CoChat
Sign Up
Cited by 244Cardiovascular Health and Risk FactorsLipoproteins and Cardiovascular HealthDiabetes, Cardiovascular Risks, and Lipoproteins

The DOI matches its Crossref record; 27 of the 28 references it cites were found in a registry or an index.

Prevalence of risk factors in men with premature coronary artery disease

Genest, Jacques J., McNamara, Judith R., Salem, Deeb N., Schaefer, Ernst J.·1991·The American Journal of Cardiology
DOI 10.1016/0002-9149(91)90924-a
Open this paper in CoChat — free account

Abstract

The prevalence of modifiable cardiovascular risk factors (systemic hypertension, diabetes mellitus, cigarette smoking, low-density lipoprotein [LDL] cholesterol greater than or equal to 160 mg/dl and high-density lipoprotein [HDL] cholesterol less than 35 mg/dl) was determined in 321 men less than 60 years of age (mean +/- standard deviation 50 +/- 7) with premature coronary artery disease (CAD) documented at coronary angiography. The prevalence of these risk factors was markedly different than in the Framingham Offspring Study population, used here as a comparison group. In the patients with CAD, only 3% had no risk factor (other than male sex), compared with 31% in the Framingham Offspring Study subjects. Most patients with CAD (97%) had greater than or equal to 1 additional risk factor. When the patients with CAD were divided by age groups (40 to 49 years [n = 109], 50 to 59 [n = 191]), no significant differences were observed in the prevalence of risk factors between the young and older patients. The prevalence of systemic hypertension (41 vs 19%, p less than 0.001), diabetes mellitus (12 vs 1.1%, p less than 0.001), cigarette smoking (67 vs 28%, p less than 0.001) and HDL cholesterol less than 35 mg/dl (63 vs 19%, p less than 0.001) was markedly higher in the patients with CAD than in Framingham Offspring Study subjects, whereas the prevalence of LDL cholesterol greater than or equal to 160 mg/dl was not significantly different between patients with CAD and Framingham Offspring Study subjects (26 vs 26%).(ABSTRACT TRUNCATED AT 250 WORDS)

Overview

Integrity signals

Registry

Crossref · 10.1016/0002-9149(91)90924-a

Cites

27 of 27 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 28 references

Research works printed but not linked: 2

  1. 1988, Can Med Assoc J, 138, 1
  2. Warnick, 1982, Dextran sulfate-Mg2+ precipitation procedure for quantitation of high-density lipoprotein cholesterol, Clin Chem, 79, 93

Cited by

Sorted by citations

Items 201–244 of 244

Related

See all

Metadata

Authors
Genest, J. J., McNamara, J. R., Salem, D. N., & Schaefer, E. J.
Affiliations
Tufts University (US)
Corresponding author
Schaefer, Ernst J.
ORCID
Venue
The American Journal of Cardiology
Publisher
Elsevier BV
Published
1991-06
Volume
67
Issue
15
Pages
1185-1189
ISSN
0002-9149 (ISSN-L)
DOI
10.1016/0002-9149(91)90924-a
OpenAlex
W2041225533
Cited by
243
References
28
Citations by year
2023: 2 · 2022: 4 · 2021: 2 · 2020: 3 · 2019: 1 · 2018: 8 · 2017: 5 · 2016: 4 · 2015: 5 · 2014: 9 · 2013: 6 · 2012: 10
FWCI
4.38
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • The American Journal of Cardiology (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (5r01hl035243-03)
  • National Heart, Lung, and Blood Institute (HL 35243)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords
premature coronary artery disease, cardiovascular risk factors, men, systemic hypertension, diabetes mellitus, cigarette smoking, LDL cholesterol, HDL cholesterol, beta-blockers, Framingham Offspring Study, National Cholesterol Education Program guidelines, triglycerides, coronary angiography, young adults, risk factor prevalence
MeSH terms
Adult, Coronary Disease, Diabetes Mellitus, Humans, Hypertension, Cholesterol, HDL, Cholesterol, LDL, Male, Massachusetts, Middle Aged, Risk Factors, Smoking, Prevalence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review