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Cited by 17Maternal and Perinatal Health InterventionsMaternal and fetal healthcarePreterm Birth and Chorioamnionitis

Intranasal oxytocin in eighteen hundred patients

Hoover, Robert T.·1971·American Journal of Obstetrics and Gynecology
DOI 10.1016/0002-9378(71)90576-x
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  • In Hoover's study of 1,806 women, intranasal oxytocin augmented labor at 1-4 doses of 0.4-0.8 IU every 20 minutes (maximum 3.2 IU); equivalent effects from intravenous infusion of 1-2 mU/min led to an estimate that about 1% of intranasally applied oxytocin enters the circulation.

    “Hoover studied 1,806 women who had been given intranasal oxytocin during childbirth (31).Labor was stimulated by 1-4 doses of 0.4-0.8IUgiven at 20-min intervals -a total of, at most, 3.2IU.Equivalent effects were achieved by intravenous infusion of 1-2mU/min, giving rise to the estimate that ~1% of intranasally-applied oxytocin enters the circulation (32).”

    From Intranasal Oxytocin: Myths and Delusions (2016) · cites this paper as [31]

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Authors
Hoover, R. T.
Affiliations
AdventHealth (US)
Corresponding author
Hoover, Robert T.
Venue
American Journal of Obstetrics and Gynecology
Publisher
Elsevier BV
Published
1971-07
Volume
110
Issue
6
Pages
788-794
ISSN
0002-9378 (ISSN-L)
DOI
10.1016/0002-9378(71)90576-x
OpenAlex
W2370738225
Cited by
17
References
4
Citations by year
2023: 1 · 2022: 1 · 2021: 1 · 2018: 1 · 2017: 1 · 2015: 1 · 2013: 2
FWCI
0.00
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • American Journal of Obstetrics and Gynecology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Obstetrics and Gynecology › Maternal and Perinatal Health Interventions
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Maternal and fetal healthcare
  • Health Sciences › Medicine › Epidemiology › Preterm Birth and Chorioamnionitis
Keywords
intranasal oxytocin, labor induction, cesarean section rate, maternal complications, cervical laceration, fetal death, neonatal depression, uterine inversion
MeSH terms
Aerosols, Apgar Score, Female, Fetal Death, Fetal Diseases, Hospitals, General, Humans, Infant, Newborn, Labor, Induced, Methods, Oxytocin, Parity, Pregnancy, Pregnancy Complications, Retrospective Studies, Solutions

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