Interactions of hepatic cytochromes P-450 with steroid hormones

Cytochrome P-450: Structure, Mechanism, and Biochemistry

de Montellano, O., & Paul, R. (1986) · Medical Entomology and Zoology · Cited by 2,667 · see citing works

Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes Memorial Lecture.

Conney, A. H. (1982) · PubMed · Cited by 1,557 · see citing works

Benzo[alpha]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes.

Gelboin, H. V. (1980) · Physiological Reviews · doi:10.1152/physrev.1980.60.4.1107 · Cited by 1,280 · see citing works

Purification and characterization of liver microsomal cytochromes P-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or .beta.-naphthoflavone

Guengerich, F. P., Dannan, G. A., Wright, S. T., Martin, M. V., & Kaminsky, L. S. (1982) · Biochemistry · doi:10.1021/bi00266a045 · Cited by 1,012 · see citing works

The P450 Gene Superfamily: Recommended Nomenclature

Nebert, D. W., Adesnik, M., Coon, M. J., Estabrook, R. W., Gonzalez, F. J., Guengerich, F. P., GUNSALUS, I. C., Johnson, E. F., KEMPER, B. W., Levin, W., et al. (1987) · DNA · doi:10.1089/dna.1987.6.1 · Cited by 818 · see citing works

Sexual Dimorphism in the Control of Growth Hormone Secretion*

Jansson, J., Edén, S., & Isaksson, O. G. P. (1985) · Endocrine Reviews · doi:10.1210/edrv-6-2-128 · Cited by 745 · see citing works

Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism.

Guengerich, F. P., Martin, M. V., Beaune, P. H., Kremers, P. G., Wolff, T., & Waxman, D. J. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)89213-x · Cited by 724 · see citing works

Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes

Waxman, D. J., Dannan, G. A., & Guengerich, F. P. (1985) · Biochemistry · doi:10.1021/bi00337a023 · Cited by 598 · see citing works

Metabolism of polycyclic aromatic hydrocarbons: etiologic role in carcinogenesis.

Pelkonen, O., & Nebert, D. W. (1982) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)00051-1 · Cited by 514 · see citing works

Mode of Action of Pituitary Growth Hormone on Target Cells

Isaksson, O. G. P., Edén, S., & Jansson, J. (1985) · Annual Review of Physiology · doi:10.1146/annurev.ph.47.030185.002411 · Cited by 450 · see citing works

Regio- and stereoselective metabolism of two C19 steroids by five highly purified and reconstituted rat hepatic cytochrome P-450 isozymes.

Wood, A. W., Ryan, D. E., Thomas, P. E., & Levin, W. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)32132-x · Cited by 338 · see citing works

Regulation of testosterone hydroxylation by rat liver microsomal cytochrome P-450

Sonderfan, A. J., Arlotto, M. P., Dutton, D. R., McMillen, S. K., & Parkinson, A. (1987) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(87)90291-8 · Cited by 325 · see citing works

Isolation, complementary DNA sequence, and regulation of rat hepatic lauric acid omega-hydroxylase (cytochrome P-450LA omega). Identification of a new cytochrome P-450 gene family.

Hardwick, J. P., Song, B. J., Huberman, E., & Gonzalez, F. J. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)75857-8 · Cited by 312 · see citing works

Sex Steroid Induced Changes in Hepatic Enzymes

Gustafsson, J.-Α., Mode, A., Norstedt, G., & Skett, P. (1983) · Annual Review of Physiology · doi:10.1146/annurev.ph.45.030183.000411 · Cited by 312 · see citing works

Identification of the cytochrome P-450 induced by macrolide antibiotics in rat liver as the glucocorticoid responsive cytochrome P-450p

Wrighton, S. A., Maurel, P., Schuetz, E. G., Watkins, P. B., Young, B., & Guzelian, P. S. (1985) · Biochemistry · doi:10.1021/bi00330a010 · Cited by 299 · see citing works

Characterization of three highly purified cytochromes P-450 from hepatic microsomes of adult male rats.

Ryan, D. E., Iida, S., Wood, A. W., Thomas, P. E., Lieber, C. S., & Levin, W. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)43594-0 · Cited by 297 · see citing works

Pregnenolone 16 Alpha-Carbonitrile-Inducible P-450 Gene Family: Gene Conversion and Differential Regulation

Gonzalez, F. J., Song, B. J., & Hardwick, J. P. (1986) · Molecular and Cellular Biology · doi:10.1128/mcb.6.8.2969 · Cited by 296 · see citing works

Rat hepatic cytochrome P-450 isoenzyme 2c. Identification as a male-specific, developmentally induced steroid 16 alpha-hydroxylase and comparison to a female-specific cytochrome P-450 isoenzyme.

Waxman, D. J. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)42574-9 · Cited by 270 · see citing works

Hormonal and developmental regulation of expression of the hepatic microsomal steroid 16 alpha-hydroxylase cytochrome P-450 apoprotein in the rat.

Morgan, E. T., MacGeoch, C., & Gustafsson, J.-Α. (1985) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)38963-9 · Cited by 264 · see citing works

Separation, purification, and characterization of a novel form of hepatic cytochrome P-450 from rats treated with pregnenolone-16 alpha-carbonitrile.

Elshourbagy, N. A., & Guzelian, P. S. (1980) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)86026-x · Cited by 255 · see citing works

Sex difference of cytochrome P-450 in the rat: Purification, characterization, and quantitation of constitutive forms of cytochrome P-450 from liver microsomes of male and female rats

Kamataki, T., Maeda, K., Yamazoe, Y., et al. (1983) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(83)90087-5 · Cited by 234 · see citing works

Secretory rhythm of growth hormone regulates sexual differentiation of mouse liver

Norstedt, G., & Palmiter, R. D. (1984) · Cell · doi:10.1016/0092-8674(84)90030-8 · Cited by 231 · see citing works

Genes for Cytochrome P-450 and Their Regulatio

Adesnik, M., Atchison, M. L., & Nebert, D. W. (1986) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409238609084657 · Cited by 225 · see citing works

Phenobarbital-induced rat liver cytochrome P-450. Purification and characterization of two closely related isozymic forms.

Waxman, D. J., & Walsh, C. T. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)34039-0 · Cited by 221 · see citing works

Purification and characterization of a minor form of hepatic microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls

Ryan, D. E., Thomas, P. E., & Levin, W. (1982) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(82)90212-0 · Cited by 217 · see citing works

Estradiol 16 alpha-hydroxylation in the mouse correlates with mammary tumor incidence and presence of murine mammary tumor virus: a possible model for the hormonal etiology of breast cancer in humans.

Bradlow, H. L., Hershcopf, R. J., Martucci, C. P., & Fishman, J. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.18.6295 · Cited by 204 · see citing works

Suppression of levels of phenobarbital-inducible rat liver cytochrome P-450 by pituitary hormone.

Yamazoe, Y., Shimada, M., Murayama, N., et al. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)48254-3 · Cited by 176 · see citing works

Induction of cytochrome P-450 by glucocorticoids in rat liver. I. Evidence that glucocorticoids and pregnenolone 16 alpha-carbonitrile regulate de novo synthesis of a common form of cytochrome P-450 in cultures of adult rat hepatocytes and in the liver in vivo.

Schuetz, E. G., Wrighton, S. A., Barwick, J. L., et al. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)43507-1 · Cited by 175 · see citing works

Imprinting of Growth Hormone Secretion, Body Growth, and Hepatic Steroid Metabolism by Neonatal Testosterone*

Jansson, J., Ekberg, S., Isaksson, O. G. P., Mode, A., & Gustafsson, J.-Α. (1985) · Endocrinology · doi:10.1210/endo-117-5-1881 · Cited by 172 · see citing works

Hormonal regulation of rat liver microsomal enzymes. Role of gonadal steroids in programming, maintenance, and suppression of delta 4-steroid 5 alpha-reductase, flavin-containing monooxygenase, and sex-specific cytochromes P-450.

Dannan, G. A., Guengerich, F. P., & Waxman, D. J. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)67446-0 · Cited by 167 · see citing works

Continuous Infusion of Growth Hormone Feminizes Hepatic Steroid Metabolism in the Rat*

Mode, A., Norstedt, G., Šimić, B., Eneroth, P. H. E., & Gustafsson, J.-Α. (1981) · Endocrinology · doi:10.1210/endo-108-6-2103 · Cited by 158 · see citing works

Purification and characterization of the rat liver microsomal cytochrome P-450 involved in the 4-hydroxylation of debrisoquine, a prototype for genetic variation in oxidative drug metabolism

Larrey, D. G., Distlerath, L. M., Dannan, G. A., et al. (1984) · Biochemistry · doi:10.1021/bi00307a039 · Cited by 150 · see citing works

Complete cDNA sequence of a cytochrome P-450 inducible by glucocorticoids in human liver.

Molowa, D. T., Schuetz, E. G., Wrighton, S. A., et al. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.14.5311 · Cited by 143 · see citing works

Irreversible Androgenic Programming at Birth of Microsomal and Soluble Rat Liver Enzymes Active on 4-Androstene-3,17-dione and 5α-Androstane-3α,17β-diol

Gustafsson, J.-Α., & Stenbeŕg, Å. (1974) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)42988-8 · Cited by 142 · see citing works

Debrisoquine 4-Hydroxylase: Characterization of a New P450 Gene Subfamily, Regulation, Chromosomal Mapping, and Molecular Analysis of the DA Rat Polymorphism

Gonzalez, F. J., Matsunaga, T., Nagata, K., Meyer, U., Nebert, D. W., Pastewka, J. V., Kozak, C. A., Gillette, J. R., Gelboin, H. V., & Hardwick, J. P. (1987) · DNA · doi:10.1089/dna.1987.6.149 · Cited by 136 · see citing works

Regulation of cytochrome P-450. Immunochemical quantitation of eight isozymes in liver microsomes of rats treated with polybrominated biphenyl congeners.

Dannan, G. A., Guengerich, F. P., Kaminsky, L. S., et al. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)33190-9 · Cited by 132 · see citing works

17β-Estradiol 2- and 4-Hydroxylation Catalyzed by Rat Hepatic Cytochrome P-450: Roles of Individual Forms, Inductive Effects, Developmental Patterns, and Alterations by Gonadectomy and Hormone Replacement*

Dannan, G. A., Porubek, D. J., Nelson, S. D., et al. (1986) · Endocrinology · doi:10.1210/endo-118-5-1952 · Cited by 131 · see citing works

Studies on the rate-limiting enzyme component in the microsomal monooxygenase system. Incorporation of purified NADPH-cytochrome c reductase and cytochrome P-450 into rat liver microsomes.

Miwa, G. T., West, S. B., & Lu, A. (1978) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)62336-7 · Cited by 118 · see citing works

Identification of a human liver cytochrome P-450 homologous to the major isosafrole-inducible cytochrome P-450 in the rat.

Wrighton, S. A., Campanile, C., Thomas, P. E., et al. (1986) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)10261-7 · Cited by 113 · see citing works

Age- and sex-related expression of cytochromes P450f and P450g in rat liver

Bandiera, S. M., Ryan, D. E., Levin, W., & Thomas, P. E. (1986) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(86)90521-7 · Cited by 109 · see citing works

Structural analysis and specific expression of microsomal cytochrome P-450(M-1) mRNA in male rat livers.

Yoshioka, H., Morohashi, K.-I., Sogawa, K., et al. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)75695-6 · Cited by 108 · see citing works

Purification, characterization, and pituitary regulation of the sex-specific cytochrome P-450 15 beta-hydroxylase from liver microsomes of untreated female rats.

MacGeoch, C., Morgan, E. T., Halpert, J. R., et al. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)42567-1 · Cited by 106 · see citing works

Rat testosterone 7 alpha-hydroxylase. Isolation, sequence, and expression of cDNA and its developmental regulation and induction by 3-methylcholanthrene.

Nagata, K., Matsunaga, T., Gillette, J. R., et al. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)61575-3 · Cited by 103 · see citing works

Effect of Growth Hormone and Ectopic Transplantation of Pituitary Gland on Sex-Specific Forms of Cytochrome P-450 and Testosterone and Drug Oxidations in Rat Liver1

Kato, R., Yamazoe, Y., Shimada, M., et al. (1986) · The Journal of Biochemistry · doi:10.1093/oxfordjournals.jbchem.a121802 · Cited by 101 · see citing works

Sequence of two related P-450 mRNAs transcriptionally increased during rat development. An R.dre.1 sequence occupies the complete 3' untranslated region of a liver mRNA.

Gonzalez, F. J., Kimura, S., Song, B. J., et al. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)67437-x · Cited by 91 · see citing works

Multiple forms of cytochrome P-450 related to forms induced marginally by phenobarbital. Differences in structure and in the metabolism of alkoxyresorufins

Wolf, C. R., Seilman, S., Oesch, F., et al. (1986) · Biochemical Journal · doi:10.1042/bj2400027 · Cited by 90 · see citing works

Cytochrome P-450 isoenzyme content and monooxygenase activities in rat liver: effect of ontogenesis and pretreatment by phenobarbital and 3-methylcholanthrene.

Cresteil, T., Beaune, P. H., Célier, C., et al. (1986) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)38816-6 · Cited by 88 · see citing works

Purification and characterization of a new form (RLM2) of liver microsomal cytochrome P-450 from untreated rat.

Jansson, I., Mole, J. E., & Schenkman, J. B. (1985) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)88891-3 · Cited by 86 · see citing works

Cytochrome P-450s: polymorphic multigene families involved in carcinogen activation

Wolf, C. R. (1986) · Trends in Genetics · doi:10.1016/0168-9525(86)90232-5 · Cited by 85 · see citing works

Cytochrome P‐450 isozyme/isozyme functional interactions and NADPH‐cytochrome P‐450 reductase concentrations as factors in microsomal metabolism of warfarin

Kaminsky, L. S., & Guengerich, F. P. (1985) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1985.tb08950.x · Cited by 85 · see citing works

Purification and characterization of cholesterol 7 alpha-hydroxylase from rat liver microsomes.

Ogishima, T., Deguchi, S., & Okuda, K. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)47615-6 · Cited by 79 · see citing works

Monoclonal antibodies distinguish among isozymes of the cytochrome P-450b subfamily

Reik, L. M., Levin, W., Ryan, D. E., et al. (1985) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(85)90221-8 · Cited by 70 · see citing works

An unusual metabolite of testosterone. 17 beta-Hydroxy-4,6-androstadiene-3-one.

Nagata, K., Liberato, D. J., Gillette, J. R., & Sasame, H. A. (1986) · Drug Metabolism and Disposition · doi:10.1016/s0090-9556(25)08874-9 · Cited by 70 · see citing works

Metabolism of progesterone and estradiol by microsomes and purified cytochrome P-450 RLM3 and RLM5.

Cheng, K. C., & Schenkman, J. B. (1984) · Drug Metabolism and Disposition · doi:10.1016/s0090-9556(25)07709-8 · Cited by 68 · see citing works

Human-liver cytochromes P-450 involved in polymorphisms of drug oxidation

Guengerich, F. P., Distlerath, L. M., Reilly, P. E. B., et al. (1986) · Xenobiotica · doi:10.3109/00498258609050245 · Cited by 68 · see citing works

Postnatal development of constitutive forms of cytochrome p-450 in liver microsomes of male and female rats

Maeda, K., Kamataki, T., Nagai, T., et al. (1984) · Biochemical Pharmacology · doi:10.1016/0006-2952(84)90252-1 · Cited by 60 · see citing works

Developmental and hormonal regulation of alpha 2u-globulin gene transcription.

Kulkarni, A. B., Gubits, R. M., & Feigelson, P. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.9.2579 · Cited by 58 · see citing works

Monoclonal antibodies inhibitory to rat hepatic cytochromes P-450: P-450 form specificities and use as probes for cytochrome P-450-dependent steroid hydroxylations.

Waxman, D. J., Lapenson, D. P., Park, S. S., et al. (1987) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)13046-0 · Cited by 56 · see citing works

The interaction of cytochrome b5 with four cytochrome P-450 enzymes from the untreated rat.

Jansson, I., Tamburini, P. P., Favreau, L. V., et al. (1985) · Drug Metabolism and Disposition · doi:10.1016/s0090-9556(25)08233-9 · Cited by 56 · see citing works

Evidence for functional and structural multiplicity of pregnenolone-16.alpha.-carbonitrile-inducible cytochrome P-450 isozymes in rat liver microsomes

Graves, P. E., Kaminsky, L. S., & Halpert, J. R. (1987) · Biochemistry · doi:10.1021/bi00387a022 · Cited by 54 · see citing works

Rat hepatic cytochrome P-450 isozyme specificity for the metabolism of the steroid sulfate, 5α-androstane-3α,17β-diol-3,17-disulfate

Ryan, D. E., Dixon, R., Evans, R. H., et al. (1984) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(84)90489-2 · Cited by 52 · see citing works

Phenotypic differences in expression of cytochrome P-450g but not its mRNA in outbred male Sprague-Dawley rats

McClellan‐Green, P. D., Waxman, D. J., Caveness, M. B., et al. (1987) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(87)90632-1 · Cited by 48 · see citing works

Hydroxylations of Bile Acids by Reconstituted Systems from Rat Liver Microsomes

Björkhem, I., Danielsson, H., & Wikvall, K. (1974) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)42176-5 · Cited by 47 · see citing works

6βHydroxy cortisol: A Noninvasive Indicator of Enzyme Induction*

Saenger, P. H., Förster, E., & Kream, J. (1981) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-52-3-381 · Cited by 45 · see citing works

Preparation and characterization of monoclonal antibodies to pregnenolone 16-α-carbonitrile inducible rat liver cytochrome P-450

Park, S., Waxman, D. J., Miller, H., et al. (1986) · Biochemical Pharmacology · doi:10.1016/0006-2952(86)90477-6 · Cited by 44 · see citing works

Isolation and characterization of cDNA clones for cytochromes P-450 immunochemically related to rat hepatic P-450 form PB-1

Friedberg, T., Waxman, D. J., Atchison, M. L., et al. (1986) · Biochemistry · doi:10.1021/bi00372a028 · Cited by 37 · see citing works

Rat hepatic cholesterol 7α-hydroxylase: Biochemical properties and comparison to constitutive and xenobiotic-inducible cytochrome P-450 enzymes

Waxman, D. J. (1986) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(86)90592-8 · Cited by 32 · see citing works

Hydroxylation, sulfation, and conjugation of bile acids in rat hepatoma and hepatocyte cultures under the influence of glucocorticoids.

Lambiotte, M., & Thierry, N. (1980) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)70295-6 · Cited by 28 · see citing works

Multiple sites of steroid hydroxylation by the liver microsomal cytochrome P-450 system: primary and secondary metabolism of androstenedione

Sheets, J. J., & Estabrook, R. W. (1985) · Biochemistry · doi:10.1021/bi00344a043 · Cited by 25 · see citing works

19 P-450 Oxygenases in Lipid Transformation

Coon, M. J., & Koop, D. R. (1983) · The Enzymes · doi:10.1016/s1874-6047(08)60317-0 · Cited by 18 · see citing works

Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: a comprehensive review

Schiffer, L., Barnard, L., Baranowski, E. S., Gilligan, L. C., Taylor, A. E., Arlt, W., Shackleton, C. H. L., & Storbeck, K.-H. (2019) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2019.105439 · Cited by 450 · see citing works

Steroid hormone biotransformation and xenobiotic induction of hepatic steroid metabolizing enzymes

You, L. (2004) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2004.01.006 · Cited by 145 · see citing works

Farnesoid X receptor alpha: a molecular link between bile acids and steroid signaling

Baptissart, M., Vega, A., Martinot, E., Baron, S., Lobaccaro, J.-M. A., & Volle, D. H. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1387-0 · Cited by 32 · see citing works

A systematic comparison of the MetaCyc and KEGG pathway databases

Altman, T., Travers, M., Kothari, A., Caspi, R., & Karp, P. D. (2013) · BMC Bioinformatics · doi:10.1186/1471-2105-14-112 · Cited by 174 · see citing works

Gene Annotation and Pathway Mapping in KEGG

Aoki-Kinoshita, K. F., & Kanehisa, M. I. (2007) · Methods in molecular biology · doi:10.1007/978-1-59745-515-2_6 · Cited by 310 · see citing works

Recent Progress and Application of KEGG Database in the Research of Bioinformatics

Hui-sheng, F. (2012) · Pharmaceutical biotechnology · Cited by 4 · see citing works

KEGG for linking genomes to life and the environment

Kanehisa, M. I., Araki, M., Goto, S., Hattori, M., Hirakawa, M., Itoh, M., Katayama, T., Kawashima, S., Okuda, S., Tokimatsu, T., et al. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkm882 · Cited by 6,828 · see citing works

KEGG: new perspectives on genomes, pathways, diseases and drugs

Kanehisa, M., Furumichi, M., Tanabe, M., Sato, Y., & Morishima, K. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkw1092 · Cited by 8,865 · see citing works