The DOI matches its Crossref record; 29 of the 31 references it cites were found in a registry or an index.
Vascular endothelium: an integrator of pathophysiologic stimuli in atherosclerosis.
Abstract
Vascular endothelium, the single-cell-thick lining of the cardiovascular system, is an important functional component of the blood vessel wall, actively participating in normal vascular physiology as well as the pathogenesis of vascular diseases such as atherosclerosis. The localized modulation of vascular endothelium to a non-adaptive functional state can be termed "endothelial dysfunction." This article provides a brief overview of endothelial dysfunction, especially as it relates to mononuclear leukocyte recruitment during atherosclerotic lesion formation. Potential diagnostic and therapeutic implications are also considered.
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“In vitro studies have implicated these lipids (and in some experiments lipolysis of triglyceride) in inflammation (147), expression of adhesion molecules (148), and promotion of coagulation (149).”
From Evaluation and Treatment of Hypertriglyceridemia: An Endocrine Society Clinical Practice Guideline (2012) · cites this paper as [148]
Citations
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Metadata
- Authors
- Gimbrone, M. A.
- Affiliations
- Brigham and Women's Hospital (US)
- Corresponding author
- Gimbrone, Michael A.
- Venue
- The American Journal of Cardiology
- Publisher
- Elsevier BV
- Published
- 1995-02
- Volume
- 75
- Issue
- 6
- Pages
- 67B-70B
- ISSN
- 0002-9149 (ISSN-L)
- OpenAlex
- W2045786338
- Cited by
- 225
- References
- 31
- Citations by year
- 2026: 3 · 2024: 2 · 2023: 3 · 2022: 1 · 2021: 7 · 2020: 7 · 2019: 6 · 2018: 7 · 2017: 11 · 2016: 12 · 2015: 7 · 2014: 5 · 2013: 8 · 2012: 9
- FWCI
- 1.38
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The American Journal of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
- Life Sciences › Immunology and Microbiology › Immunology › Atherosclerosis and Cardiovascular Diseases
- Health Sciences › Medicine › Immunology and Allergy › Cell Adhesion Molecules Research
- Keywords
- vascular endothelium, endothelial dysfunction, atherosclerosis, atherosclerotic lesion formation, vascular physiology, vascular disease pathogenesis
- MeSH terms
- Animals, Arteriosclerosis, Endothelium, Vascular, Humans, Leukocytes, Mononuclear, Cell Adhesion Molecules, Vascular Cell Adhesion Molecule-1
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