The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Stability over time of variables measuring heart rate variability in normal subjects
Open accessAbstract
Both time and frequency domain measures of heart rate (HR) variability have been used to assess autonomic tone in a variety of clinical conditions. Few studies in normal subjects have been performed to determine the stability of HR variability over time, or the correlation between and within time and frequency domain measures of HR variability. Fourteen normal subjects aged 20 to 55 years were studied with baseline and placebo 24-hour ambulatory electrocardiograms performed 3 to 65 days apart to assess the reproducibility of the following time domain measures of cycle length variability: the standard deviation of all normal cycle intervals; mean normal cycle interval; mean day normal cycle interval; night/day difference in mean normal cycle interval; root-mean-square successive cycle interval difference; percentage of differences between adjacent normal cycle length intervals that are greater than 50 ms computed over the entire 24-hour electrocardiographic recording (proportion of adjacent intervals greater than 50 ms); and the frequency domain measures of high (0.15 to 40 Hz), low (0.003 to 0.15) and total (0.003 to 0.40) power. The mean and standard deviations of these measures were virtually identical between placebo and baseline measurements and within the studied time range. Variables strongly dependent on vagal tone (high-frequency, low-frequency and total power, root-mean-square successive difference, and percentage of differences between adjacent normal cycle intervals greater than 50 ms computed over the entire 24-hour electrocardiographic recording) were highly correlated (r greater than 0.8). It is concluded that measures of HR variability are stable over short periods of time.(ABSTRACT TRUNCATED AT 250 WORDS)
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Cites
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Heart Rate Variability: Standards of Measurement, Physiological Interpretation, and Clinical Use
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Heart rate variability: Standards of measurement, physiological interpretation, and clinical use
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Self-citationHeart rate variability: A review
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Metadata
- Authors
- Kleiger, R. E., Bigger, J. T., Bosner, M. S., Chung, M. K., Cook, J. R., Rolnitzky, L. M., Steinman, R., & Fleiss, J. L.
- Venue
- The American Journal of Cardiology
- Publisher
- Elsevier BV
- Published
- 1991-09
- Volume
- 68
- Issue
- 6
- Pages
- 626-630
- ISSN
- 0002-9149 (ISSN-L)
- OpenAlex
- W2024177262
- Cited by
- 390
- References
- 22
- FWCI
- 9.52
- Type
- journal article
- Language
- en
- Open access
- hybrid
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