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Cited by 244Cardiovascular Health and Risk FactorsLipoproteins and Cardiovascular HealthDiabetes, Cardiovascular Risks, and Lipoproteins

The DOI matches its Crossref record; 27 of the 28 references it cites were found in a registry or an index.

Prevalence of risk factors in men with premature coronary artery disease

Genest, Jacques J., McNamara, Judith R., Salem, Deeb N., Schaefer, Ernst J.·1991·The American Journal of Cardiology
DOI 10.1016/0002-9149(91)90924-a
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Abstract

The prevalence of modifiable cardiovascular risk factors (systemic hypertension, diabetes mellitus, cigarette smoking, low-density lipoprotein [LDL] cholesterol greater than or equal to 160 mg/dl and high-density lipoprotein [HDL] cholesterol less than 35 mg/dl) was determined in 321 men less than 60 years of age (mean +/- standard deviation 50 +/- 7) with premature coronary artery disease (CAD) documented at coronary angiography. The prevalence of these risk factors was markedly different than in the Framingham Offspring Study population, used here as a comparison group. In the patients with CAD, only 3% had no risk factor (other than male sex), compared with 31% in the Framingham Offspring Study subjects. Most patients with CAD (97%) had greater than or equal to 1 additional risk factor. When the patients with CAD were divided by age groups (40 to 49 years [n = 109], 50 to 59 [n = 191]), no significant differences were observed in the prevalence of risk factors between the young and older patients. The prevalence of systemic hypertension (41 vs 19%, p less than 0.001), diabetes mellitus (12 vs 1.1%, p less than 0.001), cigarette smoking (67 vs 28%, p less than 0.001) and HDL cholesterol less than 35 mg/dl (63 vs 19%, p less than 0.001) was markedly higher in the patients with CAD than in Framingham Offspring Study subjects, whereas the prevalence of LDL cholesterol greater than or equal to 160 mg/dl was not significantly different between patients with CAD and Framingham Offspring Study subjects (26 vs 26%).(ABSTRACT TRUNCATED AT 250 WORDS)

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Crossref · 10.1016/0002-9149(91)90924-a

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Research works printed but not linked: 2

  1. 1988, Can Med Assoc J, 138, 1
  2. Warnick, 1982, Dextran sulfate-Mg2+ precipitation procedure for quantitation of high-density lipoprotein cholesterol, Clin Chem, 79, 93

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Metadata

Authors
Genest, J. J., McNamara, J. R., Salem, D. N., & Schaefer, E. J.
Affiliations
Tufts University (US)
Corresponding author
Schaefer, Ernst J.
ORCID
Venue
The American Journal of Cardiology
Publisher
Elsevier BV
Published
1991-06
Volume
67
Issue
15
Pages
1185-1189
ISSN
0002-9149 (ISSN-L)
DOI
10.1016/0002-9149(91)90924-a
OpenAlex
W2041225533
Cited by
243
References
28
Citations by year
2023: 2 · 2022: 4 · 2021: 2 · 2020: 3 · 2019: 1 · 2018: 8 · 2017: 5 · 2016: 4 · 2015: 5 · 2014: 9 · 2013: 6 · 2012: 10
FWCI
4.38
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • The American Journal of Cardiology (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (5r01hl035243-03)
  • National Heart, Lung, and Blood Institute (HL 35243)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords
premature coronary artery disease, cardiovascular risk factors, men, systemic hypertension, diabetes mellitus, cigarette smoking, LDL cholesterol, HDL cholesterol, beta-blockers, Framingham Offspring Study, National Cholesterol Education Program guidelines, triglycerides, coronary angiography, young adults, risk factor prevalence
MeSH terms
Adult, Coronary Disease, Diabetes Mellitus, Humans, Hypertension, Cholesterol, HDL, Cholesterol, LDL, Male, Massachusetts, Middle Aged, Risk Factors, Smoking, Prevalence

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