The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Structures and fatty acid compositions of neutral glycosphingolipids of human plasma
Abstract
Major neutral glycosphingolipids were isolated from human plasma and their structures and fatty acid compositions studied. The four neutral glycosphingolipids of plasma were characterized as Glc beta(1 leads to 1)ceramide, Gal beta(1 leads to 1)- ceramide, Gal beta(1 leads to 4) Glc beta (1 leads to 1)ceramide, Gal alpha(1 leads to 4) Gal beta(1 leads to 4) Glc beta(1 leads to 1)ceramide and GalNAc beta(1 leads to 3) Gal (1 leads to 4) Gal (1 leads to 4) Glc beta(1 leads to 1)-ceramide. The glycosphingolipids contained mostly short chain fatty acids of which most prominent was C16. Erythrocyte glucosylceramide and lactosylceramide exhibited similar fatty acid compositions as their plasma counterparts. Triglycosylceramide and globoside of erythrocytes contained almost exclusively long-chain fatty acids. In lactosylceramide obtained from "p" erythrocytes, an accumulation of long-chain fatty acids was found; this accumulation was not observed, however, in lactosylceramide isolated from "p" plasma. It was concluded that plasma and erythrocyte glycosphingolipids are synthesized at separate sites where short- and long-chain fatty acids, respectively, are available. Plasma and erythrocyte glucosylceramide, and probably a fraction of lactosylceramide, exchange between plasma and erythrocyte pools. The latter conclusion is discussed in the light of the relative roles of carbohydrate and lipid moieties of the glycosphingolipids in maintaining their association with erythrocyte membrane…
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“The CMH of human plasma was comprised of both glucosyl-(GlcCer) and galactosylceramides (GalCer), as has been reported before (27)(28)(29), with higher proportions of GlcCer.”
From Lipidomics reveals a remarkable diversity of lipids in human plasma (2010) · cites this paper as [29]
Citations
Cites
Determination of aminosugar linkages in glycolipids by methylation
Stellner, K., Saito, H., & Hakomori, S.-I. (1973) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(73)90138-0 · Cited by 830
Quantitative determination of the neutral glycosyl ceramides in human blood
Vance, D. E., & Sweeley, C. C. (1967) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)38884-2 · Cited by 586
A Sphingolipid Having a Novel Type of Ceramide and Lacto-N-Fucopentaose III
Yang, H.-J., & Hakomori, S.-I. (1971) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)76958-0 · Cited by 484
Gangliosides of human, bovine, and rabbit plasma
Yu, R. K., & Ledeen, R. W. (1972) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39374-3 · Cited by 353
Lipid composition of human serum lipoproteins
Skipski, V. P., Barclay, M., Barclay, R. K., Fetzer, V., Good, J., & Archibald, F. M. (1967) · Biochemical Journal · doi:10.1042/bj1040340 · Cited by 303
Glycosphingolipids with Lewis Blood Group Activity: Uptake by Human Erythrocytes
Marcus, D. M., & Cass, L. E. (1969) · Science · doi:10.1126/science.164.3879.553 · Cited by 261
Kościelak, J., Miller‐Podraza, H., Krauze, R. Y., & Piasek, A. (1976) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1976.tb11083.x · Cited by 180
Self-citationKościelak, J., Piasek, A., Górniak, H., Gardas, A., & Gregor, A. (1973) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1973.tb02978.x · Cited by 144
Self-citationThe separation of neutral blood-serum glycolipids by thin-layer chromatography
Svennerholm, E., & Svennerholm, L. T. (1963) · Biochimica et Biophysica Acta · doi:10.1016/0006-3002(63)90773-x · Cited by 131
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Research works printed but not linked: 2
- Ando, 1976, Biochim. Biophys. Acta, 424, 18
- Marcus, 1976, 73, 3263
Cited by
Lipidomics reveals a remarkable diversity of lipids in human plasma
Quehenberger, O., Armando, A. M., Brown, A. H., Milne, S. B., Myers, D. S., Merrill, A. H., Bandyopadhyay, S., Jones, K. N., Kelly, S., Shaner, R. L., et al. (2010) · Journal of Lipid Research · doi:10.1194/jlr.m009449 · Cited by 1,341
Metadata
- Authors
- Kościelak, J., Maśliński, W., Zieleński, J., Zdebska, E., Brudzyński, T., Miller-Podraza, H., & Cedergren, B.
- Venue
- Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism
- Publisher
- Elsevier BV
- Published
- 1978-09
- Volume
- 530
- Issue
- 3
- Pages
- 385-393
- ISSN
- 0005-2760
- Cited by
- 14
- References
- 22
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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