A survey on differential privacy for medical data analysis
Open accessAbstract
Machine learning methods promote the sustainable development of wise information technology of medicine (WITMED), and a variety of medical data brings high value and convenience to medical analysis. However, the applications of medical data have also been confronted with the risk of privacy leakage that is hard to avoid, especially when conducting correlation analysis or data sharing among multiple institutions. Data security and privacy preservation have recently played an essential role in the field of secure and private medical data analysis, where many differential privacy strategies are applied to medical data publishing and mining. In this paper, we survey research work on the applications of differential privacy for medical data analysis, discussing the necessity of medical privacy-preserving, the advantages of differential privacy, and their applications to typical medical data, such as genomic data and wearable device data. Furthermore, we discuss the challenges and potential future research directions for differential privacy in medical applications.
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Both privacy and security are popular topics of research and several approaches have been proposed including anonymity frameworks, differential privacy, and blockchain-based solutions.
“Both privacy and security are popular topics of research and several approaches have been proposed including anonymity frameworks [203] to more recently proposed differential privacy [204], and blockchain-based solutions [205].”
From Human-centred artificial intelligence for mobile health sensing: challenges and opportunities (2023) · cites this paper as [204]
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Odeyomi, O. T., Karnati, H., & Smith, A. C. (2024) · IEEE World AI IoT Congress (AIIoT) · doi:10.1109/aiiot61789.2024.10578985 · Cited by 3 · see citing works
Distributed empirical likelihood inference with privacy guarantees
Liu, Q., & Li, Z. (2025) · Statistics and Computing · doi:10.1007/s11222-025-10614-w · Cited by 2 · see citing works
Frequency estimation under relaxed input-discriminative local differential privacy
Kuang, X., Zhu, Y., Liu, R., & Zhang, S. (2025) · Information Sciences · doi:10.1016/j.ins.2025.122351 · Cited by 2 · see citing works
Elkomy, O. M., Rushdy, E., Nasser, S., & Khashaba, M. M. (2025) · Journal Of Big Data · doi:10.1186/s40537-025-01292-6 · Cited by 2 · see citing works
The role of Anonymization Techniques in Differential Privacy
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Differentially Private Selection using Smooth Sensitivity
Yamamoto, A., & Shibuya, T. (2024) · IEEE International Performance, Computing, and Communications Conference · doi:10.1109/ipccc59868.2024.10850477 · Cited by 2 · see citing works
Challenges and future directions of AIRR-seq-based diagnostics
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Yamamoto, A., & Shibuya, T. (2025) · Lecture notes in computer science · doi:10.1007/978-981-96-9101-2_4 · Cited by 1 · see citing works
Cryptographic Commitments on Anonymizable Data
Bultel, X., Chevalier, C., Jojon, C., Liu, D., & Nguyen, B. (2025) · IEEE European Symposium on Security and Privacy · doi:10.1109/eurosp63326.2025.00037 · Cited by 1 · see citing works
Artificial Intelligence (AI) in Patient–Healthcare Relationships: Psychosocial Perspective
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Between Privacy and Utility: Navigating Inference Risks in De-Identified Health Data
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Rimi, H. A., Asaduzzaman, M., Bhuiyan, M. J. U., Shoaib, H. A., Fuad, K. M. N. R., & Rahman, M. A. (2025) · Studies in computational intelligence · doi:10.1007/978-981-96-8353-6_11 · Cited by 2 · see citing works
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Cybersecurity Challenges, Best Practices, and Future Work in Healthcare
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Privacy-Preserving Clustering via Selective Knowledge Distillation
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Blockchain Enabled EHR Sharing with Zero-Trust Access Controls and Differential Privacy Protection
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- Authors
- Liu, W., Zhang, Y., Yang, H., & Meng, Q.
- Affiliations
- Guangzhou University (CN)
- Suzhou University (CN)
- Corresponding author
- Liu, WeiKang
- Venue
- Annals of Data Science
- Published
- 2023-06-10
- Volume
- 11
- Issue
- 2
- Pages
- 733-747
- ISSN
- 2198-5804 (ISSN-L)
- 2198-5812
- PMC
- PMC10257172
- OpenAlex
- W4380151986
- Cited by
- 66
- References
- 71
- Citations by year
- 2026: 16 · 2025: 39 · 2024: 10 · 2023: 1
- FWCI
- 1.38
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Annals of Data Science (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Topics
- Physical Sciences › Computer Science › Artificial Intelligence › Privacy-Preserving Technologies in Data
- Physical Sciences › Computer Science › Information Systems › Cloud Data Security Solutions
- Physical Sciences › Computer Science › Information Systems › Thoreau and American Literature
- Keywords
- differential privacy, medical data privacy, privacy-preserving data mining, genomic data, wearable device data, privacy leakage
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