors in children, adolescents, and adults has been well described in previous researches [3,4].”
BackgroundRuedl, G., Niedermeier, M., Wimmer, L., Ploner, V., Pocecco, E., Cocca, A., & Greier, K. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18168736 · Cited by 49
“High physical fitness at young age is associated with reduced risk of being overweight or obese in adolescence [24] and low physical fitness in children and adolescents is associated with adiposity, lower cardiometabolic health, and lower bone health in later life [25].”
BackgroundMendonça, F. R., de Faria, W. F., da Silva, J. M., Massuto, R. B., dos Santos, G. C., Corrêa, R. C., dos Santos, C. F., Sasaki, J. E., & Neto, A. S. (2022) · Journal of Exercise Science & Fitness · doi:10.1016/j.jesf.2022.03.002 · Cited by 53
Pasanen, B. E., Tomkinson, J. M., Dufner, T. J., Park, C. W., Fitzgerald, J. S., & Tomkinson, G. R. (2021) · American Journal of Human Biology · doi:10.1002/ajhb.23657 · Cited by 38
“…measure of overall strength capacity (Bohannon et al., 2012; Wind et al., 2010), and is an important indicator of good health across the lifespan (García-Hermoso et al., 2019; McGrath et al., 2018; Ortega et al., 2012; Smith et al., 2014; Soysal et al., 2021) as well as sports/athletic…”
BackgroundBrazo‐Sayavera, J., da Silva, D. R. P., Lang, J. J., Tomkinson, G. R., Agostinis‐Sobrinho, C., Andersen, L. B., García‐Hermoso, A., Gaya, A. R., Jurak, G., Lee, E., et al. (2024) · Sports Medicine · doi:10.1007/s40279-024-02038-9 · Cited by 37
Resistance Exercise for the Prevention and Treatment of Pediatric Dynapenia
Faigenbaum, A. D., Rebullido, T. R., Peña, J., & Chulvi‐Medrano, I. (2019) · Journal of Science in Sport and Exercise · doi:10.1007/s42978-019-00038-0 · Cited by 41
May the Force Be with Youth: Foundational Strength for Lifelong Development
Faigenbaum, A. D., Ratamess, N. A., Kang, J., Bush, J. A., & Rebullido, T. R. (2023) · Current Sports Medicine Reports · doi:10.1249/jsr.0000000000001122 · Cited by 38
Cardiorespiratory and muscular fitness associations with older adolescent cognitive control
Shigeta, T. T., Leahy, A. A., Smith, J. J., Eather, N., Lubans, D. R., & Hillman, C. H. (2020) · Journal of sport and health science/Journal of Sport and Health Science · doi:10.1016/j.jshs.2020.05.004 · Cited by 39
“, muscle strength, endurance, and power) can benefit indices of health in both children and adolescents.(10,12) The benefits of physical fitness have also been extended to cognitive and brain health.”
BackgroundMuñoz‐López, A., Fonseca, F. D. S., Ramírez‐Campillo, R., Gantois, P., Nuñez, F. J., & Nakamura, F. Y. (2021) · Biology of Sport · doi:10.5114/biolsport.2021.101602 · Cited by 36
“The studies were considered as being of “excellent” (9–10 points), “good” (6–8 points), “fair” (4–5 points), or “poor” methodological quality ( ≤ 3 points)[43].”
Estevan, I., Menescardi, C., García‐Massó, X., Barnett, L. M., & Molina‐García, J. (2021) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/sms.13731 · Cited by 35
Tapia‐Serrano, M. Á., López‐Gil, J. F., Sevil‐Serrano, J., García‐Hermoso, A., & Miguel, P. A. S. (2023) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/sms.14357 · Cited by 35
Clemente, F. M., Ramírez‐Campillo, R., Afonso, J. R., Sarmento, H., Rosemann, T. J., & Knechtle, B. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18052781 · Cited by 40
Gil-Cosano, J. J., Ubago‐Guisado, E., Sánchez, M., Ortega-Acosta, M. J., Mateos, M. E., Benito, A. I., Llorente‐Cantarero, F. J., Ortega, F. B., Ruiz, J. R., Labayen, I., et al. (2020) · BMC Public Health · doi:10.1186/s12889-020-09607-3 · Cited by 33
“A recent longitudinal review showed that higher levels of muscular fitness in childhood and adolescent were associated with higher aBMD later in life [101].”
BackgroundNeuromusculoskeletal Health in Pediatric Obesity: Incorporating Evidence into Clinical Examination
O’Malley, G., Shultz, S. P., Thivel, D., & Tsiros, M. D. (2021) · Current Obesity Reports · doi:10.1007/s13679-021-00463-9 · Cited by 36
López‐Gil, J. F., Brazo‐Sayavera, J., Lucas, J. L. Y., & Cavichiolli, F. R. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17124518 · Cited by 35
“Moreover, some studies have reported a negative association between excess body fat and some parameters of health-related PF, such as CRF [9,10] or muscular fitness [11,12].”
BackgroundThapa, R. K., Narvariya, P., Weldon, A., Talukdar, K., & Ramírez‐Campillo, R. (2022) · Montenegrin Journal of Sports Science and Medicine · doi:10.26773/mjssm.220906 · Cited by 32
Carneiro, L., Afonso, J., Ramirez-Campillo, R., Murawska-Ciałowciz, E., Marques, A., & Clemente, F. M. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17186715 · Cited by 31
“The analysis and interpretation of results in this SRMA were only conducted if at least three study groups provided baseline and follow-up data for the same measure [41].”
Methodda Silva, P. R., dos Santos, G. C., da Silva, J. M., de Faria, W. F., de Oliveira, R. G., & Neto, A. S. (2020) · Journal of Exercise Science & Fitness · doi:10.1016/j.jesf.2020.06.002 · Cited by 30
Béghin, L., Thivel, D., Baudelet, J., Deschamps, T., Ovigneur, H., & Vanhelst, J. (2022) · European Journal of Pediatrics · doi:10.1007/s00431-022-04610-9 · Cited by 30
“The authors showed that low muscular strength and CRF in adolescence are strongly associated with risk factors for major causes of death in adulthood [4, 5].”
BackgroundInfluentialBack pain in children and adolescents: a cross-sectional study
Azevedo, N., Ribeiro, J. C., & Machado, L. J. (2023) · European Spine Journal · doi:10.1007/s00586-023-07751-z · Cited by 30
Normative health‐related fitness values for French children: The Diagnoform Programme
Vanhelst, J., Ternynck, C., Ovigneur, H., & Deschamps, T. (2019) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/sms.13607 · Cited by 29
García-Carrillo, E., Ramírez‐Campillo, R., Thapa, R. K., Afonso, J. R., Granacher, U., & Izquierdo, M. (2023) · Sports Medicine - Open · doi:10.1186/s40798-023-00631-2 · Cited by 41
“However, meta-analyses were performed if ≥ 3 studies were available due to the reduced number of participants commonly included in plyometric training studies [65–67].”
MethodReis, L. N., Reuter, C. P., Burns, R. D., Martins, C., Mota, J. A. P. S., Gaya, A. C. A., Silveira, J. F. D. C., & Gaya, A. R. (2024) · BMC Pediatrics · doi:10.1186/s12887-024-04544-1 · Cited by 42
Reščič, N., Alberts, J. W., Altenburg, T. M., Chinapaw, M. J. M., Nigro, A. D., Fenoglio, D., Gjoreski, M., Gradišek, A., Jurak, G., Kiourtis, A., et al. (2023) · International Conference on Applied Mathematics & Computer Science (ICAMCS) · doi:10.1109/icamcs59110.2023.00020 · Cited by 28
“These risk factors often occur together and can interact to increase the risk of NCDs. Adopting a healthy lifestyle can enhance physical, social, and mental well-being, particularly among young individuals, while minimising the risks of morbidity and mortality associated with NCDs, [2], [3], [4].”
BackgroundSmits-Engelsman, B. C. M., Bonney, E., Neto, J. L. C., & Jelsma, D. (2020) · BMC Public Health · doi:10.1186/s12889-020-09236-w · Cited by 28
Longitudinal associations of physical fitness and body mass index with academic performance
García‐Hermoso, A., Martínez‐Gómez, D., Fernández‐Santos, J. R., Ortega, F. B., Castro‐Piñero, J., Hillman, C. H., Veiga, Ó. L., & Esteban‐Cornejo, I. (2020) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/sms.13817 · Cited by 28
Noll, M. A., Wedderkopp, N., Mendonça, C. R., & Kjær, P. (2020) · Systematic Reviews · doi:10.1186/s13643-020-01468-6 · Cited by 29
“Motor performance components are essential to psychological and social development in children and adolescents [26] and have been recognized as an important determinant of current and future health status [27, 28].”
BackgroundRamírez‐Campillo, R., García‐Pinillos, F., Nikolaidis, P. Τ., Clemente, F. M., Gentil, P., & García‐Hermoso, A. (2021) · Biology of Sport · doi:10.5114/biolsport.2022.104916 · Cited by 32
“For analysis and interpretation of results, meta-analyses were conducted if at least three studies provided effect sizes for the same parameter [29, 34, 35].”
MethodSun, Y., Yu, S., Wang, A., Chan, H. C.-K., Ou, A. Y. T., Zhang, D., Xie, Y. J., Fong, S. S. M., & Gao, Y. (2022) · Scientific Reports · doi:10.1038/s41598-022-26024-1 · Cited by 26
The epidemiology of muscle-strengthening activity among adolescents from 28 European countries
Bennie, J. A., Faulkner, G., & Smith, J. J. (2021) · Scandinavian Journal of Public Health · doi:10.1177/14034948211031392 · Cited by 31
“[8] García-hermoso A, ramírez-Campillo r and Izquierdo M.”
Radulović, A., Jurak, G., Leskošek, B., Starc, G., & Blagus, R. (2022) · Scientific Reports · doi:10.1038/s41598-022-14813-7 · Cited by 26
Singh, U., Ramachandran, A. K., Ramírez‐Campillo, R., Pérez‐Castilla, A., Afonso, J. R., Clemente, F. M., & Oliver, J. L. (2022) · Journal of Sports Sciences · doi:10.1080/02640414.2022.2099161 · Cited by 30
“The ability to carry out daily tasks and perform physical activities in a highly functional state (i.e., physical fitness) is an important marker of current and future health status (Cadenas-Sanchez et al., 2021; Garcia-Hermoso et al., 2019).”
BackgroundInfluentialFeasibility and Reliability of Physical Fitness Tests among Colombian Preschool Children
Amado-Pacheco, J., Prieto‐Benavides, D. H., Correa‐Bautista, J. E., García‐Hermoso, A., Agostinis‐Sobrinho, C., Alonso-Martínez, A. M., Izquierdo, M., & Ramírez‐Vélez, R. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16173069 · Cited by 24
Guillem, C. M., Loaiza-Betancur, A. F., Rebullido, T. R., Faigenbaum, A. D., & Chulvi‐Medrano, I. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17217900 · Cited by 28
“RT is an evidence-based preventative exercise intervention strategy that can promote health and well-being through the life course [37,38].”
BackgroundEpidemiology of Sports-Related Clavicle Fractures in the United States: Injuries From 2015 to 2019
Twomey-Kozak, J. N., Whitlock, K. G., O’Donnell, J. A., Klifto, C. S., & Anakwenze, O. A. (2022) · Orthopaedic Journal of Sports Medicine · doi:10.1177/23259671221126553 · Cited by 25
Metadata
- Authors
- García-Hermoso, A., Ramírez-Campillo, R., & Izquierdo, M.
- Venue
- Sports Medicine
- Published
- 2019-04-05
- Volume
- 49
- Issue
- 7
- Pages
- 1079-1094
- ISSN
- 0112-1642 (ISSN-L)
- 1179-2035
- OpenAlex
- W2935554824
- Cited by
- 512
- References
- 82
- Citations by year
- 2026: 45 · 2025: 56 · 2024: 81 · 2023: 75 · 2022: 90 · 2021: 93 · 2020: 57 · 2019: 14
- FWCI
- 7.46
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Sports Medicine (publishedVersion)
- PubMed (publishedVersion)
- Academica-e (Universidad Pública de Navarra) (acceptedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Social Sciences › Psychology › Developmental and Educational Psychology › Children's Physical and Motor Development
- Keywords
- muscular fitness, childhood, adolescence, body mass index, adiposity, cardiometabolic health, insulin resistance, triglycerides, cardiovascular risk, bone mineral density, musculoskeletal health, low back pain, grip strength, sit-ups, standing long jump, skinfold thickness
- MeSH terms
- Adolescent, Anthropometry, Child, Health Status, Humans, Physical Fitness, Bone Density, Body Mass Index, Adiposity, Muscle Strength
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