Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 598

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Inhibition of mammalian 5-lipoxygenase and cyclo-oxygenase by flavonoids and phenolic dietary additives

Laughton, Miranda J., Evans, Patricia J., Moroney, Michele A., Hoult, J.R.S., Halliwell, Barry·1991·Biochemical Pharmacology
DOI 10.1016/0006-2952(91)90501-u
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/0006-2952(91)90501-u

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 1 references

Research works printed but not linked: 29

  1. Lewis, 1990, Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human disease, N Engl J Med, 323, 645, 10.1056/NEJM199009063231006 · DOI
  2. Cashman, 1985, Leukotriene biosynthesis inhibitors, Pharm Res, 323, 253, 10.1023/A:1016381215385 · doi:10.1023/a:1016381215385
  3. Moroney, 1988, Selectivity of neutrophil 5-lipoxygenase and cyclo-oxygenase inhibition by an anti-inflammatory flavonoid glycoside and related aglycone flavonoids, J Pharm Pharmacol, 40, 782, 10.1111/j.2042-7158.1988.tb05173.x · DOI · Paper page
  4. Takahama, 1985, Inhibition of lipoxygenase-dependent lipid peroxidation by quercetin: mechanism of anti-oxidative function, Phytochemistry, 24, 1443, 10.1016/S0031-9422(00)81040-7 · DOI
  5. Yoshimoto, 1983, Flavonoids: potent inhibitors of arachidonate 5-lipoxygenase, Biochem Biophys Res Commun, 116, 612, 10.1016/0006-291X(83)90568-5 · DOI · Paper page
  6. Baumann, 1980, Flavonoids and related compounds as inhibitors of arachidonic acid peroxidation, Prostaglandins, 20, 627, 10.1016/0090-6980(80)90103-3 · DOI · Paper page
  7. Riendeau, 1989, Stimulation of 5-lipoxygenase activity under conditions which promote lipid peroxidation, Biochem J, 263, 565, 10.1042/bj2630565 · doi:10.1042/bj2630565
  8. Slater, 1987, Free radical scavenging properties of modulators of eicosanoid metabolism, Adv Prostaglandin Thromboxane Res, 17, 1098
  9. Bindoli, 1977, Inhibitory action of silymarin on lipid peroxide formation in rat liver mitochondria and microsomes, Biochem Pharmacol, 26, 2405, 10.1016/0006-2952(77)90449-X · DOI
  10. Ratty, 1988, Effects of flavonoids on non-enzymatic lipid peroxidation: structure-activity relationship, Biochem Med, 39, 69
  11. Laughton, 1989, Antioxidant and pro-oxidant actions of the plant phenolics quercetin, gossypol and myricetin, Biochem Pharmacol, 38, 2859, 10.1016/0006-2952(89)90442-5 · DOI · Paper page
  12. Reddanna, 1985, Inhibition of 5-lipoxygenase by vitamin E, FEBS Lett, 193, 39, 10.1016/0014-5793(85)80075-2 · doi:10.1016/0014-5793(85)80075-2
  13. Halliwell, 1990, How to characterise a biological antioxidant, Free Radical Res Commun, 9, 1, 10.3109/10715769009148569 · DOI · Paper page
  14. Chamulitrat, 1989, Lipid peroxyl radical intermediates in the peroxidation of polyunsaturated fatty acids by lipoxygenase, J Biol Chem, 264, 20968, 10.1016/S0021-9258(19)30031-6 · DOI
  15. Thody, 1987, Studie s on theanti-oxidant activity of 5-lipoxygenase inhibitors, Biochem Soc Trans, 15, 416, 10.1042/bst0150416 · doi:10.1042/bst0150416
  16. Torel, 1986, Antioxidant activity of flavonoids and reactivity with peroxy radical, Phytochemistry, 25, 383, 10.1016/S0031-9422(00)85485-0 · DOI · Paper page
  17. Kemal, 1987, Reductive inactivation of soybean lipoxygenase I by catechols: a possible mechanism for regulation of lipoxygenase activity, Biochemistry, 26, 7064, 10.1021/bi00396a031 · DOI · Paper page
  18. Van der Zee, 1989, Formation of free radical metabolites in the reaction between soybean lipoxygenase and its inhibitors. An ESR study, Biochemistry, 28, 8363, 10.1021/bi00447a015 · doi:10.1021/bi00447a015
  19. Boyer, 1988, Reduction and release of ferritin iron by plant phenolics, J Inorg Biochem, 32, 171, 10.1016/0162-0134(88)80025-4 · DOI
  20. Salem, 1982, Kinetic studies on the reduction of cytochrome c, Biochem J, 201, 433, 10.1042/bj2010433 · DOI
  21. Iwahashi, 1989, Enhancement by catechols of hydroxyl-radical formation in the presence of ferric ions and hydrogen peroxide, J Biochem (Tokyo), 105, 429, 10.1093/oxfordjournals.jbchem.a122681 · DOI
  22. Quinlan, 1988, Action of lead (II) and aluminium (III) ions on iron-stimulated lipid peroxidation in liposomes, erythrocytes and rat liver microsomal fractions, Biochim Biophys Acta, 962, 196, 10.1016/0005-2760(88)90159-2 · DOI
  23. Aruoma, 1990, An evaluation of the antioxidant and potential pro-oxidant properties of food additives and trolox c, vitamin E and probucol, Free Radical Res Commun, 10, 143, 10.3109/10715769009149883 · DOI
  24. Wills, 1969, Lipid peroxide formation in microsomes. The role of non-haem iron, Biochem J, 113, 325, 10.1042/bj1130325 · DOI · Paper page
  25. Das, 1986, Effects of flavonoids on induced non-enzymic lipid peroxidation, Prog Clin Biol Med, 213, 243
  26. Davis, 1988, Vitamin E analogue trolox c. ESR and pulse radiolysis studies of free radical reactions, Biochem J, 255, 513
  27. Denis, 1991, Characterization of the activity of purified recombinant human 5-lipoxygenase in the absence and presence of leukocyte factors, J Biol Chem, 266, 5072, 10.1016/S0021-9258(19)67757-4 · DOI
  28. Gutteridge, 1987, Radical-promoting loosely bound iron in biological systems and the bleomycin assay, Life Chem Rep, 4, 113
  29. Porter, 1989, The development of iron chelating drugs, Vol. 2, 257

Cited by

See all 598

Metadata

Authors
Laughton, M. J., Evans, P. J., Moroney, M. A., Hoult, J. R. S., & Halliwell, B.
Venue
Biochemical Pharmacology
Publisher
Elsevier BV
Published
1991-10
Volume
42
Issue
9
Pages
1673-1681
ISSN
0006-2952 (ISSN-L)
DOI
10.1016/0006-2952(91)90501-u
OpenAlex
W1574544450
Cited by
598
References
1
FWCI
8.29
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Inhibition of mammalian 5-lipoxygenase and cyclo-oxygenase by flavonoids and phenolic dietary additives. https://app.cochat.ai/papers/10.1016/0006-2952(91)90501-u
The paper
Laughton, M. J., Evans, P. J., Moroney, M. A., Hoult, J. R. S., & Halliwell, B. (1991). Inhibition of mammalian 5-lipoxygenase and cyclo-oxygenase by flavonoids and phenolic dietary additives. Biochemical Pharmacology. https://doi.org/10.1016/0006-2952(91)90501-u

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.