Nitric oxide as an antioxidant

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

Palmer, R. M. J., Ferrige, A. G., & Moncada, S. (1987) · Nature · doi:10.1038/327524a0 · Cited by 10,704

A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples

Markwell, M. A. K., Haas, S. M., BIEBER, L. L., & Tolbert, N. E. (1978) · Analytical Biochemistry · doi:10.1016/0003-2697(78)90586-9 · Cited by 6,460

Oxygen-Derived Free Radicals in Postischemic Tissue Injury

Epstein, F. H., & McCord, J. M. (1985) · New England Journal of Medicine · doi:10.1056/nejm198501173120305 · Cited by 5,399

Nitric oxide: A cytotoxic activated macrophage effector molecule

Hibbs, J. B., Taintor, R. R., Vavrin, Z., & Rachlin, E. M. (1988) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(88)80015-9 · Cited by 2,034

Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells

Stuehr, D. J., & Nathan, C. F. (1989) · The Journal of Experimental Medicine · doi:10.1084/jem.169.5.1543 · Cited by 1,744

Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate

Marletta, M. A., Yoon, P. S., Iyengar, R., Leaf, C. D., & Wishnok, J. S. (1988) · Biochemistry · doi:10.1021/bi00424a003 · Cited by 1,601

Biosynthesis And Metabolism Of Endothelium-Derived Nitric Oxide

Ignarro, L. J. (1990) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pa.30.040190.002535 · Cited by 1,300

Biosynthesis of nitric oxide from l-arginine

Moncada, S., Palmer, R. M. J., & Higgs, E. A. (1989) · Biochemical Pharmacology · doi:10.1016/0006-2952(89)90403-6 · Cited by 1,222

The importance of free radicals and catalytic metal ions in human diseases.

Halliwell, B., & Gutteridge, J. M. C. (1985) · Molecular Aspects of Medicine · doi:10.1016/0098-2997(85)90001-9 · Cited by 941

Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase

Feelisch, M., & Noack, E. (1987) · European Journal of Pharmacology · doi:10.1016/0014-2999(87)90493-6 · Cited by 887

Spectrophotometric determination of serum iron at the submicrogram level with a new reagent (ferrozine)

Carter, P. M. (1971) · Analytical Biochemistry · doi:10.1016/0003-2697(71)90405-2 · Cited by 787

Initiation of lipid peroxidation in biological systems

Kanner, J., German, J. B., Kinsella, J., & Hultin, H. O. (1987) · C R C Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398709527457 · Cited by 382

Initiation of membranal lipid peroxidation by activated metmyoglobin and methemoglobin

Kanner, J., & Harel, S. (1985) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(85)90282-6 · Cited by 359

Electromagnetic Properties of Hemoproteins

Yonetani, T., Yamamoto, H., Erman, J. E., Leigh, J. S., & Reed, G. H. (1972) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)45449-5 · Cited by 345

On the participation of higher oxidation states of iron and copper in fenton reactions

Sutton, H. C., & Winterbourn, C. C. (1989) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(89)90160-3 · Cited by 340

Quantitative and kinetic characterization of nitric oxide and EDRF released from cultured endothelial cells

Kelm, M., Feelisch, M., Spahr, R., Piper, H. M., Noack, E., & Schrader, J. (1988) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(88)90675-4 · Cited by 339

Restoration of the responsiveness of purified guanylate cyclase to nitrosoguanidine, nitric oxide, and related activators by heme and hemeproteins. Evidence for involvement of the paramagnetic nitrosyl-heme complex in enzyme activation.

Craven, P. A., & DeRubertis, F. R. (1978) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)34310-7 · Cited by 328

Spectroscopic studies and bonding model for nitric oxide complexes of iron porphyrins

Wayland, B. B., & Olson, L. W. (1974) · Journal of the American Chemical Society · doi:10.1021/ja00826a013 · Cited by 293

Cooperativity in the dissociation of nitric oxide from hemoglobin.

Moore, E. G., & Gibson, Q. H. (1976) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)33557-3 · Cited by 292

Generation of nitric oxide by human neutrophils

Wright, C. D., Mülsch, A., Busse, R., & Oßwald, H. (1989) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(89)92506-0 · Cited by 292

Conformation, co-operativity and ligand binding in human hemoglobin

Cassoly, R., & Gibson, Q. H. (1975) · Journal of Molecular Biology · doi:10.1016/0022-2836(75)90382-4 · Cited by 259

Helichrome: synthesis and enzymic activity of a designed hemeprotein

Sasaki, T., & Kaiser, E. T. (1989) · Journal of the American Chemical Society · doi:10.1021/ja00183a065 · Cited by 244

Nitric oxide from L-arginine stimulates the soluble guanylate cyclase in adrenal glands

Palacios‐Callender, M., Knowles, R. G., Palmer, R. M. J., & Moncada, S. (1989) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(89)80037-3 · Cited by 237

Paramagnetic Resonance Study of Nitric Oxide Hemoglobin

Kon, H. (1968) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)93262-x · Cited by 230

Oxidizing intermediates in the reaction of ferrous EDTA with hydrogen peroxide. Reactions with organic molecules and ferrocytochrome c.

Rush, J. D., & Koppenol, W. H. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)62677-3 · Cited by 200

An Electron Spin Resonance Study of Some Complexes of Iron, Nitric Oxide, and Anionic Ligands

McDonald, C. C., Phillips, W. D., & Mower, H. F. (1965) · Journal of the American Chemical Society · doi:10.1021/ja01093a007 · Cited by 193

Vascular smooth muscle-derived relaxing factor (MDRF) and its close similarity to nitric oxide

Wood, K. S., Buga, G. M., Byrns, R. E., & Ignarro, L. J. (1990) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(90)91243-l · Cited by 177

Trapping of nitric oxide produced during denitrification by extracellular hemoglobin.

Goretski, J., & Hollocher, T. C. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)69208-7 · Cited by 174

Quantitation of the hydroxyl radical by reaction with dimethyl sulfoxide

Steiner, M. G., & Babbs, C. F. (1990) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(90)90288-a · Cited by 162

Enzymatic formation of nitrogen oxides from L-arginine in bovine brain cytosol

Schmidt, H. H. H. W., Wilke, P., Evers, B., & Böhme, E. (1989) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(89)91067-x · Cited by 157

Free radical‐induced pathology

Clark, I. A., Cowden, W. B., & Hunt, N. H. (1985) · Medicinal Research Reviews · doi:10.1002/med.2610050303 · Cited by 148

Developments in inorganic nitrogen chemistry

Colburn, C. B. (1966) · Medical Entomology and Zoology · Cited by 147

Picosecond and nanosecond geminate recombination of myoglobin with carbon monoxide, oxygen, nitric oxide and isocyanides

Jongeward, K. A., Magde, D., Taube, D. J., Marsters, J. C., Traylor, T. G., & Sharma, V. S. (1988) · Journal of the American Chemical Society · doi:10.1021/ja00210a011 · Cited by 133

The effect of pH on the conversion of superoxide to hydroxyl free radicals

Baker, M. S., & Gebicki, J. M. (1984) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(84)90348-5 · Cited by 127

The Generation of Ferryl or Hydroxyl Radicals During Interaction of Haemproteins with Hydrogen Peroxide

Harel, S., & Kanner, J. (1988) · Free Radical Research Communications · doi:10.3109/10715768809068555 · Cited by 110

Mechanisms of reoxygenation injury in myocardial infarction: Implications of a myoglobin redox cycle

Galaris, D., Eddy, L. J., Arduini, A., Cadenas, E., & Hochstein, P. (1989) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(89)80125-1 · Cited by 95

Formation of Bovine Nitrosylmyoglobin. I. pH 4.5-6.5*

Fox, J. B., & Thomson, J. S. (1963) · Biochemistry · doi:10.1021/bi00903a012 · Cited by 85

The interaction of oxymyoglobin with hydrogen peroxide: The formation of ferrylmyoglobin at moderate excesses of hydrogen peroxide

Whitburn, K. D. (1987) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(87)90195-0 · Cited by 80

The role of NADPH-cytochrome b5 reductase in microsomal lipid peroxidation

Bidlack, W. R., Okita, R. T., & Hochstein, P. E. (1973) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(73)90684-0 · Cited by 79

Iron Release from Metmyoglobin, Methaemoglobin and Cytochrome C by A System Generating Hydrogen Peroxide

Harel, S., Salan, M. A., & Kanner, J. (1988) · Free Radical Research Communications · doi:10.3109/10715768809068554 · Cited by 78

Co-oxidation of salicylate and cholesterol during the oxidation of metmyoglobin by H2O2

Galaris, D., Mira, D., Sevanian, A., Cadenas, E., & Hochstein, P. (1988) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(88)90184-1 · Cited by 63

Antioxidative effect of nitrite in cured meat products: nitric oxide-iron complexes of low molecular weight

Kanner, J., Harel, S., Shagalovich, J., & Berman, S. (1984) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf00123a023 · Cited by 61

Nitric‐oxide myoglobin as an inhibitor of lipid oxidation

Kanner, J., BEN‐GERA, I., & Berman, S. (1980) · Lipids · doi:10.1007/bf02534419 · Cited by 48

Haemoglobin and Myoglobin as Inhibitors of Hydroxyl Radical Generation in a Model System of “Iron Redox” Cycle

Harel, S., & Kanner, J. (1989) · Free Radical Research Communications · doi:10.3109/10715768909073422 · Cited by 30

Significance of peroxynitric acid in atmospheric chemistry of nitrogen oxides

Cox, R. A., Derwent, R. G., & HUTTON, A. J. L. (1977) · Nature · doi:10.1038/270328a0 · Cited by 29

Rates of OH radical reactions. II. The combination reaction OH+NO+M

Overend, R. P., Paraskevopoulos, G., & Black, C. (1976) · The Journal of Chemical Physics · doi:10.1063/1.431984 · Cited by 23

Gas-phase reactions of the hydroperoxide and peroxyformate anions

Bowie, J. H., DePuy, C. H., Sullivan, S. A., & Bierbaum, V. M. (1986) · Canadian Journal of Chemistry · doi:10.1139/v86-175 · Cited by 16

The ferritins: molecular properties, iron storage function and cellular regulation

Harrison, P. M., & Arosio, P. (1996) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/0005-2728(96)00022-9 · Cited by 2,667

Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-κB activation

Surh, Y., Chun, K., Cha, H.-H., Han, S. S., Keum, Y., Park, K.-K., & Lee, S. S. (2001) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/s0027-5107(01)00183-x · Cited by 1,620

Chemical biology of nitric oxide: insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide

Wink, D. A., & Mitchell, J. B. (1998) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(98)00092-6 · Cited by 1,606

Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives

Rubbo, H., Radí, R., Trujillo, M., Telleri, R., Kalyanaraman, B., Barnes, S., KIRK, M. C., & Freeman, B. Α. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)47160-8 · Cited by 1,350

Perspectives series: host/pathogen interactions. Mechanisms of nitric oxide-related antimicrobial activity.

Fang, F. C. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119473 · Cited by 1,139

Kinetic and mechanistic studies of the reactions of nitrogen monoxide and nitrite with ferryl myoglobin

Herold, S., & Rehmann, F. K. (2001) · JBIC Journal of Biological Inorganic Chemistry · doi:10.1007/s007750100231 · Cited by 78

Nitric‐oxide myoglobin as an inhibitor of lipid oxidation

Kanner, J., BEN‐GERA, I., & Berman, S. (1980) · Lipids · doi:10.1007/bf02534419 · Cited by 48

The modulation of ferryl myoglobin formation and its oxidative effects on low density lipoproteins by nitric oxide

Dee, G., Rice-Evans, C. A., Obeyesekera, S., Meraji, S., Jacobs, M., & Bruckdorfer, K. R. (1991) · FEBS Letters · doi:10.1016/0014-5793(91)81338-9 · Cited by 93

Reduction of Ferrylmyoglobin and Ferrylhemoglobin by Nitric Oxide: A Protective Mechanism against Ferryl Hemoprotein-Induced Oxidations

Gorbunov, N. V., Osipov, A. N., Day, B. W., Zayas-Rivera, B., Kagan, V. E., & Elsayed, N. M. (1995) · Biochemistry · doi:10.1021/bi00020a014 · Cited by 123

Does the Oxidation of Nitric Oxide by oxyMyoglobin Share an Intermediate with the metMyoglobin-Catalyzed Isomerization of Peroxynitrite?

Koebke, K. J., Pauly, D. J., Lerner, L., Liu, X., & Pacheco, A. A. (2013) · Inorganic Chemistry · doi:10.1021/ic400697a · Cited by 26