The biosynthesis of trimethylamine-N-oxide
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Once absorbed by the host, TMA is further metabolized by flavin monooxygenases 1 and 3 (FMO1 and FMO3) in the host liver to generate trimethylamine-N-oxide (TMAO).
“Once TMA is absorbed by the host, it is further metabolized by flavin monooxygenases 1 and 3 (FMO1 and FMO3) in the host liver to generate trimethylamine-N-oxide (TMAO) (8, 15, 16).”
Cites
DETERMINATION OF SERUM PROTEINS BY MEANS OF THE BIURET REACTION
Gornall, A. G., Bardawill, C. J., & David, M. M. (1949) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)57021-6 · Cited by 16,164 · see citing works
ON THE CONVERSION OF SQUALENE TO LANOSTEROL IN VITRO
Tchen, T. T., & Bloch, K. E. (1957) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)70878-8 · Cited by 136 · see citing works
Fish, M. S., Johnson, N. M., Lawrence, E. P., & Horning, E. C. (1955) · Biochimica et Biophysica Acta · doi:10.1016/0006-3002(55)90150-5 · Cited by 74 · see citing works
THE INCORPORATION OF THE CARBOXYL CARBON FROM ACETATE INTO CHOLESTEROL BY RAT LIVER HOMOGENATES
Frantz, I. D., Bucher, N. L. R., Schneider, H. S., et al. (1954) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)71339-2 · Cited by 56 · see citing works
The metabolism of nicotinamide-N-oxide
Chaykin, S., & Bloch, K. E. (1959) · Biochimica et Biophysica Acta · doi:10.1016/0006-3002(59)90458-5 · Cited by 48 · see citing works
Self-citationA NEW COLORIMETRIC METHOD FOR THE ESTIMATION OF POTASSIUM
Jacobs, H. R. D., & Hoffman, W. S. (1931) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)76470-3 · Cited by 43 · see citing works
STUDIES ON TRIMETHYLAMINE OXIDE
Norris, E. R., & Benoit, G. J. (1945) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)43150-x · Cited by 34 · see citing works
The Fate of Trimethylamine Oxide and Trimethylamine in Man
Tarr, H. L. A. (1941) · Journal of the Fisheries Research Board of Canada · doi:10.1139/f40-022 · Cited by 10 · see citing works
Ein Beitrag zum Verhalten des Trimethylamins und des Trimethylaminoxyds im Stoffwechsel
Müller, H. F., & Immendörfer, I. (1942) · Hoppe-Seyler´s Zeitschrift für physiologische Chemie · doi:10.1515/bchm2.1942.275.6.267 · Cited by 9 · see citing works
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Romano, K. A., Vivas, E. I., Amador-Noguez, D., & Rey, F. E. (2015) · mBio · doi:10.1128/mbio.02481-14 · Cited by 777 · see citing works
Poisonings from flesh of the Greenland shark Somniosus microcephalus may be due to trimethylamine
Anthoni, U., Christophersen, C., Gram, L., Nielsen, N. H., & Nielsen, P. (1991) · Toxicon · doi:10.1016/0041-0101(91)90193-u · Cited by 32 · see citing works
- Authors
- Baker, J., & Chaykin, S.
- Affiliations
- University of California, Davis (US)
- ORCID
- Baker, John
- Venue
- Biochimica et Biophysica Acta
- Publisher
- Elsevier BV
- Published
- 1960-07
- Volume
- 41
- Issue
- 3
- Pages
- 548-550
- ISSN
- 0006-3002 (ISSN-L)
- OpenAlex
- W2014216973
- Cited by
- 34
- References
- 9
- Citations by year
- 2022: 1 · 2021: 2 · 2020: 1 · 2018: 1 · 2017: 1 · 2015: 1 · 2014: 1 · 2012: 1
- FWCI
- 1.63
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biochimica et Biophysica Acta (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Polyamine Metabolism and Applications
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Meat and Animal Product Quality
- Physical Sciences › Environmental Science › Environmental Chemistry › Marine Toxins and Detection Methods
- Keywords
- trimethylamine N-oxide, trimethylamine, biosynthesis, Greenland shark, Somniosus microcephalus, ileal smooth muscle contraction, neuromuscular blockade, phrenic nerve-diaphragm preparation
- MeSH terms
- Amines, Methylamines, Oxides
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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