The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Preeclampsia and antioxidant nutrients: Decreased plasma levels of reduced ascorbic acid, α-tocopherol, and beta-carotene in women with preeclampsia
Abstract
Objective Our purpose was to investigate the plasma levels of three potent antioxidant nutrients in women with preeclampsia. Study design Fasting venous blood samples were collected from 30 women with preeclampsia and from 44 women with uncomplicated pregnancies. The criteria for recruitment included age 15 to 35 years, gestational age 28 to 42 weeks, singleton pregnancy, intact membranes, absence of labor contractions, and absence of any other medical complication concurrent with preeclampsia. Reduced ascorbic acid, alpha-tocopherol, and beta-carotene levels were assayed with high-pressure liquid chromatography. Results Plasma levels of reduced ascorbic acid were significantly decreased in patients with mild and severe preeclampsia (p Conclusion In patients with preeclampsia antioxidant nutrients may be utilized to a greater extent to counteract free radical-mediated cell disturbances, resulting in a reduction in antioxidant plasma levels. Water-soluble antioxidant nutrients may initially be consumed, followed by lipid-soluble antioxidants.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“In patients with preeclampsia, antioxidant nutrient levels as well as antioxidant response was lower while lipid peroxidation was higher (Takagi et al, 2004;Aydin et al, 2004 andMikhail et al, 1994).”
From Iron, Oxidative Stress and Health (2012) · cites this paper as Mikhail et al, 1994
Citations
Cites
Ascorbate is an outstanding antioxidant in human blood plasma
Frei, B., England, L., & Ames, B. N. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.16.6377 · Cited by 1,870
Preeclampsia: an endothelial cell disorder
Roberts, J. M., Taylor, R. N., Musci, T. J., Rodgers, G. M., Hubel, C. A., & McLaughlin, M. K. (1989) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(89)90665-0 · Cited by 1,859
Antioxidant defense systems: the role of carotenoids, tocopherols, and thiols
Mascio, P. D., Murphy, M., & Sies, H. (1991) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/53.1.194s · Cited by 776
Absorption, lipoprotein transport, and regulation of plasma concentrations of vitamin E in humans.
Kayden, H. J., & Traber, M. G. (1993) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)40727-8 · Cited by 584
yw, A. L., Michalak, J., Stępień, A., & Kadziołka, A. (1986) · Clinica Chimica Acta · doi:10.1016/0009-8981(86)90247-0 · Cited by 520
Lipid peroxidation in pregnancy: New perspectives on preeclampsia
Hubel, C. A., Roberts, J. M., Taylor, R. N., Musci, T. J., Rogers, G. M., & McLaughlin, M. K. (1989) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(89)90778-3 · Cited by 445
Wefers, H., & Sies, H. (1988) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1988.tb14105.x · Cited by 389
Roberts, J. M., Taylor, R. N., & Goldfien, A. (1991) · American Journal of Hypertension · doi:10.1093/ajh/4.8.700 · Cited by 389
Halliwell, B. B. (1989) · PubMed Central · Cited by 366
Antioxidant nutrients and disease prevention: an overview
Diplock, A. T. (1991) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/53.1.189sb · Cited by 337
Research works printed but not linked: 1
- American College of Obstetricians and Gynecologists. Management of Preeclampsia. Washington, DC: American College of Obstetricians and Gynecologists, 1986. (Technical bulletin no 91).
Cited by
Sorted by citations
Items 201–229 of 229
The Use of Antioxidants in Pre-eclampsia
Bilodeau, J. (2012) · Humana Press eBooks · doi:10.1007/978-1-62703-041-0_6 · Cited by 1
Hypertensive Schwangerschaftserkrankungen
Dürig, P. (2004) · Springer eBooks · doi:10.1007/978-3-642-18574-8_18 · Cited by 1
Al-Azzawie, H. F., & Humadi, E. H. (2014) · Jordan Medical Journal · Cited by 1
Hypertensive Schwangerschaftserkrankungen
Raio, L., Baumann, M. U., & Schneider, H. (2016) · Springer eBooks · doi:10.1007/978-3-662-45064-2_22 · Cited by 1
Tolcher, M. C., Figueroa, H. M., & Aagaard, K. M. (2018) · doi:10.1002/9781119129400.ch50 · Cited by 1
Complications of Pre‐eclampsia
Dildy, G. A., & Belfort, M. A. (2010) · doi:10.1002/9781444316780.ch34 · Cited by 1
Hypertensive Schwangerschaftserkrankungen
Dürig, P. (2000) · Springer eBooks · doi:10.1007/978-3-642-98004-6_18 · Cited by 1
Kaur, R. (2014) · Andrology & Gynecology Current Research · doi:10.4172/2327-4360.1000117
Jahan, K., Parvin, M., & Mafiz, A. I. (2013) · Bangladesh Journal of Nutrition · doi:10.3329/bjnut.v24i0.14032
Relationship of serum ceruloplasmin and pre-eclampsia
moghadam, T. G., Moslemizadeh, N., Mohammadpour, R. A., & Robati, M. H. (2008) · DOAJ (DOAJ: Directory of Open Access Journals)
Vainio, M. (2003) · Tampere University Institutional Repository (Tampere University)
Acute atherosis and oxidative stressin preeclampsia
Harsem, N. K. (2008) · NORA - Norwegian Open Research Archives
ARTIGOS ORIGINAIS / ORIGINAL ARTICLES
Nalepa, K. C., & Ferreira, S. M. R. (2013)
Prevention of Pre-eclampsia: Low-dose Aspirin, Calcium and Antioxidants
Gratton, R. J., & Roberts, J. M. (1999) · Journal SOGC · doi:10.1016/s0849-5831(16)31076-x
Vitamin E Metabolism in the Fetus and Newborn Infant
Johnson, L. H., & Bhutani, V. K. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4160-3479-7.10039-4
VITAMIN A, CAROTENOIDS, AND HIV INFECTION
Friis, H. (2001) · CRC Press eBooks · doi:10.1201/9781420042351-7
Abdalvand, A. (2012) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r3pt57
Lupus Nephritis Presenting with Preeclampsia
Eroğlu, E., Çetın, M., Kocyigit, I. D., Akgün, H., Sipahioğlu, M. H., Tokgöz, B., & Oymak, O. (2020) · Turkish Journal of Nephrology · doi:10.5152/turkjnephrol.2020.3579
To Estimate Trace Elements, Oxidative Stress and Antioxidant during Preeclampsia and Eclampsia
Rajdev, S., Agarwal, B. K., & Nigoskar, S. (2020) · Scholars International Journal of Biochemistry · doi:10.36348/sijb.2020.v03i12.003
Vitamin a, Carotenoids, and Hiv Infection
Semba, R. D. (2001) · Modern nutrition · doi:10.1201/9781420042351.ch4
Hypertensive Schwangerschaftserkrankungen
Raio, L., Baumann, M. U., & Schneider, H. (2011) · Springer eBooks · doi:10.1007/978-3-642-12974-2_17
Rojekar, M. V., Dandegonker, K. S., & Ghanghurde, S. (2023) · IntechOpen eBooks · doi:10.5772/intechopen.110843
Fallah, S., Karimian, Z., Behjati, M., Ebadifar, R., Motlagh, Z. H., & Vahedpour, Z. (2024) · Human Gene · doi:10.1016/j.humgen.2024.201294
Maternal Mortality in Developing Countries
Ronsmans, C. (2001) · Humana Press eBooks · doi:10.1007/978-1-59259-225-8_2
Differential Plasma Carotenoid Profiles in Hypertensive Disorders of Pregnancy
Freel, C., Scheffler, J., Slotkowski, R., Lyden, E. R., VanOrmer, M., Thoene, M. K., Mishra, P. K., Hanson, C., & Anderson‐Berry, A. (2025) · Nutrients · doi:10.3390/nu17193104
Identifying biomarkers of the serum proteins and metabolites associated with severe preeclampsia
Liu, X., Lu, T., Zeng, X., Hu, Y., Xin, S., Chen, Y., Hu, Z., Yu, M., Zou, Y., & Xiong, X. (2026) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-026-09058-5
Metadata
- Authors
- Mikhail, M. S., Anyaegbunam, A., Garfinkel, D., Palan, P. R., Basu, J., & Romney, S. L.
- Affiliations
- Albert Einstein College of Medicine (US)
- Corresponding author
- Mikhail, Magdy S.
- ORCID
- Basu, Jayasri
- Venue
- American Journal of Obstetrics and Gynecology
- Publisher
- Elsevier BV
- Published
- 1994-07
- Volume
- 171
- Issue
- 1
- Pages
- 150-157
- ISSN
- 0002-9378 (ISSN-L)
- OpenAlex
- W2063095299
- Cited by
- 229
- References
- 29
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 3 · 2023: 5 · 2022: 4 · 2021: 4 · 2020: 5 · 2019: 3 · 2018: 5 · 2017: 1 · 2016: 5 · 2015: 5 · 2014: 8 · 2013: 5 · 2012: 5
- FWCI
- 6.26
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Obstetrics and Gynecology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Health Sciences › Medicine › Biochemistry (medical) › Antioxidant Activity and Oxidative Stress
- Health Sciences › Medicine › Clinical Neurology › Neurological Complications and Syndromes
- Keywords
- preeclampsia, antioxidant nutrients, reduced ascorbic acid, vitamin C, alpha-tocopherol, vitamin E, beta-carotene, free radicals, oxidative stress, pregnancy complications
- MeSH terms
- Adolescent, Adult, Ascorbic Acid, Carotenoids, Female, Humans, Pilot Projects, Pre-Eclampsia, Pregnancy, Vitamin E, Case-Control Studies, beta Carotene
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
