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Anti-fouling Coatings of Poly(dimethylsiloxane) Devices for Biological and Biomedical Applications
Open accessAbstract
Fouling initiated by nonspecific protein adsorption is a great challenge in biomedical applications, including biosensors, bioanalytical devices, and implants. Poly(dimethylsiloxane) (PDMS), a popular material with many attractive properties for device fabrication in the biomedical field, suffers serious fouling problems from protein adsorption due to its hydrophobic nature, which limits the practical use of PDMS-based devices. Effort has been made to develop biocompatible materials for anti-fouling coatings of PDMS. In this review, typical nonfouling materials for PDMS coatings are introduced and the associated basic anti-fouling mechanisms, including the steric repulsion mechanism and the hydration layer mechanism, are described. Understanding the relationships between the characteristics of coating materials and the accompanying anti-fouling mechanisms is critical for preparing PDMS coatings with desirable anti-fouling properties.
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Citations
Cited by
Yang, J. C., Mun, J., Kwon, S. Y., Park, S., Bao, Z., & Park, S. (2019) · Advanced Materials · doi:10.1002/adma.201904765 · Cited by 1,641
PDMS with designer functionalities—Properties, modifications strategies, and applications
Wolf, M. P., Salieb-Beugelaar, G. B., & Hunziker, P. (2018) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2018.06.001 · Cited by 853
An introduction to zwitterionic polymer behavior and applications in solution and at surfaces
Blackman, L. D., Gunatillake, P. A., Cass, P., & Locock, K. E. S. (2019) · Chemical Society Reviews · doi:10.1039/c8cs00508g · Cited by 502
Poly(2-oxazoline)s based biomaterials: a comprehensive and critical update
Lorson, T., Lübtow, M. M., Wegener, E., Haider, M. S., Borova, S., Nahm, D., Jordan, R., Sokolski-Papkov, M., Kabanov, A. V., & Luxenhofer, R. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.05.022 · Cited by 391
A Materials Roadmap to Functional Neural Interface Design
Wellman, S. M., Eles, J. R., Ludwig, K. A., Seymour, J. P., Michelson, N. J., McFadden, W. E., Vazquez, A. L., & Kozai, T. D. Y. (2018) · Advanced Functional Materials · doi:10.1002/adfm.201701269 · Cited by 389
Metadata
- Authors
- Zhang, H., & Chiao, M.
- Venue
- Journal of Medical and Biological Engineering
- Published
- 2015-04
- Volume
- 35
- Issue
- 2
- Pages
- 143-155
- ISSN
- 1609-0985 (ISSN-L)
- 2199-4757
- OpenAlex
- W289241723
- Cited by
- 415
- References
- 0
- FWCI
- 13.72
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Zhang, H., & Chiao, M. (2015). Anti-fouling Coatings of Poly(dimethylsiloxane) Devices for Biological and Biomedical Applications. Journal of Medical and Biological Engineering. https://doi.org/10.1007/s40846-015-0029-4
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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